Comprehensive two-dimensional gas chromatography–time-of-flight mass spectrometry (GC × GC-TOF) for high resolution metabolomics: biomarker discovery on spleen tissue extracts of obese NZO compared to lean C57BL/6 mice

Werner Welthagen; Robert A. Shellie; Joachim Spranger; Michael Ristow; Ralf Zimmermann; Oliver Fiehn

doi:10.1007/s11306-005-1108-2

Comprehensive two-dimensional gas chromatography–time-of-flight mass spectrometry (GC × GC-TOF) for high resolution metabolomics: biomarker discovery on spleen tissue extracts of obese NZO compared to lean C57BL/6 mice

Metabolomics ◽

10.1007/s11306-005-1108-2 ◽

2005 ◽

Vol 1 (1) ◽

pp. 65-73 ◽

Cited By ~ 125

Author(s):

Werner Welthagen ◽

Robert A. Shellie ◽

Joachim Spranger ◽

Michael Ristow ◽

Ralf Zimmermann ◽

...

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

High Resolution ◽

Biomarker Discovery ◽

Time Of Flight ◽

Two Dimensional ◽

Spleen Tissue ◽

Flight Mass Spectrometry ◽

Tissue Extracts ◽

High Resolution Metabolomics

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Coupling needle-trap devices with comprehensive two-dimensional gas chromatography with high-resolution time-of-flight mass spectrometry to rapidly reveal the chemical transformation of volatile components from sulfur-fumigatedginseng

Journal of Separation Science ◽

10.1002/jssc.201401362 ◽

2015 ◽

Vol 38 (7) ◽

pp. 1248-1253 ◽

Cited By ~ 7

Author(s):

Gang Cao ◽

Qinglin Li ◽

Xin Wu ◽

Jida Zhang ◽

Hongyan Zhang ◽

...

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

High Resolution ◽

Chemical Transformation ◽

Time Of Flight ◽

Volatile Components ◽

Two Dimensional ◽

Resolution Time ◽

Flight Mass Spectrometry

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Application of inert gas-mediated ionization for qualitative screening of chlorinated aromatics in house dust by comprehensive two-dimensional gas chromatography–high-resolution time-of-flight mass spectrometry

Journal of Chromatography A ◽

10.1016/j.chroma.2021.462571 ◽

2021 ◽

pp. 462571

Author(s):

Teruyo Ieda ◽

Shunji Hashimoto ◽

Kiyoshi Tanabe ◽

Akitoshi Goto ◽

Tatsuya Kunisue

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

High Resolution ◽

House Dust ◽

Time Of Flight ◽

Inert Gas ◽

Two Dimensional ◽

Resolution Time ◽

Chlorinated Aromatics ◽

Flight Mass Spectrometry

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Deeper investigation of oxygen-containing compounds in oleaginous feedstock (animal fat) by preparative column chromatography and comprehensive two-dimensional gas chromatography coupled with high-resolution time-of-flight mass spectrometry

Talanta ◽

10.1016/j.talanta.2021.123019 ◽

2021 ◽

pp. 123019

Author(s):

Marco Beccaria ◽

Yun Zou ◽

Pierre-Hugues Stefanuto ◽

Anna Luiza Mendes Siqueira ◽

Adrien Maniquet ◽

...

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

High Resolution ◽

Column Chromatography ◽

Time Of Flight ◽

Two Dimensional ◽

Resolution Time ◽

Animal Fat ◽

Flight Mass Spectrometry

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Comprehensive two-dimensional gas chromatography coupled to high resolution time-of-flight mass spectrometry for screening of organohalogenated compounds in cat hair

Journal of Chromatography A ◽

10.1016/j.chroma.2017.08.055 ◽

2018 ◽

Vol 1536 ◽

pp. 151-162 ◽

Cited By ~ 7

Author(s):

Martin Brits ◽

Peter Gorst-Allman ◽

Egmont R. Rohwer ◽

Jayne De Vos ◽

Jacob de Boer ◽

...

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

High Resolution ◽

Time Of Flight ◽

Two Dimensional ◽

Resolution Time ◽

Flight Mass Spectrometry

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Analysis of human plasma lipids by using comprehensive two-dimensional gas chromatography with dual detection and with the support of high-resolution time-of-flight mass spectrometry for structural elucidation

Journal of Separation Science ◽

10.1002/jssc.201400844 ◽

2014 ◽

Vol 38 (2) ◽

pp. 267-275 ◽

Cited By ~ 12

Author(s):

Simona Salivo ◽

Marco Beccaria ◽

Giuseppe Sullini ◽

Peter Q. Tranchida ◽

Paola Dugo ◽

...

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

High Resolution ◽

Human Plasma ◽

Plasma Lipids ◽

Time Of Flight ◽

Two Dimensional ◽

Resolution Time ◽

Flight Mass Spectrometry ◽

Dual Detection

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Pixel-by-pixel correction of retention time shifts in chromatograms from comprehensive two-dimensional gas chromatography coupled to high resolution time-of-flight mass spectrometry

Journal of Chromatography A ◽

10.1016/j.chroma.2017.05.065 ◽

2017 ◽

Vol 1508 ◽

pp. 121-129 ◽

Cited By ~ 12

Author(s):

Yasuyuki Zushi ◽

Jonas Gros ◽

Qingping Tao ◽

Stephen E. Reichenbach ◽

Shunji Hashimoto ◽

...

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

High Resolution ◽

Retention Time ◽

Time Of Flight ◽

Two Dimensional ◽

Resolution Time ◽

Flight Mass Spectrometry

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Breathomics to diagnose systemic sclerosis using thermal desorption and comprehensive two-dimensional gas chromatography high-resolution time-of-flight mass spectrometry

Analytical and Bioanalytical Chemistry ◽

10.1007/s00216-021-03333-4 ◽

2021 ◽

Author(s):

Delphine Zanella ◽

Julien Guiot ◽

Pierre-Hugues Stefanuto ◽

Laurie Giltay ◽

Monique Henket ◽

...

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

Systemic Sclerosis ◽

High Resolution ◽

Thermal Desorption ◽

Time Of Flight ◽

Two Dimensional ◽

Resolution Time ◽

Flight Mass Spectrometry

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Comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry for metabonomics: Biomarker discovery for diabetes mellitus

Analytica Chimica Acta ◽

10.1016/j.aca.2008.11.058 ◽

2009 ◽

Vol 633 (2) ◽

pp. 257-262 ◽

Cited By ~ 169

Author(s):

Xiang Li ◽

Zhiliang Xu ◽

Xin Lu ◽

Xuehui Yang ◽

Peiyuan Yin ◽

...

Keyword(s):

Diabetes Mellitus ◽

Mass Spectrometry ◽

Gas Chromatography ◽

Biomarker Discovery ◽

Time Of Flight ◽

Two Dimensional ◽

Flight Mass Spectrometry

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Comprehensive two-dimensional gas chromatography coupled to high-resolution time-of-flight mass spectrometry and simultaneous nitrogen phosphorous and mass spectrometric detection for characterization of nanoparticles in roadside atmosphere

Journal of Chromatography A ◽

10.1016/j.chroma.2007.02.001 ◽

2007 ◽

Vol 1150 (1-2) ◽

pp. 13-20 ◽

Cited By ~ 67

Author(s):

Nobuo Ochiai ◽

Teruyo Ieda ◽

Kikuo Sasamoto ◽

Akihiro Fushimi ◽

Shuichi Hasegawa ◽

...

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

High Resolution ◽

Time Of Flight ◽

Mass Spectrometric ◽

Mass Spectrometric Detection ◽

Two Dimensional ◽

Resolution Time ◽

Flight Mass Spectrometry

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Analysis of fresh Mentha haplocalyx volatile components by comprehensive two-dimensional gas chromatography and high-resolution time-of-flight mass spectrometry

The Analyst ◽

10.1039/c1an15616k ◽

2011 ◽

Vol 136 (22) ◽

pp. 4653 ◽

Cited By ~ 21

Author(s):

Gang Cao ◽

Qiyuan Shan ◽

Xiaomeng Li ◽

Xiaodong Cong ◽

Yun Zhang ◽

...

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

High Resolution ◽

Time Of Flight ◽

Volatile Components ◽

Two Dimensional ◽

Resolution Time ◽

Flight Mass Spectrometry

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