Efficacy of Antenatal Ultrasound Examination in Diagnosis of Congenital Cardiac Anomalies in an Unselected Population: Retrospective Study from a Tertiary Centre

2021 ◽  
Author(s):  
N. D. Varunashree ◽  
Ravi Shankar ◽  
Preethi Navaneethan ◽  
Manish Kumar ◽  
Santosh Joseph Benjamin ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Ultrasound Examination ◽  
Antenatal Ultrasound ◽  
Cardiac Anomalies ◽  
Tertiary Centre ◽  
Congenital Cardiac Anomalies ◽  
Unselected Population

A population-based study of extra-cardiac anomalies in children with congenital cardiac malformations

2004 ◽  
Vol 14 (6) ◽  
pp. 600-607 ◽  
Author(s):  
Leif Eskedal ◽  
Petter Hagemo ◽  
Anne Eskild ◽  
Geir Aamodt ◽  
Karry Stephen Seiler ◽  
...  
Keyword(s):  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Population Based ◽  
Population Based Study ◽  
Cardiac Malformations ◽  
Cardiac Anomalies ◽  
Tertiary Centre ◽  
Congenital Cardiac Anomalies ◽  
Impact On Survival ◽  
Cardiac Lesions

We describe the prevalence of extra-cardiac anomalies in children with congenital cardiac malformations, and their impact on survival, compared to the outcome in children with the congenital cardiac lesions as the only recognised anomaly.Our population comprises the 3527 children born with congenital cardiac anomalies between 1990 and 1999, and registered at the largest tertiary centre for Paediatric Cardiology in Norway. Extra-cardiac anomalies were found in one-fifth of the population, with Down's syndrome accounting for nearly one-third. Survival improved for children born between 1995 and 1999 compared with those born in the period from 1990 to 1994 for all groups, except for children with additional extra-cardiac anomalies in the absence of Down's syndrome. The results were the same for children undergoing surgical treatment of their cardiac malformation. The survival in children with Down's syndrome improved in comparable fashion to those without extra-cardiac anomalies. Children with extra-cardiac anomalies in the absence of Down's syndrome represent a heterogeneous group, with varying patterns of survival. Survival did not improve in these latter patients during the period of our study.

scholarly journals Primary versus Staged Closure of Exomphalos Major: Cardiac Anomalies Do Not Affect Outcome

2017 ◽  
Vol 28 (03) ◽  
pp. 279-284 ◽  
Author(s):  
Clare Rees ◽  
Lucinda Tullie ◽  
Agostino Pierro ◽  
Edward Kiely ◽  
Joe Curry ◽  
...  
Keyword(s):  
Intensive Care ◽  
Length Of Stay ◽  
Primary Closure ◽  
Single Center ◽  
Fascial Defect ◽  
Pentalogy Of Cantrell ◽  
Cardiac Anomalies ◽  
Intensive Care Stay ◽  
Congenital Cardiac Anomalies ◽  
Liver Herniation

Aim The objective of the study is to describe management of exomphalos major and investigate the effect of congenital cardiac anomalies. Methods A single-center retrospective review (with audit approval) was performed of neonates with exomphalos major (fascial defect ≥ 5cm ± liver herniation) between 2004 and 2014.Demographic and operative data were collected and outcomes compared between infants who had primary or staged closure. Data, median (range), were analyzed appropriately. Results A total of 22 patients were included, 20 with liver herniation and 1 with pentalogy of Cantrell. Gestational age was 38 (30–40) weeks, birth weight 2.7 (1.4–4.6) kg, and 13 (60%) were male. Two were managed conservatively due to severe comorbidities, 5 underwent primary closure, and 15 had application of Prolene (Ethicon Inc) mesh silo and serial reduction. Five died, including two managed conservatively, none primarily of the exomphalos. Survivors were followed up for 38 months (2–71). Cardiac anomalies were present in 20 (91%) patients: 8 had minor and 12 major anomalies. Twelve (55%) patients had other anomalies. Primary closure was associated with shorter length of stay (13 vs. 85 days, p = 0.02), but infants had similar lengths of intensive care stay, duration of parenteral feeds, and time to full feeds. Infants with cardiac anomalies had shorter times to full closure (28 vs. 62 days, p = 0.03), but other outcomes were similar. Conclusion Infants whose defect can be closed primarily have a shorter length of stay, but other outcomes are similar. Infants with more significant abdominovisceral disproportion are managed with staged closure; the presence of major cardiac anomalies does not affect surgical outcome.

scholarly journals Age of puppies at referral to veterinary cardiology specialists for murmur investigation

2021 ◽  
Vol 63 (1) ◽  
Author(s):  
Lynn Bernadette Rovroy ◽  
Viktor Szatmári
Keyword(s):  
Medical Records ◽  
Digital Archive ◽  
Cardiac Anomaly ◽  
Time Interval ◽  
Health Examination ◽  
Cardiac Auscultation ◽  
Congenital Cardiac Anomaly ◽  
Cardiac Anomalies ◽  
Veterinary Practitioner ◽  
Congenital Cardiac Anomalies

Abstract Background Cardiac auscultation is an important screening test at the first health examination of puppies because most clinically relevant congenital cardiac anomalies cause a loud murmur from birth. This retrospective study aimed to investigate the age at which dogs with suspected congenital cardiac anomalies were referred to a veterinary cardiology specialist for murmur investigation. A secondary aim was to establish the time interval between the visit to the cardiologist and the first available murmur documentation. The digital archive of a veterinary teaching hospital was searched for dogs with congenital cardiac anomalies and puppies with innocent murmurs during a 5-year period. Dogs had to be referred because of a murmur, and they had to undergo physical examination and echocardiography by a veterinary cardiology specialist. The health certificate section of the pet passport, and the medical records from the referring veterinarian, were reviewed to identify the date when the murmur was first documented. Results Of the 271 included dogs, 94% had a congenital cardiac anomaly and 6% had an innocent murmur. The dogs’ median age was 190 days when they were examined by the cardiologist. Only 10% of the dogs were referred by the breeder’s veterinarian, while 90% of the dogs were referred by the new owner’s veterinarian. The median age of the first available murmur documentation by a first opinion veterinary practitioner was 95 days. Conclusions Only 10% of the puppies in the present study were referred to a veterinary cardiology specialist for murmur investigation before they were sold to a new owner. Referral prior to re-homing would have been feasible if the murmur had been detected and documented by the breeder’s veterinarian, if referral was offered by the breeder’s veterinarian and the referral was accepted by the breeder.

scholarly journals Rare Fetus-in-Fetu: Experience From a Large Tertiary Pediatric Referral Center

2021 ◽  
Vol 9 ◽  
Author(s):  
Mao Xiaowen ◽  
Cheng Lingxi ◽  
Lin Song ◽  
Pan Shengbao ◽  
Yang Xiaohong ◽  
...  
Keyword(s):  
Open Surgery ◽  
Clinical Characteristics ◽  
Ultrasound Examination ◽  
Single Case ◽  
Case Reports ◽  
Alpha Fetoprotein ◽  
Pathological Examination ◽  
Fetus In Fetu ◽  
Antenatal Ultrasound ◽  
Referral Center

Objective: Fetus-in-fetu (FIF) is an extremely rare disease, and most prior publications are single case reports. Here, we describe the clinical characteristics, imaging manifestations, and the treatment and related complications of FIF from a large tertiary pediatric referral center.Materials: After institutional review board approval, patients with a diagnosis of FIF between January 2010 and November 2019 were further selected and reexamined. We analyzed the general clinical characteristics, imaging manifestations, treatment, and prognosis of the patients.Results: A total of seven (four male and three female) patients with FIF were included in the study. All patients were diagnosed with FIF during the antenatal ultrasound examination along with an abnormal increase in alpha fetoprotein, and it was confirmed by subsequent pathological examination. The median gestation period when FIF was first diagnosed was 25 (range: 22–32) weeks. Ultrasound, computed tomography, and magnetic resonance imaging were the main pre-operative diagnostic techniques used. All patients underwent FIF resection within 1 month after birth: four patients had open surgery and three had laparoscopic surgeries (one case was converted to open surgery); only one patient developed ascites after surgery. All patients are growing up healthy and without tumor recurrence at the last follow-up. The level of alpha fetoprotein decreased to normal within 1 year (range 3-10 months) after surgery performed.Conclusion: As the size of the FIF increases, it can be found and diagnosed in antenatal ultrasound examination. Surgery is an important curative treatment for FIF and generally results in excellent long-term quality of life.

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