Relation between cancer cellularity and apparent diffusion coefficient values using diffusion-weighted magnetic resonance imaging in breast cancer

2008 ◽  
Vol 26 (4) ◽  
pp. 222-226 ◽  
Author(s):  
Miho I. Yoshikawa ◽  
Shozo Ohsumi ◽  
Shigenori Sugata ◽  
Masaaki Kataoka ◽  
Shigemitsu Takashima ◽  
...  
2013 ◽  
Vol 6 ◽  
pp. MRI.S11149 ◽  
Author(s):  
Melanie Martin

This article reviews a new concept in magnetic resonance as applied to cellular and biological systems. Diffusion weighted magnetic resonance imaging can be used to infer information about restriction sizes of samples being measured. The measurements rely on the apparent diffusion coefficient changing with diffusion times as measurements move from restricted to free diffusion regimes. Pulsed gradient spin echo (PGSE) measurements are limited in the ability to shorten diffusion times and thus are limited in restriction sizes which can be probed. Oscillating gradient spin echo (OGSE) measurements could provide shorter diffusion times so smaller restriction sizes could be probed.


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