Propensity Score–Matching Sleeve Gastrectomy (SG) vs. Gastric Bypass (RYGB) in Patients ≥ 60 Years

2021 ◽  
Author(s):  
Omar Thaher ◽  
Stefanie Wolf ◽  
Martin Hukauf ◽  
Christine Stroh
Keyword(s):  
Gastric Bypass ◽  
Sleeve Gastrectomy ◽  
Propensity Score ◽  
Propensity Score Matching

scholarly journals 30-day morbidity and mortality of sleeve gastrectomy, Roux-en-Y gastric bypass and one anastomosis gastric bypass: a propensity score-matched analysis of the GENEVA data

2021 ◽  
Author(s):  
Rishi Singhal ◽  
Victor Roth Cardoso ◽  
Tom Wiggins ◽  
Jonathan Super ◽  
Christian Ludwig ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Sleeve Gastrectomy ◽  
Propensity Score ◽  
Complication Rate ◽  
Morbidity And Mortality ◽  
One Anastomosis Gastric Bypass ◽  
Complication Rates ◽  
Significant Difference ◽  
Observational Cohort ◽  
Insulin Dependent

Abstract Background There is a paucity of data comparing 30-day morbidity and mortality of sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB), and one anastomosis gastric bypass (OAGB). This study aimed to compare the 30-day safety of SG, RYGB, and OAGB in propensity score-matched cohorts. Materials and methods This analysis utilised data collected from the GENEVA study which was a multicentre observational cohort study of bariatric and metabolic surgery (BMS) in 185 centres across 42 countries between 01/05/2022 and 31/10/2020 during the Coronavirus Disease-2019 (COVID-19) pandemic. 30-day complications were categorised according to the Clavien–Dindo classification. Patients receiving SG, RYGB, or OAGB were propensity-matched according to baseline characteristics and 30-day complications were compared between groups. Results In total, 6770 patients (SG 3983; OAGB 702; RYGB 2085) were included in this analysis. Prior to matching, RYGB was associated with highest 30-day complication rate (SG 5.8%; OAGB 7.5%; RYGB 8.0% (p = 0.006)). On multivariate regression modelling, Insulin-dependent type 2 diabetes mellitus and hypercholesterolaemia were associated with increased 30-day complications. Being a non-smoker was associated with reduced complication rates. When compared to SG as a reference category, RYGB, but not OAGB, was associated with an increased rate of 30-day complications. A total of 702 pairs of SG and OAGB were propensity score-matched. The complication rate in the SG group was 7.3% (n = 51) as compared to 7.5% (n = 53) in the OAGB group (p = 0.68). Similarly, 2085 pairs of SG and RYGB were propensity score-matched. The complication rate in the SG group was 6.1% (n = 127) as compared to 7.9% (n = 166) in the RYGB group (p = 0.09). And, 702 pairs of OAGB and RYGB were matched. The complication rate in both groups was the same at 7.5 % (n = 53; p = 0.07). Conclusions This global study found no significant difference in the 30-day morbidity and mortality of SG, RYGB, and OAGB in propensity score-matched cohorts.

Robot-assisted versus laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy: a propensity score-matched comparative analysis using the 2015–2016 MBSAQIP database

2018 ◽  
Vol 33 (5) ◽  
pp. 1600-1612 ◽  
Author(s):  
Raul Sebastian ◽  
Melanie H. Howell ◽  
Kai-Hua Chang ◽  
Gina Adrales ◽  
Thomas Magnuson ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Sleeve Gastrectomy ◽  
Comparative Analysis ◽  
Propensity Score ◽  
Robot Assisted

scholarly journals Impact of Nonalcoholic Steatohepatitis on the Outcome of Patients Undergoing Roux-en-Y Gastric Bypass Surgery: a Propensity Score–Matched Analysis

2021 ◽  
Author(s):  
Ziad Abbassi ◽  
Lorenzo Orci ◽  
Jeremy Meyer ◽  
Sebastian Douglas Sgardello ◽  
Nicolas Goossens ◽  
...  
Keyword(s):  
Weight Loss ◽  
Gastric Bypass ◽  
Propensity Score ◽  
Propensity Score Matching ◽  
Nonalcoholic Steatohepatitis ◽  
Hepatocellular Injury ◽  
Nonalcoholic Fatty Liver ◽  
Simple Steatosis ◽  
Metabolic Outcomes

Abstract Purpose It is currently unknown whether NASH (nonalcoholic steatohepatitis), as compared to simple steatosis, is associated with impaired postoperative weight loss and metabolic outcomes after RYGB surgery. To compare the effectiveness of Roux-en-Y gastric bypass (RYGB) on patients with NASH versus those with simple nonalcoholic fatty liver (NAFL). Materials and Methods We retrospectively retrieved data from 515 patients undergoing RYGB surgery with concomitant liver biopsy. Clinical follow-up and metabolic assessment were performed prior to surgery and 12 months after surgery. We used multivariate analysis of variance (MANOVA) and propensity score matching and we assessed for changes in markers of hepatocellular injury and metabolic outcomes. Results There were 421 patients with simple NAFL, and 94 with NASH. Baseline alanine and aspartate aminotransferases were significantly higher in patients with NASH (p < 0.01). Twelve months after the RYGB surgery, as determined by both MANOVA and propensity score matching, patients with NASH exhibited a significantly greater reduction in alanine aminotransferase (ß-coefficient − 12 iU/l [− 22 to − 1.83], 95% CI, adjusted p = 0.021) compared to their NAFL counterparts (31 matched patients in each group with no loss to follow-up at 12 months). Excess weight loss was similar in both groups (ß-coefficient 4.54% [− 3.12 to 12.21], 95% CI, adjusted p = 0.244). Change in BMI was comparable in both groups (− 14 (− 16.6 to − 12.5) versus − 14.3 (− 17.3 to − 11.9), p = 0.784). Conclusion After RYGB surgery, patients with NASH experience a greater reduction in markers for hepatocellular injury and similar weight loss compared to patients with simple steatosis.

Wirkmechanismen der bariatrischen und metabolen Chirurgie

2019 ◽  
Vol 76 (3) ◽  
pp. 123-127
Author(s):  
Hanna Hosa ◽  
Marco Bueter
Keyword(s):  
Gastric Bypass ◽  
Sleeve Gastrectomy

Zusammenfassung. Zusammenfassung: Bei steigender Prävalenz der Adipositas und der damit assoziierten Komorbiditäten rückt die bariatrische und metabole Chirurgie immer mehr in den Vordergrund, wobei weltweit der Roux-Y-Magenbypass (= Roux-en-Y ­Gastric- Bypass, RYGB) und der Schlauchmagen (= Sleeve gastrectomy, SG) die häufigsten Eingriffe darstellen. Der erzielte Gewichtsverlust und das veränderte Essverhalten scheinen dabei nicht wie initial vermutet ausschliesslich auf einer ­mechanischen Restriktion der Nahrungspassage und / oder einer kalorischen Malabsorption der aufgenommenen Nahrung zu beruhen, sondern vielmehr auf ein komplexes Zusammenspiel verschiedenster physiologischer Wirkmechanismen zurückführbar zu sein. Ziel des vorliegenden Artikels ist es deshalb, vor dem Hintergrund des aktuellen Wissenstandes einen kurzen Überblick über die wichtigsten Wirkmechanismen der bariatrischen und metabolen Chirurgie zu liefern.

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