The design of the environmentally friendly approach to the synthesis of biologically important
compounds without compromising the yield has been the focus of many chemists in recent
years. The development of the one-pot synthesis of heterocycles in the presence of Ionic Liquids
(ILs), used as both environmental media and catalysts, is efficient and environmentally sustainable.
This review highlights the one-pot synthesis of imidazoles in acidic ILs in the past decade. Some reviews
have been conducted on imidazoles, such as their pharmacological importance. Hence, we decided
to focus on their synthesis in acidic ionic liquids, which the authors are not aware of any published
literature.