Decompressive Hemicraniectomy in Malignant Middle Cerebral Artery Infarct: A Randomized Controlled Trial Enrolling Patients up to 80 Years Old

2012 ◽  
Vol 17 (2) ◽  
pp. 161-171 ◽  
Author(s):  
Jingwei Zhao ◽  
Ying Ying Su ◽  
Yan Zhang ◽  
Yun Zhou Zhang ◽  
Ruilin Zhao ◽  
...  
Stroke ◽  
2012 ◽  
Vol 43 (12) ◽  
pp. 3284-3290 ◽  
Author(s):  
Zhongrong Miao ◽  
Lidan Jiang ◽  
Hao Wu ◽  
Yuhai Bao ◽  
Liqun Jiao ◽  
...  

Author(s):  
Bulent Gulensoy ◽  
Mete Karatay ◽  
Yavuz Erdem ◽  
Haydar Celik ◽  
Tuncer Tascioglu ◽  
...  

2011 ◽  
Vol 30 (6) ◽  
pp. E18 ◽  
Author(s):  
Omar M. Arnaout ◽  
Salah G. Aoun ◽  
H. Hunt Batjer ◽  
Bernard R. Bendok

Malignant middle cerebral artery stroke carries a very poor prognosis. Significant retrospective data support the hypothesis that decompressive hemicraniectomy decreases mortality rates due to this disease entity. Recently, 3 randomized controlled studies have been published and shed light on these issues and enhance the quality of evidence revolving around this procedure. In this review, the rationale, risks, benefits, and unanswered questions related to hemicraniectomy for acute ischemic stroke are reviewed with an emphasis on how 3 randomized trials have influenced knowledge on this life-saving yet controversial procedure. Further randomized studies are needed to clarify lingering questions regarding age indications and impact on quality of life.


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