Neuroprotection by Remote Ischemic Conditioning in Rodent Models of Focal Ischemia: a Systematic Review and Meta-Analysis

Author(s):  
Allyson J. Ripley ◽  
Matthew S. Jeffers ◽  
Matthew W. McDonald ◽  
Joshua Montroy ◽  
Angela Dykes ◽  
...  
PLoS ONE ◽  
2012 ◽  
Vol 7 (7) ◽  
pp. e42179 ◽  
Author(s):  
Daniel Brevoord ◽  
Peter Kranke ◽  
Marijn Kuijpers ◽  
Nina Weber ◽  
Markus Hollmann ◽  
...  

Author(s):  
Rhaí André Arriel ◽  
Jéssica Ferreira Rodrigues ◽  
Hiago Leandro Rodrigues de Souza ◽  
Anderson Meireles ◽  
Luís Filipi Moutinho Leitão ◽  
...  

It has been demonstrated that brief cycles of ischemia followed by reperfusion (IR) applied before exercise can improve performance and, IR intervention, applied immediately after exercise (post-exercise ischemic conditioning – PEIC) exerts a potential ergogenic effect to accelerate recovery. Thus, the purpose of this systematic review with meta-analysis was to identify the effects of PEIC on exercise performance, recovery and the responses of associated physiological parameters, such as creatine kinase, perceived recovery and muscle soreness, over 24 h after its application. From 3281 studies, six involving 106 subjects fulfilled the inclusion criteria. Compared to sham (cuff administration with low pressure) and control interventions (no cuff administration), PEIC led to faster performance recovery (p=0.004; ES=-0.49) and lower increase in creatine kinase (p<0.001; ES=-0.71) and muscle soreness (p<0.001; ES=-0.89) over 24 h. The effectiveness of this intervention is more pronounced in subjects with low/moderate fitness level and at least a total time of 10 min of ischemia (e.g. 2 cycles of 5 min) is necessary to promote positive effects.


Stroke ◽  
2018 ◽  
Vol 49 (Suppl_1) ◽  
Author(s):  
Shimeng Liu ◽  
Rong Chen ◽  
Ran Meng ◽  
Qian Zhang ◽  
Qingfeng Ma ◽  
...  

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