Most tall buildings are constructed in the prosperous center of large cities, where is inevitable to be surrounded by many interfering buildings. Wind interference effects among buildings should not be neglected. Therefore, it is necessary to investigate wind interference effects on such tall buildings. Based on the wind tunnel test of rigid model of a tall building, the wind pressure distribution on the building with interfering buildings around it has been researched, the contours of the mean and fluctuate wind pressure coefficients have also been presented. It has been found that shielding effect and channeling effect are significant in the wind interference effects on building. Wind pressure coefficients on side wall and leeward wall of a upstream building may be dramatically changed in case the wake boundary of the upstream building is interfered. The conclusions might be used as reference to structural design and plan.