A prospective study on delayed shoulder exercises in reducing seroma formation after modified radical mastectomy

Objective: Comparative outcome of one versus two drains insertion for in the term of seroma formation following modified radical mastectomy in breast carcinoma. Methodology: This Prospective Interventional trial was conducted at Department of General Surgery, Liaquat University Hospital Hyderabad from February 2018 to January 2019. Females with breast carcinoma admitted for modified radical mastectomy were included. Patients were divided into two groups. Groups I underwent one drain placement and group II underwent two drains placement. All patients were observed to measure and record the volume of the fluid. Patients were discharged from Hospital in stable condition and after removal of drains, and followed up weekly for one month. Data was recorded on self-made proforma and analyzed by using SPSS-20. Results: Total of 80 patients were selected, 38 in group A and 42 in group B. Mean age of patients of group A was 49.08 ± 9.89 years and group B was 51.40 ± 13.59 years. , Excised Mass weight was lesser in group A as compared to group B. Mean volume of drain discharge was significantly higher in Group B 323.43 ± 158.88 ml, while it was in group A 230.29± 200.98, findings were statistically significant 0.013. Seroma formation was statistically insignificant among both groups as 8(21.1%) in group A and 10(23.8%) in group B, p-value 0.768. Conclusion: One-drain and two-drain insertion are equally effective to reduce the seroma formation after modified radical mastectomy; however, one drain insertion leads to more patient compliance and comfort with probably less morbidity and cost.

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A Prospective Study on Post-Operative Complications Following Thyroid Surgery Conducted in a Tertiary Care Hospital in Tirupati

Journal of Evidence Based Medicine and Healthcare ◽

10.18410/jebmh/2021/530 ◽

2021 ◽

Vol 8 (31) ◽

pp. 2900-2905

Author(s):

Sadhu Nagamuneiah ◽

Gandikota Venkata Prakash ◽

Sabitha P ◽

Karthik Periyasamy ◽

Sanjay Raj Kumar Reddy Madduri ◽

...

Keyword(s):

Postoperative Complications ◽

Prospective Study ◽

Total Thyroidectomy ◽

General Hospital ◽

Thyroid Surgery ◽

Complication Rate ◽

Wound Complication ◽

Seroma Formation ◽

Operative Complications ◽

A Prospective Study

BACKGROUND Thyroidectomy is a surgical procedure which is commonly performed by surgeons worldwide, but the outcome and complication rates were mainly dependent on the surgeon’s skill and experience, indication and the extent of surgery and the number of thyroid surgeries performed at that particular centre. The aim of this study was to assess the frequency of the postoperative complications after thyroid surgery in Sri Venkateswara Ramnaraian Ruiya Government General Hospital, Tirupati. METHODS A prospective study conducted on 100 patients with thyroid swelling who attended the Sri Venkateshwara Ramnaraian Ruya Government General Hospital, Tirupati. Patient age, sex, rural/urban origin, history, diagnosis, type of surgery, laboratory investigation such as complete blood, serum calcium, thyroid function test, us culture and sensitivity test in wound infections and indirect laryngoscopy for all pre-operative patients and postoperative voice change patients. Outcomes recorded as a complication of thyroid surgery within one week. RESULTS Totally 100 patients were enrolled in the study. Thyroid enlargement was more common in females (F: M =5.6:1) presenting in 3rd and 4th decades mostly with the mean age and standard deviation were 42.92 years and 13.097 years respectively. Total thyroidectomy was the most common procedure performed (44 %) followed by hemithyroidectomy (31 %), subtotal thyroidectomies (29 %) and near total thyroidectomy (5 %). On histopathological examination most common finding was multinodular goiter (54 %) followed by nodular goiter (33 %) and malignancies (10 %). The overall postoperative complication rate was 47 %. The most common postoperative complications after thyroidectomies were seroma formation in wound complication (27 %), followed by hypocalcemia (11 %), recurrent laryngeal nerve (RLN) injury (3 %), and surgical site infection (2 %). Majority of these complications were found to be associated with total thyroidectomy, female population, and in patients with age more than 30 years. CONCLUSIONS Seroma formation in wound complication is the commonest post thyroidectomy complication. Female gender, old age, and extensive thyroid surgery were associated with increased complication rate. KEYWORDS Post-Operative Complications, Thyroid Surgery

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Comparison of electrocautery and plasmablade on ischemia and seroma formation after modified radical mastectomy for locally advanced breast cancer

Surgical Techniques Development ◽

10.4081/std.2017.7011 ◽

2017 ◽

Vol 7 (1) ◽

Cited By ~ 2

Author(s):

Husnu Alptekin ◽

Huseyin Yılmaz ◽

Bahadir Ozturk ◽

Ilhan Ece ◽

Mehmet Ertugrul Kafali ◽

...

Keyword(s):

Locally Advanced Breast Cancer ◽

Statistical Significance ◽

Locally Advanced ◽

Radical Mastectomy ◽

Seroma Formation ◽

Modified Radical Mastectomy ◽

Drainage Volume ◽

Drain Removal ◽

Postoperative Drainage ◽

The Mean

The aim of this study was to compare postoperative drainage volumes and IMA levels in patients who underwent modified radical mastectomy (MRM) with using PlasmaBlade (PB) or electrocautery (EC). A total of 36 patients who underwent MRM with PB or EC in our clinic between August 2012 to February 2013 were enrolled. Number of removed and positive lymph nodes, duration of drainage and total drainage volume was recorded. Seroma formation after drain removal and number of aspirations were also recorded. Serum ischemia modified albümine (IMA) levels were analysed before surgery, 1 hour and 24 hour after surgery. In total, 36 patients were treated with MRM in the study period. Of the 36 patients, 16 underwent MRM with PB, and 20 underwent MRM with EC. The patients demographics were similar in both groups. The mean drainage volume and seroma formation were significantly higher in the PB group when compared with EC group (P<0.05). Number of aspirations due to the seroma were also high in PB group. The total aspiration volume of seroma was not different in both groups. IMA levels 24 hours after surgery in the PB group was significantly higher than EC group. There was no statistical significance between the groups for IMA levels at 1st hour. PB is a monopolar energy device and is associated with increased levels of ischemia. This situation resulted with an increased volume of total axillary drainage and elevated risk of seroma formation.

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Efficacy of axillary exclusion on seroma formation after modified radical mastectomy

World Journal of Surgical Oncology ◽

10.1186/s12957-016-0801-0 ◽

2016 ◽

Vol 14 (1) ◽

Cited By ~ 4

Author(s):

Mohammed Faisal ◽

Sameh T Abu-Elela ◽

Waleed Mostafa ◽

Osama Antar

Keyword(s):

Radical Mastectomy ◽

Seroma Formation ◽

Modified Radical Mastectomy

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Influence of Fibrin Glue on Seroma Formation after Modified Radical Mastectomy: A Prospective Randomized Study

The Breast Journal ◽

10.1111/j.1524-4741.2009.00801.x ◽

2009 ◽

Vol 15 (6) ◽

pp. 671-672 ◽

Cited By ~ 7

Author(s):

Ayman El Nakeeb

Keyword(s):

Fibrin Glue ◽

Randomized Study ◽

Radical Mastectomy ◽

Seroma Formation ◽

Prospective Randomized Study ◽

Modified Radical Mastectomy

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Neoadjuvant Chemotherapy Does Not Decrease the Dose Requirement of Propofol for Inducing the Loss of Consciousness in Patients with Breast Cancer: A Prospective Study

Clinical Oncology and Research ◽

10.31487/j.cor.2020.01.05 ◽

2020 ◽

pp. 1-4

Author(s):

Juanyin Zhu ◽

Fei Xiao ◽

Guangfa Xia ◽

Juanyin Zhu ◽

Liu Lin ◽

...

Keyword(s):

Neoadjuvant Chemotherapy ◽

Physiological Function ◽

Radical Mastectomy ◽

Modify Radical Mastectomy ◽

Loss Of Consciousness ◽

Modified Radical Mastectomy ◽

Dose Requirement ◽

A Prospective Study ◽

To Receive ◽

Variable Dose

Background: Neoadjuvant chemotherapy can cause certain damage to patients’ physiological function. Therefore, we suspected that the sensitivity to propofol would also be altered by neoadjuvant chemotherapy. We aimed to compare the ED50 for inducing loss of consciousness (LOC) in patients with and without preoperative neoadjuvant chemotherapy. Methods: Sixty-two patients were randomized to receive neoadjuvant chemotherapy (group N) or not (group C) 10 to 15 days before elective modify radical mastectomy. The up-down method was used to determine the ED50 of propofol. Patients in each group received an initial dose of 4.0 μg/mL of propofol and a variable dose (increments or decrements) of 0.4 μg/mL of propofol based on the effective or ineffective response of the prior patient. The effective dose of propofol for induction of LOC in 50% patients was calculated and compared. Results: The EC50 and 95% confidence intervals (95%CI) of propofol in the two groups were 3.27 μg/mL (95%CI, 3.09～3.43 μg/mL) and 3.33μg/mL (95%CI, 3.19～3.47 μg/mL) for patients undergoing elective modified radical mastectomy with and without neoadjuvant chemotherapy respectively. Thus, there was no difference in the EC50s between the two groups, P = 0.55. Conclusions: Under the condition of this study, we found the EC50s of propofol for induction of LOC were 3.27 and 3.33 μg/mL for patients undergoing elective modified radical mastectomy in the presence or absence of neoadjuvant chemotherapy. We do not recommend reducing the dose of propofol for induction of LOC in patients with neoadjuvant chemotherapy.

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