Rectification concerning “Isolation and characterization of a novel anthocyanin-promoting MYBA gene family in Citrus”

Abstract R and B genes and their homologues encode basic helix-loop-helix (bHLH) transcriptional activators that regulate the anthocyanin biosynthetic pathway in flowering plants. In maize, R/B genes comprise a very small gene family whose organization reflects the unique evolutionary history and genome architecture of maize. To know whether the organization of the R gene family could provide information about the origins of the distantly related grass rice, we characterized members of the R gene family from rice Oryza sativa. Despite being a true diploid, O. sativa has at least two R genes. An active homologue (Ra) with extensive homology with other R genes is located at a position on chromosome 4 previously shown to be in synteny with regions of maize chromosomes 2 and 10 that contain the B and R loci, respectively. A second rice R gene (Rb) of undetermined function was identified on chromosome 1 and found to be present only in rice species with AA genomes. All non-AA species have but one R gene that is Ra-like. These data suggest that the common ancestor shared by maize and rice had a single R gene and that the small R gene families of grasses have arisen recently and independently.

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Isolation and Characterization of Rat Cytochrome P-450IIB Gene Family Members

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)83538-4 ◽

1989 ◽

Vol 264 (12) ◽

pp. 7046-7053 ◽

Cited By ~ 3

Author(s):

C M Giachelli ◽

J Lin-Jones ◽

C J Omiecinski

Keyword(s):

Gene Family ◽

Family Members ◽

Isolation And Characterization

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Isolation and characterization of theXenopusHIVEP gene family

European Journal of Biochemistry ◽

10.1111/j.1432-1033.2004.04017.x ◽

2004 ◽

Vol 271 (6) ◽

pp. 1135-1144 ◽

Cited By ~ 5

Author(s):

Ulrike Dürr ◽

Kristine A. Henningfeld ◽

Thomas Hollemann ◽

Walter Knöchel ◽

Tomas Pieler

Keyword(s):

Gene Family ◽

Isolation And Characterization

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Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart

Molecular and Cellular Biology ◽

10.1128/mcb.11.1.126-133.1991 ◽

1991 ◽

Vol 11 (1) ◽

pp. 126-133 ◽

Cited By ~ 1

Author(s):

N Bacher ◽

Y Zisman ◽

E Berent ◽

E Livneh

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Gene Family ◽

Phorbol Esters ◽

Structural Features ◽

Cos Cells ◽

Isolation And Characterization ◽

Kinase C ◽

Human Epidermoid Carcinoma

We have isolated and characterized a new human cDNA, coding for a protein kinase, related to the protein kinase C (PKC) gene family. Although this protein kinase shares some homologous sequences and structural features with the four members of the PKC family initially isolated (alpha, beta I, beta II, and gamma), it shows more homology with the recently described PKC-related subfamily, encoded by the cDNAs delta, epsilon, and zeta. The transcript for this gene product, termed PKC-L, is most abundant in lung tissue, less expressed in heart and skin tissue, and exhibited very low expression in brain tissue. Thus, its tissue distribution is different from that described for other mammalian members of the PKC gene family, their expression being enriched in brain tissues. PKC-L is also expressed in several human cell lines, including the human epidermoid carcinoma line A431. The ability of phorbol esters to bind to and stimulate the kinase activity of PKC-L was revealed by introducing the cDNA into COS cells.

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