Preparation, quality control and biodistribution assessment of 153Sm-BPAMD as a novel agent for bone pain palliation therapy

2015 ◽  
Vol 29 (10) ◽  
pp. 870-876 ◽  
Author(s):  
Ali Rabie ◽  
Razieh Enayati ◽  
Hassan Yousefnia ◽  
Amir Reza Jalilian ◽  
Mojtaba Shamsaei ◽  
...  
Keyword(s):  
Quality Control ◽  
Bone Pain ◽  
Pain Palliation ◽  
Bone Pain Palliation ◽  
Novel Agent

Production, quality control, and determination of human absorbed dose of no carrier added177Lu-risedronate for bone pain palliation therapy

2016 ◽  
Vol 60 (1) ◽  
pp. 20-29
Author(s):  
Nafise Salek ◽  
Mohsen Mehrabi ◽  
Simindokht Shirvani Arani ◽  
Ali Bahrami Samani ◽  
Mostafa Erfani ◽  
...  
Keyword(s):  
Quality Control ◽  
Bone Pain ◽  
Absorbed Dose ◽  
Production Quality ◽  
Pain Palliation ◽  
Production Quality Control ◽  
Bone Pain Palliation

Production, quality control and pharmacokinetic studies of 177Lu–zoledronate for bone pain palliation therapy

2013 ◽  
Vol 298 (2) ◽  
pp. 1273-1281 ◽  
Author(s):  
Mirsaeed Nikzad ◽  
Amir R. Jalilian ◽  
Simindokht Shirvani-Arani ◽  
Ali Bahrami-Samani ◽  
Hamid Golchoubian
Keyword(s):  
Quality Control ◽  
Bone Pain ◽  
Production Quality ◽  
Pharmacokinetic Studies ◽  
Pain Palliation ◽  
Production Quality Control ◽  
Bone Pain Palliation

186Re-1,4,8,11-tetraaza cyclotetradecyl-1,4,8,11-tetramethylene phosphonic acid: a novel agent for possible use in metastatic bone-pain palliation

2001 ◽  
Vol 28 (6) ◽  
pp. 709-717 ◽  
Author(s):  
Kanchan Kothari ◽  
Grace Samuel ◽  
Sharmila Banerjee ◽  
P.R Unni ◽  
H.D Sarma ◽  
...  
Keyword(s):  
Phosphonic Acid ◽  
Bone Pain ◽  
Pain Palliation ◽  
Bone Pain Palliation ◽  
Metastatic Bone Pain ◽  
Novel Agent

Metastatic bone pain palliation with 89‐Sr and 186‐Re‐HEDP in breast cancer patients

2001 ◽  
Vol 66 (2) ◽  
pp. 101-109 ◽  
Author(s):  
Rosa Sciuto ◽  
Anna Festa ◽  
Rosella Pasqualoni ◽  
Alessandro Semprebene ◽  
Sandra Rea ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Bone Pain ◽  
Pain Palliation ◽  
Breast Cancer Patients ◽  
Bone Pain Palliation ◽  
Metastatic Bone Pain

scholarly journals Targeted Palliative Radionuclide Therapy for Metastatic Bone Pain

2020 ◽  
Vol 9 (8) ◽  
pp. 2622 ◽  
Author(s):  
Reyhaneh Manafi-Farid ◽  
Fardad Masoumi ◽  
Ghasemali Divband ◽  
Bahare Saidi ◽  
Bahar Ataeinia ◽  
...  
Keyword(s):  
Radionuclide Therapy ◽  
Bone Pain ◽  
Response Rate ◽  
Pain Palliation ◽  
Simultaneous Treatment ◽  
Bone Pain Palliation ◽  
Wide Range ◽  
Metastatic Bone Pain ◽  
Multiple Bone Metastases

Bone metastasis develops in multiple malignancies with a wide range of incidence. The presence of multiple bone metastases, leading to a multitude of complications and poorer prognosis. The corresponding refractory bone pain is still a challenging issue managed through multidisciplinary approaches to enhance the quality of life. Radiopharmaceuticals are mainly used in the latest courses of the disease. Bone-pain palliation with easy-to-administer radionuclides offers advantages, including simultaneous treatment of multiple metastatic foci, the repeatability and also the combination with other therapies. Several β¯- and α-emitters as well as pharmaceuticals, from the very first [89Sr]strontium-dichloride to recently introduced [223Ra]radium-dichloride, are investigated to identify an optimum agent. In addition, the combination of bone-seeking radiopharmaceuticals with chemotherapy or radiotherapy has been employed to enhance the outcome. Radiopharmaceuticals demonstrate an acceptable response rate in pain relief. Nevertheless, survival benefits have been documented in only a limited number of studies. In this review, we provide an overview of bone-seeking radiopharmaceuticals used for bone-pain palliation, their effectiveness and toxicity, as well as the results of the combination with other therapies. Bone-pain palliation with radiopharmaceuticals has been employed for eight decades. However, there are still new aspects yet to be established.

177Lu-Labeled Agents for Neuroendocrine Tumor Therapy and Bone Pain Palliation in Uruguay

2015 ◽  
Vol 9 (1) ◽  
pp. 85-93 ◽  
Author(s):  
Henia Balter ◽  
Trindade Victoria ◽  
Terán Mariella ◽  
Gaudiano Javier ◽  
Ferrando Rodolfo ◽  
...  
Keyword(s):  
Neuroendocrine Tumor ◽  
Bone Pain ◽  
Tumor Therapy ◽  
Pain Palliation ◽  
Bone Pain Palliation
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