“One-Off” Complete Radiofrequency Ablation for Hepatocellular Carcinoma in a “High-Risk Location” Adjacent to the Major Bile Duct and Hepatic Blood Vessel

Hepatocellular carcinoma (HCC) is strongly associated with cirrhosis. High-risk groups include those with hepatitis due to hepatitis B (HBV) or C (HCV) virus. This chapter provides an algorithm for investigating liver nodules in order to diagnose hepatocellular carcinoma. It explores surgical options including resection, liver transplantation, and minimally invasive options, such as radiofrequency ablation. Palliative options are described and an algorithm for the treatment of HCC is presented. The chapter also discusses hepatic hydatid disease, caused by the metacestode stages of Echinococcus granulosus and E. multilocularis.

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Combining radiofrequency ablation and ethanol injection may achieve comparable long-term outcomes in larger hepatocellular carcinoma (3.1–4 cm) and in high-risk locations

The Kaohsiung Journal of Medical Sciences ◽

10.1016/j.kjms.2014.04.006 ◽

2014 ◽

Vol 30 (8) ◽

pp. 396-401 ◽

Cited By ~ 6

Author(s):

Ji-Wei Lin ◽

Chen-Chun Lin ◽

Wei-Ting Chen ◽

Shi-Ming Lin

Keyword(s):

Hepatocellular Carcinoma ◽

Radiofrequency Ablation ◽

High Risk ◽

Long Term Outcomes ◽

Ethanol Injection

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Iodine-125 Brachytherapy Prophylaxis after Radiofrequency Ablation Cannot Benefit Patients in High Risk of Locoregional Hepatocellular Carcinoma Recurrence

Scientific Reports ◽

10.1038/s41598-017-03831-5 ◽

2017 ◽

Vol 7 (1) ◽

Cited By ~ 2

Author(s):

Jian-Fei Tu ◽

Ya-Hui Ding ◽

Li Chen ◽

Xi-Hui Ying ◽

Deng-Ke Zhang ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Radiofrequency Ablation ◽

High Risk ◽

Hepatocellular Carcinoma Recurrence ◽

Iodine 125

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A Simple Method to Avoid Bile Duct Injury during Percutaneous Radiofrequency Ablation Therapy for Hepatocellular Carcinoma

Case Reports in Oncology ◽

10.1159/000510043 ◽

2020 ◽

Vol 13 (3) ◽

pp. 1337-1342

Author(s):

Hidetaka Takashima ◽

Michihisa Moriguchi ◽

Natsuko Hayashi ◽

Kyohei Ikeda ◽

Kiyoshi Ogiso ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Radiofrequency Ablation ◽

Bile Duct ◽

Bile Duct Injury ◽

Bile Ducts ◽

Adverse Outcomes ◽

Anatomical Location ◽

Simple Method ◽

Ablation Therapy ◽

Radiofrequency Ablation Therapy

Hepatocellular carcinoma represents a major global health burden. Its treatment is often complicated by the anatomical location of tumors, which can lead to adverse outcomes. Radiofrequency ablation has recently gained attention as a safe method for treating hepatocellular carcinoma, but only in tumors that are not adjacent to bile ducts. Here, we report a new method for cooling the bile duct during radiofrequency ablation therapy, in which the outer jacket of an elastor needle was fixed and flash-cooled with chilled saline. This method was applied in a patient with hepatocellular carcinoma tumors near the main bile duct. The patient underwent successful radiofrequency ablation with bile duct cooling. The advantages of this method include low medical cost, simpler securing of nonexpanded bile ducts, and simultaneous removal upon termination of the radiofrequency ablation therapy. Bile duct complications associated with radiofrequency ablation typically have delayed onset. Computed tomography examination 2 months after treatment showed no bile duct injury in this case.

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