scholarly journals A Comment on ‘Changes in Bone Mineral Density in Women Following 1-year Gastric Bypass Surgery’ Published by Casagrande DS et al.

2013 ◽  
Vol 23 (11) ◽  
pp. 1885-1885
Author(s):  
Wojciech Pluskiewicz ◽  
Marek Buzga ◽  
Pavol Holeczy ◽  
Vit Šmajstrla ◽  
Piotr Adamczyk
Keyword(s):  
Bone Mineral Density ◽  
Gastric Bypass ◽  
Bone Mineral ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Mineral Density

P-26: Changes in bone mineral density and body composition following Roux-en-Y gastric bypass surgery

2009 ◽  
Vol 5 (3) ◽  
pp. S33
Author(s):  
Jamie Seiler ◽  
G. Craig Wood ◽  
Eric Newman ◽  
Jennifer Fernandez ◽  
Glenn Gerhard ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Gastric Bypass ◽  
Body Composition ◽  
Bone Mineral ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Mineral Density

Changes in Bone Mineral Density in Women Following 1-Year Gastric Bypass Surgery

2012 ◽  
Vol 22 (8) ◽  
pp. 1287-1292 ◽  
Author(s):  
Daniela Schaan Casagrande ◽  
Giuseppe Repetto ◽  
Claudio Corá Mottin ◽  
Jatin Shah ◽  
Ricardo Pietrobon ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Gastric Bypass ◽  
Bone Mineral ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Mineral Density

scholarly journals Erratum to: Changes in Bone Mineral Density in Women Following 1-Year Gastric Bypass Surgery

2015 ◽  
Vol 25 (9) ◽  
pp. 1763-1763
Author(s):  
Daniela Schaan Casagrande ◽  
Giuseppe Repetto ◽  
Claudio Corá Mottin ◽  
Jatin Shah ◽  
Ricardo Pietrobon ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Gastric Bypass ◽  
Bone Mineral ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Mineral Density

scholarly journals Bone Mineral Density, Parathyroid Hormone, and Vitamin D After Gastric Bypass Surgery: a 10-Year Longitudinal Follow-Up

2020 ◽  
Vol 30 (12) ◽  
pp. 4995-5000
Author(s):  
Mustafa Raoof ◽  
Ingmar Näslund ◽  
Eva Rask ◽  
Eva Szabo
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Gastric Bypass ◽  
Parathyroid Hormone ◽  
Femoral Neck ◽  
Bone Mineral ◽  
Gastric Bypass Surgery ◽  
Serum Levels ◽  
Massive Weight Loss ◽  
Mineral Density

Abstract Background The aim of the present study was to study longitudinal changes in bone mineral density (BMD), vitamin D, and parathyroid hormone (PTH) levels in females over a 10-year period after laparoscopic Roux-en-Y gastric bypass (LRYGB). Methods Twenty-three women, mean age 43.4 ± 8.7 years and mean body mass index (BMI) 44.6 ± 5.17 kg/m2 at baseline, were included. BMD, BMI, S-calcium, S-25(OH)-vitamin D, and fP-PTH were measured preoperatively and 2, 5, and 10 years postoperatively. Results Ten years after surgery, BMD of the spine and femoral neck decreased by 20% and 25%, respectively. Changes in serum levels of vitamin D, PTH, and calcium over the same period were small. Conclusion After LRYGB with subsequent massive weight loss, a large decrease in BMD of the spine and femoral neck was seen over a 10-year postoperative period. The fall in BMD largely occurred over the first 5 years after surgery.

scholarly journals Continuous decline in bone mineral density and deterioration of bone microarchitecture 7 years after Roux-en-Y gastric bypass surgery

2020 ◽  
Vol 182 (3) ◽  
pp. 303-311 ◽  
Author(s):  
Stinus Hansen ◽  
Niklas Rye Jørgensen ◽  
Anne Pernille Hermann ◽  
Rene Klinkby Støving
Keyword(s):  
Bone Mineral Density ◽  
Gastric Bypass ◽  
Bone Strength ◽  
Bone Mineral ◽  
Bone Microarchitecture ◽  
Gastric Bypass Surgery ◽  
Bone Geometry ◽  
Mineral Density ◽  
Quantitative Ct ◽  
Post Surgery

Objective Roux-en-Y-gastric bypass (RYGB) surgery is an effective treatment for morbid obesity. A possible overlooked side effect is negative bone metabolic consequences. Design A seven-year prospective study following ten women and seven men after RYGB (baseline mean age 43 ± 8 years, BMI 42 ± 6 kg/m2). Methods Lumbar spine and total hip bone mineral density (BMD) using dual energy x-ray absorptiometry, distal radius and tibia bone geometry, volumetric BMD, microarchitecture and finite element estimated bone strength using high-resolution peripheral quantitative CT and biochemical markers of bone remodelling were assessed at baseline, 2 and 7 years. Results Compared to baseline, body weight was 24 ± 10% lower after 2 years and 21 ± 11% after 7 years. During the 7 years of follow-up, radius and tibia vBMD had declined 13 ± 8% and 8 ± 7% from baseline to 2 years and further 10 ± 7% and 7 ± 8% from 2 to 7 years (all P < 0.001). At both radius and tibia, cortical thickness declined and cortical porosity increased. From baseline to 7 years, there were clear indications of deteriorations of the trabecular network with fewer, more widely spaced and more in-homogeneously distributed trabeculae in both radius and tibia. Overall, declines in estimated bone strength of 16 ± 9% in radius and 16 ± 7% in tibia were observed (both P < 0.001). Conclusion Seven years after RYGB, evidence of continuous declines in BMD and ongoing deterioration of bone microarchitecture and reduced estimated bone strength compared to baseline and 2 years post-surgery results were found. These findings emphasize the need for regular assessment of bone health in patients with prior RYGB.

scholarly journals Bone Mineral Density and Turnover After Sleeve Gastrectomy and Gastric Bypass: A Randomized Controlled Trial (Oseberg)

2020 ◽  
Author(s):  
Dag Hofsø ◽  
Thor Olav Widerøe Hillestad ◽  
Erling Halvorsen ◽  
Farhat Fatima ◽  
Line Kristin Johnson ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Gastric Bypass ◽  
Sleeve Gastrectomy ◽  
Lumbar Spine ◽  
Femoral Neck ◽  
Bone Turnover ◽  
Bone Mineral ◽  
Bone Turnover Markers ◽  
Mineral Density ◽  
Turnover Markers

Abstract Context Bariatric surgery, particularly Roux-en-Y gastric bypass (RYGB), is associated with an increased risk of osteoporotic fractures. It is unknown whether RYGB or sleeve gastrectomy (SG) have different effects on bone health. Objective To compare changes in bone mineral density and markers of bone turnover 1 year after SG and RYGB. Design, Setting, Patients, and Interventions Randomized, triple-blind, single-center trial at a tertiary care center in Norway. The primary outcome was diabetes remission. Patients with severe obesity and type 2 diabetes were randomized and allocated (1:1) to SG or RYGB. Main Outcome Measures Changes in areal bone mineral density (aBMD) and bone turnover markers. Results Femoral neck, total hip, and lumbar spine aBMD, but not total body aBMD, decreased significantly more after RYGB (n = 44) than after SG (n = 48) (mean [95% confidence interval] between group differences -2.8% [-4.7 to -0.8], -3.0% [-5.0 to -0.9], -4.2% [-6.4 to -2.1], and -0.5% [-1.6 to 0.6], respectively). The increase in procollagen type 1 N-terminal propeptide (P1NP) and C-telopeptide of type I collagen (CTX-1) were approximately 100% higher after RYGB than after SG (between group difference at 1 year, both P &lt; 0.001). The changes in femoral neck, total hip, and lumbar spine aBMDs and the changes in P1NP and CTX-1 were independently associated with the surgical procedure (all P &lt; 0.05) and not weight change. Conclusions Roux-en-Y gastric bypass was associated with a greater reduction in aBMD and a greater increase in bone turnover markers compared with SG. This finding could suggest greater skeletal fragility after RYGB.

scholarly journals Bone metabolism, bone mineral density and low-energy fractures 10 years after Roux-en-Y gastric bypass

Bone ◽  
2019 ◽  
Vol 127 ◽  
pp. 436-445 ◽  
Author(s):  
Ingvild Kristine Blom-Høgestøl ◽  
Stephen Hewitt ◽  
Monica Chahal-Kummen ◽  
Cathrine Brunborg ◽  
Hanne Løvdal Gulseth ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Gastric Bypass ◽  
Bone Metabolism ◽  
Bone Mineral ◽  
Low Energy ◽  
Mineral Density

Roux-en-Y gastric bypass reduces bone mineral density independent of body weight in rats

Appetite ◽  
2010 ◽  
Vol 54 (3) ◽  
pp. 660 ◽  
Author(s):  
T.A. Lutz ◽  
M. Bueter ◽  
J.J. Hillebrand ◽  
A. Liesegang ◽  
C.W. Leroux
Keyword(s):  
Bone Mineral Density ◽  
Gastric Bypass ◽  
Body Weight ◽  
Bone Mineral ◽  
Mineral Density
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