Management of Advanced Heart Failure due to Cancer Therapy: the Present Role of Mechanical Circulatory Support and Cardiac Transplantation

2015 ◽  
Vol 17 (6) ◽  
Author(s):  
Salil V. Deo ◽  
Sadeer G. Al-Kindi ◽  
Guilherme H. Oliveira
Keyword(s):  
Heart Failure ◽  
Cancer Therapy ◽  
Cardiac Transplantation ◽  
Mechanical Circulatory Support ◽  
Advanced Heart Failure ◽  
Circulatory Support ◽  
Present Role

scholarly journals The role of long-term mechanical circulatory support in patients with advanced heart failure

2020 ◽  
Vol 28 (S1) ◽  
pp. 115-121
Author(s):  
S. E. A. Felix ◽  
N. de Jonge ◽  
K. Caliskan ◽  
O. Birim ◽  
K. Damman ◽  
...  
Keyword(s):  
Heart Failure ◽  
Mechanical Circulatory Support ◽  
Advanced Heart Failure ◽  
Circulatory Support

scholarly journals Mechanical Circulatory Support for Advanced Heart Failure

Circulation ◽  
2003 ◽  
Vol 108 (25) ◽  
pp. 3064-3068 ◽  
Author(s):  
O.H. Frazier ◽  
Reynolds M. Delgado
Keyword(s):  
Heart Failure ◽  
Mechanical Circulatory Support ◽  
Advanced Heart Failure ◽  
Circulatory Support

scholarly journals Treatment of Advanced Heart Failure—Focus on Transplantation and Durable Mechanical Circulatory Support

2021 ◽  
Vol 17 (4) ◽  
pp. 697-708
Author(s):  
Federica Guidetti ◽  
Mattia Arrigo ◽  
Michelle Frank ◽  
Fran Mikulicic ◽  
Mateusz Sokolski ◽  
...  
Keyword(s):  
Heart Failure ◽  
Mechanical Circulatory Support ◽  
Advanced Heart Failure ◽  
Circulatory Support

scholarly journals Advanced Heart Failure

2019 ◽  
Vol 16 (6) ◽  
pp. 47-57
Author(s):  
Leonida Gherasim
Keyword(s):  
Heart Failure ◽  
Mechanical Circulatory Support ◽  
Implantable Defibrillator ◽  
Advanced Heart Failure ◽  
Cardiac Resynchronization ◽  
Circulatory Support ◽  
Cardiac Transplant ◽  
Results Of Treatment ◽  
Cardiac Devices ◽  
Advanced Therapy

AbstractAdvanced heart failure (AHF) is the stage of heart failure (HF) refractory to maximal medical treatment, cardiac devices (CRT - cardiac resynchronization, ICD - implantable defibrillator) and surgical treatment. AHF has become of interest through the experience and favorable results of treatment by mechanical circulatory support (MCS) and cardiac transplant (CT). The article reviews the criteria for defining the AHF (2018 ESC statement), natural history and prognosis outside the advanced treatment forms. Evaluation of risk and prognostic factors is required before the decision of advanced therapy: clinical factors (HF severity and reduction of cardiorespiratory functional capacity), RV function, biological markers and elements of organ dysfunction, as well as reduction of tolerance to conventional medication.Finally, the principles of treatment and the results of mechanical circulatory support and cardiac transplant are presented.

The future of mechanical circulatory support for advanced heart failure

2016 ◽  
Vol 31 (3) ◽  
pp. 321-328 ◽  
Author(s):  
Karolina K. Marinescu ◽  
Nir Uriel ◽  
Sirtaz Adatya
Keyword(s):  
Heart Failure ◽  
Mechanical Circulatory Support ◽  
Advanced Heart Failure ◽  
Circulatory Support ◽  
The Future

Abstract 15170: In-hospital Utilization and Outcomes of Palliative Care Consultation in Patients With Advanced Heart Failure Complicated by Cardiogenic Shock Requiring Mechanical Circulatory Support

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Jelani Grant ◽  
Louis Vincent ◽  
Bertrand Ebner ◽  
Jennifer Maning ◽  
Igor Vaz ◽  
...  
Keyword(s):  
Heart Failure ◽  
Palliative Care ◽  
Cardiogenic Shock ◽  
Mechanical Circulatory Support ◽  
Life Experiences ◽  
Advanced Heart Failure ◽  
Circulatory Support ◽  
High Morbidity ◽  
Palliative Care Consultation ◽  
Care Consultation

Introduction: Hospitalizations associated with advanced heart failure (HF) requiring mechanical circulatory support (MCS) are usually associated with a high morbidity, mortality and a protracted hospital course. Prior studies have shown that the early inclusion of palliative care specialist is associated with better end-of-life experiences. Methods: The National Inpatient Sample Database was queried from 2012 to 2017 for relevant International Classification of Diseases (ICD)-9 and ICD-10 procedural and diagnostic codes to identify patients above 18 years with advanced HF admitted with cardiogenic shock requiring MCS. Baseline characteristics and in-hospital outcomes were compared among patients evaluated by palliative care and those who were not. A p-value of <0.001 was considered statistically significant. Results: There were 748,360 patients hospitalized for advanced HF complicated by cardiogenic shock requiring MCS, of these a palliative care consult was placed in 118,015 (15.8%) patients. Patients evaluated by palliative care were older (70.6±14.9 vs. 64.9±16.3 years old, p<0.001) and had a higher prevalence of atrial fibrillation (39.3 vs. 35.1%,p<0.001) and chronic kidney disease (40.4 vs. 33.3, p<0.001), however had lower hypertension (57.4 vs. 59.7%, p<0.001), diabetes (35.4 vs. 36.5%, p<0.001), coronary artery disease (51.2 vs. 58.4%, p<0.001) and acute coronary syndromes (39.2 vs. 45.0%, p<0.001). Consulting palliative care was associated with a shorter length of stay (8.8±12.0 vs. 11.9±15.5 days, p<0.001), lower total hospital cost ($161,972±265,156 vs. $219,114±318,387, p<0.001) and higher Do Not Resuscitate (DNR) orders (30.8 vs. 5.8%, p<0.001). Mortality rates were higher in the palliative care cohort (73.4 vs. 29.4%, p<0.001). Conclusions: Despite the high morbidity and mortality associated with advanced HF patients with cardiogenic shock requiring MCS, the overall prevalence of palliative care consultation is exceedingly low. DNR orders were more prevalent in patients seen by the palliative care service. This study highlights the underutilization of palliative care services in this patient population, precluding any perceived benefit in end of life experiences.

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