Comparison of Reprogramming Genes in Induced Pluripotent Stem Cells and Nuclear Transfer Cloned Embryos

2014 ◽  
Vol 10 (4) ◽  
pp. 548-560 ◽  
Author(s):  
Lian Duan ◽  
Zhendong Wang ◽  
Jingling Shen ◽  
Zhiyan Shan ◽  
Xinghui Shen ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Nuclear Transfer ◽  
Induced Pluripotent

scholarly journals Ovine Induced Pluripotent Stem Cells Are Resistant to Reprogramming after Nuclear Transfer

2015 ◽  
Vol 17 (1) ◽  
pp. 19-27 ◽  
Author(s):  
Sergio D. German ◽  
Keith H.S. Campbell ◽  
Elisabeth Thornton ◽  
Gerry McLachlan ◽  
Dylan Sweetman ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Nuclear Transfer ◽  
Induced Pluripotent

scholarly journals Successful generation of cloned mice using nuclear transfer from induced pluripotent stem cells

Cell Research ◽  
2010 ◽  
Vol 20 (7) ◽  
pp. 850-853 ◽  
Author(s):  
Shuya Zhou ◽  
Chenhui Ding ◽  
Xiaoyang Zhao ◽  
Eryao Wang ◽  
Xiangpeng Dai ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Nuclear Transfer ◽  
Induced Pluripotent

Reprogramming of Somatic Cells After Fusion With Induced Pluripotent Stem Cells and Nuclear Transfer Embryonic Stem Cells

2010 ◽  
Vol 19 (2) ◽  
pp. 239-246 ◽  
Author(s):  
Huseyin Sumer ◽  
Karen L. Jones ◽  
Jun Liu ◽  
Corey Heffernan ◽  
Pollyanna A. Tat ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Nuclear Transfer ◽  
Somatic Cells ◽  
Embryonic Stem ◽  
Induced Pluripotent

scholarly journals Enhanced Telomere Rejuvenation in Pluripotent Cells Reprogrammed via Nuclear Transfer Relative to Induced Pluripotent Stem Cells

2014 ◽  
Vol 14 (1) ◽  
pp. 27-39 ◽  
Author(s):  
Rongrong Le ◽  
Zhaohui Kou ◽  
Yonghua Jiang ◽  
Ming Li ◽  
Bo Huang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Nuclear Transfer ◽  
Pluripotent Cells ◽  
Induced Pluripotent

scholarly journals Establishment of porcine nuclear transfer-derived embryonic stem cells using induced pluripotent stem cells as donor nuclei

2020 ◽  
Vol 66 (2) ◽  
pp. 163-174
Author(s):  
Seiki HARAGUCHI ◽  
Thanh Quang DANG-NGUYEN ◽  
David WELLS ◽  
Daiichiro FUCHIMOTO ◽  
Tomokazu FUKUDA ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Nuclear Transfer ◽  
Embryonic Stem ◽  
Induced Pluripotent

scholarly journals Silencing of retrotransposon-derived imprinted gene RTL1 is the main cause for postimplantational failures in mammalian cloning

2018 ◽  
Vol 115 (47) ◽  
pp. E11071-E11080 ◽  
Author(s):  
Dawei Yu ◽  
Jing Wang ◽  
Huiying Zou ◽  
Tao Feng ◽  
Lei Chen ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Nuclear Transfer ◽  
Fetal Loss ◽  
Epigenetic Mechanism ◽  
Imprinted Genes ◽  
Pregnancy Failure ◽  
Induced Pluripotent

Substantial rates of fetal loss plague all in vitro procedures involving embryo manipulations, including human-assisted reproduction, and are especially problematic for mammalian cloning where over 90% of reconstructed nuclear transfer embryos are typically lost during pregnancy. However, the epigenetic mechanism of these pregnancy failures has not been well described. Here we performed methylome and transcriptome analyses of pig induced pluripotent stem cells and associated cloned embryos, and revealed that aberrant silencing of imprinted genes, in particular the retrotransposon-derived RTL1 gene, is the principal epigenetic cause of pregnancy failure. Remarkably, restoration of RTL1 expression in pig induced pluripotent stem cells rescued fetal loss. Furthermore, in other mammals, including humans, low RTL1 levels appear to be the main epigenetic cause of pregnancy failure.

Directed differentiation of mouse-induced pluripotent stem cells generates dopaminergic nerve

2010 ◽  
Vol 34 (8) ◽  
pp. S36-S36
Author(s):  
Ping Duan ◽  
Xuelin Ren ◽  
Wenhai Yan ◽  
Xuefei Han ◽  
Xu Yan ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Directed Differentiation ◽  
Induced Pluripotent
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