Corticospinal Motor Circuit Plasticity After Spinal Cord Injury: Harnessing Neuroplasticity to Improve Functional Outcomes

Author(s):  
Syed Faraz Kazim ◽  
Christian A. Bowers ◽  
Chad D. Cole ◽  
Samantha Varela ◽  
Zafar Karimov ◽  
...  
Author(s):  
Gijs J. A. Willinge ◽  
Falco Hietbrink ◽  
Luke P. H. Leenen

Abstract Background Cricothyroidotomy and surgical tracheostomy are methods to secure airway patency. In emergency surgery, these methods are nowadays mostly reserved for patients unsuited for percutaneous procedures. Detailed description of complications and functional outcomes following both procedures is underreported in current literature. The aim of this study was to evaluate outcomes following cricothyroidotomy and tracheostomy in this presumed complex population. Methods In this retrospective cohort study, adult emergency surgical patients treated with cricothyroidotomy and/or surgical tracheostomy were included. Postoperative complications and functional outcomes in trauma and non-trauma patients were evaluated. Results Forty-one trauma patients and 11 non-trauma emergency surgical patients (mainly after elective onco-abdominal or vascular surgery) were included. Of 52 patients, seven underwent cricothyroidotomy pre-tracheostomy. Mortality was higher in non-trauma patients (p = 0.04) following both procedures. Over half of patients (56%, n = 29) regained unsupported airway patency with a tendency toward increased tracheostomy removal in trauma patients. Among complications, only pneumonia occurred frequently (60%, n = 31), with no relation to patient type. Other complications included local infection (5.8%, n = 4) and wound dehiscence (1.9%, n = 1). Adverse functional outcomes were frequently observed and were mild and self-limiting. Cervical spinal cord injury reduced overall unsupported airway patency (p = 0.01); with high cervical spinal cord injury related to adverse functional outcomes and increased home ventilation need. Conclusions No major procedure-related complications or functional adverse events were encountered following cricothyroidotomy and surgical tracheostomy, even though only complex patients were included. Only mild, self-limiting functional problems occurred, especially in trauma patients with cervical injury who underwent early tracheostomy by longitudinal incision. This information can aid clinicians in making tailor-made decisions for individual patients.


2014 ◽  
Vol 20 (3) ◽  
pp. 225-235 ◽  
Author(s):  
Melissa Nott ◽  
Ian Baguley ◽  
Roxana Heriseanu ◽  
Gerard Weber ◽  
James Middleton ◽  
...  

2017 ◽  
Vol 98 (10) ◽  
pp. e131-e132
Author(s):  
Timothy Belliveau ◽  
Subramani Seetharama ◽  
Jeffrey Axt ◽  
Alan Jette ◽  
David Rosenblum ◽  
...  

2019 ◽  
Vol 100 (10) ◽  
pp. 1924-1931
Author(s):  
Pengsheng Ni ◽  
M.J. Mulcahey ◽  
Mary D. Slavin ◽  
Christina Calhoun Thielen ◽  
Lawrence C. Vogel ◽  
...  

2014 ◽  
Vol 95 (10) ◽  
pp. e80
Author(s):  
Denise Fyffe ◽  
Claire Kalpakjian ◽  
Mary Slavin ◽  
Pamela Kisala ◽  
Steven Kirshblum ◽  
...  

Spine ◽  
2001 ◽  
Vol 26 (Supplement) ◽  
pp. S137-S145 ◽  
Author(s):  
Anthony S. Burns ◽  
John F. Ditunno

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