Metal-organic framework-based intelligent drug delivery systems for cancer theranostic: A review

2021 ◽  
Author(s):  
Qingni Xu ◽  
Chaohua Li ◽  
Yuqi Chen ◽  
Yueli Zhang ◽  
Bo Lu
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Metal Organic Framework ◽  
Delivery Systems ◽  
Metal Organic ◽  
Organic Framework

Progress of Stimuli-Responsive Nanoscale Metal Organic Frameworks as Controlled Drug Delivery Systems

2020 ◽  
Vol 17 ◽  
Author(s):  
Ailing Feng ◽  
Yanni Wang ◽  
Jinzi Ding ◽  
Rong Xu ◽  
Xiaodong Li
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
Controlled Drug Delivery ◽  
Delivery Systems ◽  
Stimuli Responsive ◽  
Direct Assembly ◽  
Metal Organic ◽  
Organic Framework

Background: Development of controlled drug delivery systems can improve the pharmacokinetic characteristics of drug molecules in the human body, thereby significantly improving the utilization rate of drugs and reducing toxicity and side effects caused by high concentrations of drugs, which can occur when delivery is not controlled. Metal organic frameworks are a new class of very promising crystalline microporous materials, especially when the size is reduced to the nanometer range. Metal organic frameworks exhibit large specific surface areas, tunable compositions, and easy functionalization. In recent years, increasing number of studies have reported the remarkable advances in multifunctional nanoscale metal organic frameworks in drug delivery. Objective: Review the latest research involving advances in stimuli-responsive nanoscale metal organic frameworks as drug delivery systems in controlled-release drugs. Discussion: We first introduce the two main strategies associated with nanoscale metal organic frameworks used in drug loading: direct assembly and post-encapsulation. We next focus on the latest discoveries of nanoscale metal organic framework-based stimulus response systems for drug delivery, including pH, magnetics, light, ion, temperature, and other stimuli, as well as multiple stimulus-responsive drug delivery systems. Finally, we discuss the challenges and future development directions of nanoscale metal organic framework-based controlled drug release.

Towards rational design of metal-organic framework-based drug delivery systems

2018 ◽  
Vol 87 (9) ◽  
pp. 831-858 ◽  
Author(s):  
A A Simagina ◽  
M V Polynski ◽  
A V Vinogradov ◽  
E A Pidko
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Rational Design ◽  
Metal Organic Framework ◽  
Delivery Systems ◽  
Metal Organic ◽  
Organic Framework

β-Cyclodextrin-based Metal-Organic Framework as a Carrier for Zero-order Drug Delivery

2021 ◽  
pp. 129766
Author(s):  
Yanyi Li ◽  
Haobin Huang ◽  
Chongwei Ding ◽  
Xiaoping Zhou ◽  
Hong Li
Keyword(s):  
Drug Delivery ◽  
Metal Organic Framework ◽  
Zero Order ◽  
Metal Organic ◽  
Organic Framework

scholarly journals Advances in Functional Metal‐Organic Frameworks Based On‐Demand Drug Delivery Systems for Tumor Therapeutics

2021 ◽  
pp. 2100014
Author(s):  
Bhanu Nirosha Yalamandala ◽  
Wei‐Ting Shen ◽  
Sheng‐Hao Min ◽  
Wen‐Hsuan Chiang ◽  
Shing‐Jyh Chang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Metal Organic Frameworks ◽  
Delivery Systems ◽  
On Demand ◽  
Metal Organic

Cytotoxicity of a metal–organic framework: Drug delivery

2017 ◽  
Vol 77 ◽  
pp. 68-71 ◽  
Author(s):  
Aiqing Ma ◽  
Zhidong Luo ◽  
Chuying Gu ◽  
Baohong Li ◽  
Jianqiang Liu
Keyword(s):  
Drug Delivery ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Organic Framework
Sign in / Sign up

Export Citation Format

Share Document