Injury Complexity Factors Predict Heterotopic Ossification Restricting Motion After Elbow Trauma

Jimme K. Wiggers; Gijs T. T. Helmerhorst; Kim M. Brouwer; Maarten C. Niekel; Fiesky Nunez; David Ring

doi:10.1007/s11999-013-3304-0

Injury Complexity Factors Predict Heterotopic Ossification Restricting Motion After Elbow Trauma

Clinical Orthopaedics and Related Research ◽

10.1007/s11999-013-3304-0 ◽

2013 ◽

Vol 472 (7) ◽

pp. 2162-2167 ◽

Cited By ~ 20

Author(s):

Jimme K. Wiggers ◽

Gijs T. T. Helmerhorst ◽

Kim M. Brouwer ◽

Maarten C. Niekel ◽

Fiesky Nunez ◽

...

Keyword(s):

Heterotopic Ossification ◽

Elbow Trauma

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Serum uric acid level is associated with the incidence of heterotopic ossification following elbow trauma surgery

Journal of Shoulder and Elbow Surgery ◽

10.1016/j.jse.2020.01.071 ◽

2020 ◽

Vol 29 (5) ◽

pp. 996-1001

Author(s):

Jinwu Bai ◽

Zhihui Kuang ◽

Yimin Chen ◽

Kai Hang ◽

Jianxiang Xu ◽

...

Keyword(s):

Uric Acid ◽

Heterotopic Ossification ◽

Serum Uric Acid ◽

Uric Acid Level ◽

Acid Level ◽

Serum Uric Acid Level ◽

Trauma Surgery ◽

Elbow Trauma

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Radiation Therapy for Heterotopic Ossification Prophylaxis Acutely After Elbow Trauma: A Prospective Randomized Study

Yearbook of Hand and Upper Limb Surgery ◽

10.1016/j.yhls.2011.04.086 ◽

2011 ◽

Vol 2011 ◽

pp. 148-149

Author(s):

M.I. Loebenberg

Keyword(s):

Radiation Therapy ◽

Heterotopic Ossification ◽

Randomized Study ◽

Prospective Randomized Study ◽

Elbow Trauma

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Comparing Options for Heterotopic Ossification Prophylaxis following Elbow Trauma: A Systematic Review and Meta-Analysis

Journal of Hand and Microsurgery ◽

10.1055/s-0040-1721880 ◽

2020 ◽

Author(s):

Jeffrey M. Henstenburg ◽

Matthew Sherman ◽

Asif M. Ilyas

Keyword(s):

Systematic Review ◽

Heterotopic Ossification ◽

Meta Analysis ◽

Traumatic Injury ◽

Final Analysis ◽

Patient Characteristics ◽

Cochrane Library ◽

Level Of Evidence ◽

Elbow Trauma ◽

Radiation Group

Abstract Introduction Heterotopic ossification (HO) can be a potentially serious and devastating complication following traumatic injury to the elbow. HO prophylaxis options include nonsteroidal anti-inflammatory drugs (NSAIDs) and radiation therapy (RT) but neither has been proven more effective. The purpose of this review is to compare effectiveness and outcomes between NSAID and RT prophylaxis for HO about the elbow following a traumatic injury. Materials and Methods We performed a systematic review of PubMed and Cochrane Library for cases of HO prophylaxis following elbow trauma utilizing PRISMA guidelines to determine the most effective form of prophylaxis. Outcomes of interest included recurrence of HO, range of motion (ROM), and Mayo elbow performance index (MEPI). A total of 36 articles and 826 elbows of which 203 received RT and 623 received NSAID were identified and included in the final analysis. Results Rates of HO formation or recurrence following elbow trauma were similar between radiation and NSAID prophylaxis (15.6% vs. 22.2%, respectively p = 0.457). ROM was similar in flexion and extension arc (109.0 degrees in radiation vs. 112.8 in NSAIDs, p = 0.459) and in pronation and supination arc (118.9 degrees radiation vs. 134.7 degrees NSAIDs, p = 0.322). MEPI scores were 79.19 in the radiation group and 88.82 in the NSAIDs group at the final follow-up. Conclusion There is no statistical difference in HO development, recurrence, or final ROM between NSAIDs and RT prophylaxis following trauma to the elbow. We recommend the choice of modality based on patient characteristics, cost, and surgeon preference. Level of Evidence Level III.

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