Long-lasting impairments in rodent oxygen-induced retinopathy measured by retinal vessel density and visual function

2018 ◽  
Vol 62 (5) ◽  
pp. 681-690 ◽  
Author(s):  
Xu Wang ◽  
Ke Shen ◽  
Fang Lu ◽  
Shigang He
Keyword(s):  
Visual Function ◽  
Retinal Vessel ◽  
Vessel Density ◽  
Oxygen Induced Retinopathy ◽  
Retinal Vessel Density

scholarly journals Reduced retinal vessel density in COVID-19 patients and elevated D-dimer levels during the acute phase of the infection

2021 ◽  
Author(s):  
Noemi Guemes-Villahoz ◽  
Barbara Burgos-Blasco ◽  
Beatriz Vidal-Villegas ◽  
Juan Donate-López ◽  
Francisco Javier Martín-Sánchez ◽  
...  
Keyword(s):  
Acute Phase ◽  
Retinal Vessel ◽  
Vessel Density ◽  
Retinal Vessel Density ◽  
D Dimer

Albuminuria and retinal vessel density in diabetes without diabetic retinopathy: the Kailuan Eye Study

2020 ◽  
Author(s):  
Qian Wang ◽  
Lili Liu ◽  
Jost B. Jonas ◽  
Bixia Gao ◽  
Shou Ling Wu ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Retinal Vessel ◽  
Vessel Density ◽  
Retinal Vessel Density

scholarly journals Reduced retinal vessel density in COVID-19 patients and elevated D-dimer levels during the acute phase of the infection

2021 ◽  
Vol 156 (11) ◽  
pp. 541-546
Author(s):  
Noemi Guemes-Villahoz ◽  
Barbara Burgos-Blasco ◽  
Beatriz Vidal-Villegas ◽  
Juan Donate-López ◽  
Francisco Javier Martín-Sánchez ◽  
...  
Keyword(s):  
Acute Phase ◽  
Retinal Vessel ◽  
Vessel Density ◽  
Retinal Vessel Density ◽  
D Dimer

scholarly journals Retinal and Choriocapillary Vascular Changes in Early Stages of Multiple Sclerosis: A Prospective Study

2021 ◽  
Vol 10 (24) ◽  
pp. 5756
Author(s):  
Daniela Montorio ◽  
Roberta Lanzillo ◽  
Antonio Carotenuto ◽  
Maria Petracca ◽  
Marcello Moccia ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Retinal Vessel ◽  
Vessel Density ◽  
Ganglion Cell Complex ◽  
Healthy Controls ◽  
Fiber Layer ◽  
Density Reduction ◽  
Capillary Plexus ◽  
Retinal Vessel Density ◽  
A Prospective Study

Optical Coherence Tomography Angiography (OCTA) abnormalities occur in multiple sclerosis (MS) over the course of the disease. OCTA investigations at early MS stages are lacking. We aimed to investigate vessel density in macular and papillary regions over two years after an initial demyelinating event (IDE). Vessel density was analyzed in superficial, deep, choriocapillaris and radial peripapillary plexus at baseline, and after one and two years. We also evaluated structural OCT parameter changes of the ganglion cell complex (GCC) and retinal nerve fiber layer (RNFL). We evaluated 30 eyes from 15 IDE patients (7 females, 8 males, mean age 28.4 ± 9.6 years) and 30 eyes from 15 healthy controls. After 2 years, we reported in the IDE group a reduced vessel density in the superficial capillary plexus, deep capillary plexus and radial peripapillary capillary plexus with respect to the baseline (coeff. β = −2.779, p = 0.013; coeff. β = −4.055, p = 0.018 and coeff. β = −2.687, p ≤ 0.001; respectively), while GCC and RNFL thicknesses did not change. Vessel density reduction was not associated with an expanded disability status scale (EDSS) change, relapse occurrence or magnetic resonance imaging activity. The analysis of healthy controls did not reveal any impairment in OCT and OCTA parameters over 2 years of follow-up. Retinal vascular loss occurs in patients with an IDE independently from clinical and radiological disease activity. Retinal vessel density could represent a novel early biomarker to monitor the MS pathological burden.

Parafoveal Retinal Vessel Density Assessment by Optical Coherence Tomography Angiography in Healthy Eyes

2018 ◽  
Vol 49 (10) ◽  
pp. S5-S17 ◽  
Author(s):  
Malvika Arya ◽  
Carl B. Rebhun ◽  
A. Yasin Alibhai ◽  
Xuejing Chen ◽  
Carlos Moreira-Neto ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Retinal Vessel ◽  
Vessel Density ◽  
Optical Coherence ◽  
Retinal Vessel Density ◽  
Healthy Eyes ◽  
Density Assessment

Comparison of Pre-Treatment vs. Post-Treatment Retinal Vessel Density in Children with Amblyopia

2020 ◽  
Vol 70 (3) ◽  
pp. 79-85
Author(s):  
Robert C. Gunzenhauser ◽  
Irena Tsui ◽  
Federico G. Velez ◽  
Simon SM Fung ◽  
Joseph L. Demer ◽  
...  
Keyword(s):  
Retinal Vessel ◽  
Post Treatment ◽  
Vessel Density ◽  
Pre Treatment ◽  
Retinal Vessel Density

scholarly journals The Difference in Repeatability of Automated Superficial Retinal Vessel Density according to the Measurement Area Using OCT Angiography

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Hyung Bin Lim ◽  
Tae Seen Kang ◽  
Yeo Kyoung Won ◽  
Jung Yeul Kim
Keyword(s):  
Intraclass Correlation ◽  
Retinal Vessel ◽  
Vessel Density ◽  
Foveal Avascular Zone ◽  
Capillary Plexus ◽  
The Difference ◽  
Retinal Vessel Density ◽  
Perfusion Density ◽  
Measurement Area ◽  
Central Fovea

Purpose. To evaluate the difference in the repeatability of automated superficial retinal vessel density and foveal avascular zone (FAZ) metrics according to the measurement area of optical coherence tomography angiography (OCTA). Methods. A total of 127 normal eyes from 127 healthy subjects were included. Macular angiography images were acquired from all subjects using the Zeiss Cirrus 5000 with AngioPlex™ OCTA software. Scans of 3 × 3 mm and 6 × 6 mm were each performed twice in a randomly arranged sequence. Vessel density (VD), perfusion density (PD), and FAZ metrics of the superficial capillary plexus were calculated automatically for all scans, and the repeatabilities for both scan patterns were assessed based on intraclass correlation (ICC), coefficient of variation (CV), and coefficient of repeatability (CR) parameters. The average measured values in the two scan patterns were also compared. Results. VD was significantly greater in the 3 × 3 mm scan than in the 6 × 6 mm scan according to all parameters, whereas PD was significantly less in the 3 × 3 mm scan than in the 6 × 6 mm scan. The ICCs for VDs in the central fovea were 0.826 and 0.741 for the 3 × 3 and 6 × 6 mm scans, respectively, and the CVs were 8.00% and 12.75%. For PDs, the ICCs were 0.839 and 0.762 and the CVs were 9.32% and 14.90%. The FAZ metrics in the 3 × 3 mm scan showed good repeatability with an ICC >0.75 and a CV <10.0%. However, all ICCs for the 6 × 6 mm scans were <0.75, and the CVs were all >10%. Conclusions. The 6 × 6 mm macular angiography scans resulted in lower repeatabilities than the 3 × 3 mm scans according to all OCTA parameters, particularly in the central fovea and FAZ metrics. The 3 × 3 mm scan was more suitable than the 6 × 6 mm scan for analyzing macular microvascular density and FAZ metrics.

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