Role of Pelvic Organ Crosstalk in Dysfunction of the Bowel and Bladder

2022 ◽  
Author(s):  
Sanjay Sinha ◽  
Pawan Vasudeva ◽  
Sirish Bharadwaj ◽  
Ankur Mittal
Keyword(s):  
Pelvic Organ ◽  
Organ Crosstalk

scholarly journals Role of different childbirth strategies on pelvic organ prolapse and stress urinary incontinence: a prospective study

2008 ◽  
Vol 121 (3) ◽  
pp. 213-215 ◽  
Author(s):  
Lan ZHU ◽  
Xu-ming BIAN ◽  
Yan LONG ◽  
Jing-he LANG
Keyword(s):  
Urinary Incontinence ◽  
Pelvic Organ Prolapse ◽  
Stress Urinary Incontinence ◽  
Prospective Study ◽  
Pelvic Organ ◽  
A Prospective Study

scholarly journals MP33-05 ROLE OF HYSTERECTOMY AT THE TIME OF NATIVE PELVIC ORGAN PROLAPSE (POP) REPAIR

2018 ◽  
Vol 199 (4S) ◽  
Author(s):  
Bilal Chughtai ◽  
Dominique Thomas ◽  
Jialin Mao ◽  
Tirsit Asfaw ◽  
Jennifer Anger ◽  
...  
Keyword(s):  
Pelvic Organ Prolapse ◽  
Pelvic Organ ◽  
Pop Repair

scholarly journals Role of Magnetic Resonance defecography in assessment of pelvic floor dysfunction

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
M S Moussa ◽  
Y I Abdelkhaleq ◽  
S M Botros ◽  
A A Montasser
Keyword(s):  
Pelvic Organ Prolapse ◽  
Physical Examination ◽  
Pelvic Floor ◽  
Pelvic Floor Dysfunction ◽  
Pelvic Organ ◽  
Magnetic Resonance Defecography ◽  
Facial Defect ◽  
Floor Failure ◽  
Muscle Tear

Abstract Purpose to assess the role of the role of MR defecography in assessment of pelvic floor failure . Methods and Material Thirty-six patients (twenty-seven female and nine male) with female and male patients, complaining of stress urinary incontinence, constipation, fecal incontinence or pelvic organ prolapse. Results MRI revealed 18 cystocele (50%), compared to physical examination 2 cases(5.6%),MRI revealed 28 rectocele ( 77.8%) compared to physical examination that showed 13 (36.1%) , MRI revealed 10 uterine descent (40.7%), compared to physical examination 6 (22.2%) I, MRI revealed 7 enterocele (19.4%) compared to physical examination that was negative. MRI revealed level I/II facial defect in and level III facial defect in, 19 cases of Intussusception (52.8%), urethral hypermobility in 14 (38.9%), sphincteric defect 7 (19.4%), levator angle weakness in 30 cases (83.3%), iliococcygeaus muscle tear in 5 cases (13.9%), puborectalis tear in 3 cases (8.3%),anorectal decent in 26 cases (72.2%), genital hiatus width in 23 (63.9%) Conclusion Dynamic MR imaging is a necessary tool in the diagnosis of multicompartment pelvic organ prolapse and it provides good concordance with clinical examination

Organ crosstalk: the role of the kidney

2010 ◽  
Vol 16 (2) ◽  
pp. 180 ◽  
Author(s):  
&NA;
Keyword(s):  
Organ Crosstalk

scholarly journals Urodynamic Changes in Pelvic Organ Prolapse and the Role of Surgery

2009 ◽  
Vol 65 (3) ◽  
pp. 221-224
Author(s):  
R Panicker ◽  
S Srinivas
Keyword(s):  
Pelvic Organ Prolapse ◽  
Pelvic Organ

scholarly journals Role of lysyl oxidase like 1 in regulation of postpartum connective tissue metabolism in the mouse vagina†

2019 ◽  
Vol 101 (5) ◽  
pp. 916-927 ◽  
Author(s):  
Ali Borazjani ◽  
Bruna M Couri ◽  
Mei Kuang ◽  
Brian M Balog ◽  
Margot S Damaser
Keyword(s):  
Gene Expression ◽  
Enzyme Activity ◽  
Connective Tissue ◽  
Lysyl Oxidase ◽  
Gelatin Zymography ◽  
Pelvic Organ ◽  
Tissue Metabolism ◽  
Reverse Transcription Pcr ◽  
Connective Tissue Metabolism

Abstract Pelvic organ prolapse (POP) in lysyl oxidase like-1 knockout (Loxl1 KO) mice occurs primarily in parous mice and is rare in nulliparous mice. We determined the effect of Loxl1 deficiency on postpartum regulation of connective tissue metabolism genes and degradative enzyme activity in the vagina at 20 days gestation or 4 h, 48 h, 7 days, 15 days, 25 days, 7 weeks, or 12 weeks postpartum. Nulliparous Loxl1 KO and wildtype (WT) mice aged 11, 18, or 23 weeks were controls. Gene expression and enzyme activity were assessed using real-time quantitative reverse transcription PCR and fluorescein conjugated gelatin zymography, respectively. Parity, but not aging, had a significant influence on gene expression both with time postpartum and between KO and WT mice. Mmp2, Timp1, Timp2, Timp3, Timp4, Col1a1, Col3a1, Acta2, and Bmp1 were differentially expressed between KO and WT mice. Correlational analysis of gene-gene pairs revealed 10 significant differences between parous KO and WT groups, 5 of which were due to lack of co-expression of Bmp1 in KO mice. The overall enzyme activity that could be attributed to MMPs was significantly higher in WT compared to KO mice both 25 days and 12 weeks postpartum, and MMP activity was significantly lower 15 days and 25 days postpartum compared to KO nulliparous controls, but not WT. These findings suggest that Loxl1 deficiency combined with parity has a significant impact on postpartum regulation of connective tissue metabolism, particularly as it relates to co-expression of Bmp1 and altered proteolytic activity.

scholarly journals The role of transforming growth factor-ß (TGF-ß1) in postmenopausal women with pelvic organ prolapse: An immunohistochemical study

2020 ◽  
Vol 7 ◽  
pp. 100111
Author(s):  
Greta Lisa Carlin ◽  
Klaus Bodner ◽  
Oliver Kimberger ◽  
Peter Haslinger ◽  
Christian Schneeberger ◽  
...  
Keyword(s):  
Pelvic Organ Prolapse ◽  
Growth Factor ◽  
Postmenopausal Women ◽  
Transforming Growth Factor ◽  
Immunohistochemical Study ◽  
Pelvic Organ

Organ crosstalk: the role of the kidney

2009 ◽  
Vol 15 (6) ◽  
pp. 481-487 ◽  
Author(s):  
Xiang Li ◽  
Heitham T Hassoun ◽  
Rachel Santora ◽  
Hamid Rabb
Keyword(s):  
Organ Crosstalk

scholarly journals Frailty and the Role of Obliterative versus Reconstructive Surgery for Pelvic Organ Prolapse: A National Study

2017 ◽  
Vol 197 (6) ◽  
pp. 1502-1506 ◽  
Author(s):  
Anne M. Suskind ◽  
Chengshi Jin ◽  
Louise C. Walter ◽  
Emily Finlayson
Keyword(s):  
Pelvic Organ Prolapse ◽  
Reconstructive Surgery ◽  
Pelvic Organ ◽  
National Study
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