Comparison of quality of life measurements: EQ-5D-5L versus disease/treatment-specific measures in pulmonary embolism and deep vein thrombosis

Abstract Background In the framework of targeted action for continuous safety monitoring, we aimed to evaluate the consistency of indicators derived from available databases for regular reporting. Methods We used a quality of care interpretative model to select characteristics from five national databases, aggregated and linked by homogeneous groups of providers. The target population included all subjects admitted to public hospitals for acute care in four regions of Italy between 2011 and 2013. The association between structures, processes and safety-related outcomes was investigated using odds ratios from generalized estimating equations logistic regression. Outcome measures included claims of malpractice and five patient safety indicators calculated from discharge abstracts using standardized algorithms. Results Over 3 years, claims of malpractice and sepsis increased, whereas deep vein thrombosis and pulmonary embolism decreased. Hospitals with high vs. low volume of discharges were associated with −16% lower rates of claims, but +12% increased risk of sepsis. Compared with research institutes, university clinics had −17% lower rates of claims and −41% cases of dehiscence, with a +32% increased risk of deep vein thrombosis. Local health care authorities recorded −49% deep vein thrombosis, −26% pulmonary embolism, −40% sepsis and +37% risk of claims. Hospitals submitting cases of safe practices and implementing safety recommendations showed significantly higher rates for most outcome measures. Conclusions Indicators from regular databases can be conveniently used to develop a national safety monitoring system for hospital care. Although deeper analysis is needed, institutions with a higher propensity to implement safe practices and recommendations consistently showed higher rates of adverse events.

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More than one in two venous thromboembolism treated in French hospitals occurs during the hospital stays

Phlebology The Journal of Venous Disease ◽

10.1177/0268355515575592 ◽

2015 ◽

Vol 31 (6) ◽

pp. 390-396 ◽

Cited By ~ 2

Author(s):

Francois-André Allaert ◽

Eric Benzenine ◽

Catherine Quantin

Keyword(s):

Pulmonary Embolism ◽

Deep Vein Thrombosis ◽

Venous Thromboembolism ◽

Hospital Stay ◽

Principal Diagnosis ◽

Vein Thrombosis ◽

Icd 10 ◽

Hospital Stays ◽

Deep Vein

Objective The objective was to describe the prevalence of venous thromboembolism, pulmonary embolism, and deep vein thrombosis among hospitalized patients and the percentages of those occurring during the hospital stays. Methods French DRG gave now the opportunity to investigate the frequency of venous thromboembolism occurring during the hospital stay. Statistics are issued from the national PMSI MCO databases encoded using the CIM10. Since 2010–2011 it is possible to differentiate the reason for hospital admission from the pathologies which secondly occurred. Any stay with the ICD-10 codes selected was considered as a hospital-occurred thrombosis unless it was the principal diagnosis of the first medical unit summary. To eliminate outpatient consultations or in day care, stays of <48 h were excluded. Results The results pertain to the 78,838,983 hospitalizations in France from 2005 to 2011 and on the 18,683,603 hospital stays in 2010–2011. The incidence of hospital stays came to 860,343 (1.09%) for venous thromboembolism, with 428,261 (0.543%) for deep vein thrombosis without pulmonary embolism and 432,082 (0.548%) for pulmonary embolism. It corresponds to an incidence of 189 per 100,000 inhabitants. Out of 100 hospital stays involving venous thromboembolism, for 40.3% venous thromboembolism was the cause of hospitalization whereas 59.7% can be considered to have occurred during hospital stay. These distributions are of 25.6 and 74.4% for deep vein thrombosis, respectively, 53.8 and 46.2% for pulmonary embolism. Conclusion The high proportion of hospital-occurred venous thromboembolism is an alarming situation that should question the quality of prevention and/or its effectiveness.

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A Health-Related Quality of Life Measure in Patients with Deep Vein Thrombosis: A Validation Study

Drug Information Journal ◽

10.1177/009286159903300421 ◽

1999 ◽

Vol 33 (4) ◽

pp. 1173-1187 ◽

Cited By ~ 23

Author(s):

Susan D. Mathias ◽

Lee Ann Prebil ◽

Caryn G. Putterman ◽

Joseph J. Chmiel ◽

Richard C. Throm ◽

...

Keyword(s):

Quality Of Life ◽

Deep Vein Thrombosis ◽

Validation Study ◽

Health Related Quality ◽

Life Measure ◽

Vein Thrombosis ◽

Related Quality ◽

Health Related ◽

Deep Vein

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Comparison of Pharmacomechanical Catheter-Directed Thrombolysis versus Catheter-Directed Thrombolysis for the treatment of acute iliofemoral deep vein thrombosis: Measures of long term clinical outcome and quality of life

Annals of Vascular Surgery ◽

10.1016/j.avsg.2021.03.040 ◽

2021 ◽

Author(s):

Tianan Huang ◽

Wenbin Ding ◽

Zhuo Chen ◽

Yu Yin ◽

Jingfan Yu ◽

...

Keyword(s):

Quality Of Life ◽

Deep Vein Thrombosis ◽

Clinical Outcome ◽

Vein Thrombosis ◽

Catheter Directed Thrombolysis ◽

Deep Vein

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Health-related quality of life after deep vein thrombosis

SpringerPlus ◽

10.1186/s40064-016-2949-z ◽

2016 ◽

Vol 5 (1) ◽

Cited By ~ 15

Author(s):

Kristin Kornelia Utne ◽

Mazdak Tavoly ◽

Hilde Skuterud Wik ◽

Lars Petter Jelsness-Jørgensen ◽

René Holst ◽

...

Keyword(s):

Quality Of Life ◽

Deep Vein Thrombosis ◽

Health Related Quality ◽

Vein Thrombosis ◽

Related Quality ◽

Health Related ◽

Deep Vein

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Deep vein thrombosis and our treatment applications: 12-year results

Journal of Clinical Images and Medical Case Reports ◽

10.52768/2766-7820/1253 ◽

2021 ◽

Vol 2 (4) ◽

Author(s):

Borulu F ◽

◽

Erkut B ◽

Keyword(s):

Quality Of Life ◽

Molecular Weight ◽

Deep Vein Thrombosis ◽

Low Molecular Weight Heparin ◽

Mechanical Thrombectomy ◽

Heparin Therapy ◽

Low Molecular Weight ◽

Vein Thrombosis ◽

Deep Vein

Introduction: Deep vein thrombosis is an important health problem that is frequently encountered in the general population and especially in surgical clinics and has a negative impact on quality of life. In this study, treatment options and results of patients with deep vein thrombosis who have been hospitalized for 12 years in Atatürk University and Erzurum Regional Hospital were examined and discussed. Methods: In our clinic, 412 cases of deep vein thrombosis (211 female, 201 male) were hospitalized between 2009 and 2021. The mean age of the patients was 49 ± 19 years. While medical treatment with heparin was given to all 412 patients; thrombolytic therapy, surgical embolectomy (vascular and pulmoner), and pharmaco-mechanical thrombectomy were applied to some of these patients. Results: Deep vein thrombosis was more common in the lower extremity (n=322, 78.2%). All patients had at least one of the complaints of pain, swelling and redness. All cases were diagnosed by color Doppler ultrasonography. Medically, standard and low molecular weight heparin therapy was given to all patients after hospitalization. Thrombolytic therapy was applied to 66 (16,1%) of the cases, pulmonary embolectomy to 8 (1,9%), surgical thrombectomy to 10 (2,4%) and pharmacomechanical thrombectomy to 44 (10,7%) patients. In addition to these 120 patients (29.1%), a vena cava filter was placed for prophylactic purposes. Conclusions: In patients diagnosed with deep vein thrombosis and hospitalized, the diagnosis should be supported by Doppler ultrasound in addition to clinical diagnosis after an etiology investigation. Early diagnosis, rapid and effective treatment methods are important for the subsequent quality of life of patients. In addition to low molecular weight heparins being the first choice agents, standard heparin administration still needs to be applied in some clinical pictures. In addition, we believe that pharmacomechanical thrombectomy can be applied in appropriate acute cases. Keywords: Deep vein thrombosis; anticoagulant treatment; heparin therapy; low-molecular-weight heparin; mechanical thrombectomy.

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Treatment of Acute Iliofemoral Deep Vein Thrombosis; Does Catheter Directed Thrombolytic Therapy Change Outcomes?

Cardiology Open Access ◽

10.33140/coa.04.03.01 ◽

2019 ◽

Vol 4 (3) ◽

Keyword(s):

Quality Of Life ◽

Deep Vein Thrombosis ◽

Iliac Vein ◽

P Value ◽

Vein Thrombosis ◽

Catheter Directed Thrombolysis ◽

Group A ◽

Deep Vein

Background: Iliofemoral deep vein thrombosis (DVT) is associated with severe post-thrombotic morbidity when treated with anticoagulation alone. Catheter- directed thrombolysis (CDT) allows early removal of thrombus and reduces valvular reflux and Post-thrombotic Syndrome (PTS). Patients and methods: This prospective randomized multi-center controlled two- arm blind study was conducted in 6 centers on 252 patients with iliofemoral DVT. Patients were randomly allocated by using simple random allocation cards method into two groups; Group (A): CDT followed by oral anticoagulation (N=126 (50%)), Group (B): Standard DVT therapy (N=126 (50%)). Follow-up was for 24 months. Results: Patients of group (A) significantly complained less pain at 10 & 30 days (P-Value: 0.02 & 0.04 respectively). Also there was significant decrease in leg circumference in group (A) at 10 & 30 days (P-Value: 0.001 & 0.03 respectively). Patency of iliac vein segment was significantly higher in group (A) during the 24 months follow up (P-Value <0.001 (HS)). Patients in group (A) developed less PTS at six months, at one year and at two years (P-Value: 0.024, 0.017 and 0.035 respectively). Better Quality of life was observed in group (A) (P-Value: 0.003). Conclusion: Addition of catheter-directed thrombolysis in the treatment of acute iliofemoral DVT; was safe and tolerated by most of the patients with better effect to reduce leg pain & circumference. It was considered a protecting weapon to prevent post-thrombotic syndrome and so improve quality of life and was related to achievement of higher iliac vein patency and less reflux.

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