A novel nipple–areola complex involvement predictive index for indicating nipple-sparing mastectomy in breast cancer patients

Breast Cancer ◽  
2019 ◽  
Vol 26 (6) ◽  
pp. 808-816 ◽  
Author(s):  
Hirohito Seki ◽  
Takashi Sakurai ◽  
Shodai Mizuno ◽  
Toshiki Tokuda ◽  
Takuji Kaburagi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Predictive Index ◽  
Nipple Areola Complex ◽  
Areola Complex ◽  
Nipple Sparing Mastectomy ◽  
Nipple Sparing

CHANGES IN THE NIPPLE-AREOLA COMPLEX IN PATIENTS WITH BREAST CANCER

2017 ◽  
Vol 63 (4) ◽  
pp. 593-597
Author(s):  
Aziz Zikiryakhodzhaev ◽  
Nadezhda Volchenko ◽  
Erik Saribekyan ◽  
Yelena Rasskazova
Keyword(s):  
Breast Cancer ◽  
Surgical Treatment ◽  
Cancer Patients ◽  
Molecular Subtypes ◽  
Breast Cancer Patients ◽  
Nipple Areola Complex ◽  
Histological Types ◽  
Areola Complex

The article presents data about the lesion of the nipple-areola complex in breast cancer. In 2015-2016 surgical treatment was performed in 101 breast cancer patients, different in size but with the mandatory removal of the nipple-areola complex. There are analyzed the dependence of the lesion of the nipple-areola complex from histological types of breast cancer, molecular subtypes, multicentricity, the location of tumor in the breast. The most significant criterion was the dependence of the lesion of the nipple-areola complex from the distance between tumor node and the nipple.

Nipple-sparing mastectomy: accuracy of sub-areolar frozen section for predicting occult NAC involvement in breast cancer patients

The Breast ◽  
2017 ◽  
Vol 32 ◽  
pp. S113
Author(s):  
M. D’Alonzo ◽  
A. Fenoglio ◽  
G. De Rosa ◽  
P. Campisi ◽  
P. Balocco ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Frozen Section ◽  
Breast Cancer Patients ◽  
Nipple Sparing Mastectomy ◽  
Nipple Sparing

Outcomes and feasibility of nipple-sparing mastectomy for node-positive breast cancer Patients

2017 ◽  
Vol 213 (4) ◽  
pp. 810-813 ◽  
Author(s):  
Brittany L. Murphy ◽  
Tanya L. Hoskin ◽  
Judy C. Boughey ◽  
Amy C. Degnim ◽  
James W. Jakub ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Node Positive ◽  
Nipple Sparing Mastectomy ◽  
Nipple Sparing ◽  
Positive Breast Cancer

Nipple-sparing mastectomy with primary implant reconstruction in breast cancer patients: Surgical and oncological outcome

2018 ◽  
Vol 92 ◽  
pp. S70
Author(s):  
Z. Radovanovic ◽  
M. Ranisavljevic ◽  
D. Radovanovic ◽  
F. Vicko ◽  
T. Ivkovic-Kapicl ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Oncological Outcome ◽  
Breast Cancer Patients ◽  
Primary Implant ◽  
Nipple Sparing Mastectomy ◽  
Nipple Sparing ◽  
Implant Reconstruction

scholarly journals Nipple sparing mastectomy in breast cancer patients and long-term survival outcomes: An analysis of the SEER database

PLoS ONE ◽  
2017 ◽  
Vol 12 (8) ◽  
pp. e0183448 ◽  
Author(s):  
Mingzhu Li ◽  
Kai Chen ◽  
Fengtao Liu ◽  
Fengxi Su ◽  
Shunrong Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Survival Outcomes ◽  
Seer Database ◽  
Breast Cancer Patients ◽  
Term Survival ◽  
Long Term Survival ◽  
Nipple Sparing Mastectomy ◽  
Nipple Sparing

Nipple–areola complex sparing mastectomy with periareolar pexy for breast cancer patients with moderately ptotic breasts

2012 ◽  
Vol 65 (3) ◽  
pp. 296-303 ◽  
Author(s):  
Alessandro Rivolin ◽  
Franziska Kubatzki ◽  
Francesco Marocco ◽  
Laura Martincich ◽  
Stefania Renditore ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Nipple Areola Complex ◽  
Areola Complex ◽  
Ptotic Breasts

Outcomes and feasibility of nipple-sparing mastectomy for node-positive breast cancer patients.

2015 ◽  
Vol 33 (28_suppl) ◽  
pp. 60-60 ◽  
Author(s):  
Brittany L. Murphy ◽  
Tanya L. Hoskin ◽  
Judy Caroline Boughey ◽  
Amy C. Degnim ◽  
James W. Jakub ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Oncologic Outcomes ◽  
Her2 Status ◽  
Breast Cancer Patients ◽  
Node Positive ◽  
Primary Surgery ◽  
Nipple Sparing Mastectomy ◽  
Nipple Sparing

60 Background: Indications for nipple-sparing mastectomy (NSM) with immediate reconstruction have expanded. For cancer patients, NSM is thought best-suited for early stage patients, with nodal involvement initially viewed as a relative contraindication. We undertook this study to evaluate the use and early outcomes of NSM in node-positive (LN+) breast cancer. Methods: We identified 240 cancers in 226 patients (14 bilateral) scheduled for NSM and operated on at our institution 1/2009-6/2014. Data on intraoperative conversion from NSM, recurrence and follow-up was abstracted from the medical record. Chi-square and long-rank tests were used for statistical analysis. P-values < 0.05 were considered significant. Results: Of 240 cancers, 182 were LN- and 58 were LN+. More LN+ patients had T2/T3 tumors (27/58, 47%) than LN- patients (31/182, 17%), p < 0.0001, but ER and HER2 status was similar. Of 58 LN+ cases, 19 (33%) were cN1 confirmed by positive LN cytology and 39 (67%) were cN0 but LN+ at operation. 10 patients LN+ at diagnosis received neoadjuvant therapy (NT) followed by operation (at which 6 were pLN+ and 4 rendered ypN0); 39 cN0 (4 NT, 35 primary surgery) and 9 cN1 primary surgery patients were pLN+ at operation with a median of 1 LN+. NSM was successful in 13/14 LN+ NT patients (93%) and 39/44 LN+ primary surgery patients (89%), p = 0.64. Six LN+ patients (10%) were converted to skin-sparing mastectomy (SSM) at initial operation based on frozen section pathology (n = 5) or at a second operation (n = 1) vs 13/182 LN- patients (7%), p = 0.44. Among cancer patients treated with NSM, 7 locoregional recurrences (5 in LN+, 2 in LN- patients) occurred at 25 mos median follow-up. 3-year locoregional disease-free estimates were 87% (95% CI 75-100%) for LN+ vs 99% (95% CI 97-100%) for LN- patients, p = 0.007. One nipple-areolar recurrence occurred, in a LN- patient. 3-year breast cancer-specific survival was 97% (95% CI 92-100%) in LN+ vs 99% (95% CI 98-100%) in LN- patients, p = 0.40. Conclusions: Conversion from planned NSM to SSM did not differ significantly between LN+ and LN- patients. Short-term oncologic outcomes were satisfactory. These data suggest that NSM may be appropriate for carefully selected LN+ breast cancer patients.

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