Three-dimensional Spheroid Culture Enhances Multipotent Differentiation and Stemness Capacities of Human Dental Pulp‐derived Mesenchymal Stem Cells by Modulating MAPK and NF-kB Signaling Pathways

2021 ◽  
Author(s):  
Ya-Hui Chan ◽  
Yu-Chieh Lee ◽  
Chia-Yi Hung ◽  
Pi-Ju Yang ◽  
Pin-Chuang Lai ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Signaling Pathways ◽  
Dental Pulp ◽  
Three Dimensional ◽  
Spheroid Culture ◽  
Human Dental Pulp ◽  
Multipotent Differentiation

scholarly journals Three Dimensional Spheroid Culture of Canine Amniotic Fluid Derived Mesenchymal Stem Cells Enhances Differentiation Efficacycy

2015 ◽  
Vol 60 (2) ◽  
pp. 377-384
Author(s):  
Yu Na Ha ◽  
Ju Lan Chun ◽  
Eun Young Kim ◽  
Ji Hey Lee ◽  
Bo Myoung Lee ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Amniotic Fluid ◽  
Three Dimensional ◽  
Spheroid Culture

The performance of human dental pulp stem cells on different three-dimensional scaffold materials

Biomaterials ◽  
2006 ◽  
Vol 27 (33) ◽  
pp. 5658-5668 ◽  
Author(s):  
Weibo Zhang ◽  
X. Frank Walboomers ◽  
Toin H. van Kuppevelt ◽  
Willeke F. Daamen ◽  
Zhuan Bian ◽  
...  
Keyword(s):  
Stem Cells ◽  
Dental Pulp ◽  
Three Dimensional ◽  
Dental Pulp Stem Cells ◽  
Human Dental Pulp ◽  
Scaffold Materials

scholarly journals Noncoding RNAs: new insights into the odontogenic differentiation of dental tissue-derived mesenchymal stem cells

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Fuchun Fang ◽  
Kaiying Zhang ◽  
Zhao Chen ◽  
Buling Wu
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Signaling Pathways ◽  
Dental Pulp ◽  
Noncoding Rnas ◽  
Long Noncoding Rnas ◽  
Substantial Part ◽  
Dental Tissue ◽  
Odontogenic Differentiation ◽  
Dentin Regeneration

Abstract Odontoblasts are cells that contribute to the formation of the dental pulp complex. The differentiation of dental tissue-derived mesenchymal stem cells into odontoblasts comprises many factors and signaling pathways. Noncoding RNAs (ncRNAs), comprising a substantial part of poly-A tail mature RNAs, are considered “transcriptional noise.” Emerging evidence has shown that ncRNAs have key functions in the differentiation of mesenchymal stem cells. In this review, we discussed two major types of ncRNAs, including microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), in terms of their role in the odontogenic differentiation of dental tissue-derived stem cells. Recent findings have demonstrated important functions for miRNAs and lncRNAs in odontogenic differentiation. It is expected that ncRNAs will become promising therapeutic targets for dentin regeneration based on stem cells.

scholarly journals Development of an antibacterial nanocomposite hydrogel for human dental pulp engineering

2020 ◽  
Vol 8 (36) ◽  
pp. 8422-8432
Author(s):  
M. Bekhouche ◽  
M. Bolon ◽  
F. Charriaud ◽  
M. Lamrayah ◽  
D. Da Costa ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Dental Pulp ◽  
Nanocomposite Hydrogel ◽  
Human Dental Pulp

Nanocomposite fibrin-based hydrogel with antibacterial and antibiofilm properties, safe for dental pulp mesenchymal stem cells.

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