The Ameliorated Pharmacokinetics of VP-16 in Wistar Rats: A Possible Role of P-Glycoprotein Inhibition by Pharmaceutical Excipients

Naseem Akhtar; Abdul Ahad; Mohd Faiyaz Khan; Ayman Allaham; Sushama Talegaonkar

doi:10.1007/s13318-016-0332-7

The Ameliorated Pharmacokinetics of VP-16 in Wistar Rats: A Possible Role of P-Glycoprotein Inhibition by Pharmaceutical Excipients

European Journal of Drug Metabolism and Pharmacokinetics ◽

10.1007/s13318-016-0332-7 ◽

2016 ◽

Vol 42 (2) ◽

pp. 191-199 ◽

Cited By ~ 8

Author(s):

Naseem Akhtar ◽

Abdul Ahad ◽

Mohd Faiyaz Khan ◽

Ayman Allaham ◽

Sushama Talegaonkar

Keyword(s):

Wistar Rats ◽

Pharmaceutical Excipients ◽

P Glycoprotein ◽

Glycoprotein Inhibition

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Effects of Fluvastatin on the Pharmacokinetics of Repaglinide: Possible Role of CYP3A4 and P-glycoprotein Inhibition by Fluvastatin

Korean Journal of Physiology and Pharmacology ◽

10.4196/kjpp.2013.17.3.245 ◽

2013 ◽

Vol 17 (3) ◽

pp. 245 ◽

Cited By ~ 3

Author(s):

Chong-Ki Lee ◽

Jun-Shik Choi ◽

Joon Seok Bang

Keyword(s):

P Glycoprotein ◽

Glycoprotein Inhibition

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Effects of myricetin, an antioxidant, on the pharmacokinetics of losartan and its active metabolite, EXP-3174, in rats: possible role of cytochrome P450 3A4, cytochrome P450 2C9 and P-glycoprotein inhibition by myricetin

Journal of Pharmacy and Pharmacology ◽

10.1211/jpp.62.07.0012 ◽

2010 ◽

Vol 62 (7) ◽

pp. 908-914 ◽

Cited By ~ 26

Author(s):

Dong-Hyun Choi ◽

Cheng Li ◽

Jun-Shik Choi

Keyword(s):

Cytochrome P450 ◽

Active Metabolite ◽

Cytochrome P450 3A4 ◽

Cytochrome P450 2C9 ◽

P Glycoprotein ◽

Glycoprotein Inhibition

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Role of P-Glycoprotein Inhibition for Drug Interactions

Clinical Pharmacokinetics ◽

10.2165/00003088-200746120-00004 ◽

2007 ◽

Vol 46 (12) ◽

pp. 1039-1049 ◽

Cited By ~ 73

Author(s):

Sonja Eberl ◽

Bertold Renner ◽

Antje Neubert ◽

Mareike Reisig ◽

Iouri Bachmakov ◽

...

Keyword(s):

Drug Interactions ◽

P Glycoprotein ◽

Glycoprotein Inhibition

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Effects of lovastatin on the pharmacokinetics of verapamil and its active metabolite, norverapamil in rats: Possible role of P-glycoprotein inhibition by lovastatin

Archives of Pharmacal Research ◽

10.1007/s12272-009-2015-2 ◽

2009 ◽

Vol 32 (10) ◽

pp. 1447-1452 ◽

Cited By ~ 6

Author(s):

Soon-Pyo Hong ◽

Kyoung-Sig Chang ◽

Young-Youp Koh ◽

Dong-Hyun Choi ◽

Jun-Shik Choi

Keyword(s):

Active Metabolite ◽

P Glycoprotein ◽

Glycoprotein Inhibition

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Effects of baicalein on the pharmacokinetics of tamoxifen and its main metabolite, 4-hydroxytamoxifen, in rats: Possible role of cytochrome p450 3A4 and P-glycoprotein inhibition by baicalein

Archives of Pharmacal Research ◽

10.1007/s12272-011-1117-9 ◽

2011 ◽

Vol 34 (11) ◽

pp. 1965-1972 ◽

Cited By ~ 34

Author(s):

Cheng Li ◽

Minhee Kim ◽

HongSeok Choi ◽

JunShik Choi

Keyword(s):

Cytochrome P450 ◽

Cytochrome P450 3A4 ◽

Main Metabolite ◽

P Glycoprotein ◽

Glycoprotein Inhibition

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Effects of myricetin on the bioavailability of doxorubicin for oral drug delivery in Rats: Possible role of CYP3A4 and P-glycoprotein inhibition by myricetin

Archives of Pharmacal Research ◽

10.1007/s12272-011-0217-x ◽

2011 ◽

Vol 34 (2) ◽

pp. 309-315 ◽

Cited By ~ 18

Author(s):

Sang-Joon Choi ◽

Sang-Chul Shin ◽

Jun-Shik Choi

Keyword(s):

Drug Delivery ◽

Oral Drug Delivery ◽

Oral Drug ◽

P Glycoprotein ◽

Glycoprotein Inhibition

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Population pharmacokinetic modeling to establish the role of P-glycoprotein on ciprofloxacin distribution to lung and prostate following intravenous and intratracheal administration to Wistar rats

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2018.11.007 ◽

2019 ◽

Vol 127 ◽

pp. 319-329

Author(s):

Estevan Sonego Zimmermann ◽

Carolina de Miranda Silva ◽

Camila Neris ◽

Bruna Gaelzer da Silva Torres ◽

Stephan Schmidt ◽

...

Keyword(s):

Wistar Rats ◽

Pharmacokinetic Modeling ◽

Population Pharmacokinetic ◽

Intratracheal Administration ◽

Population Pharmacokinetic Modeling ◽

P Glycoprotein

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Boosting of HIV Protease Inhibitors by Ritonavir in the Intestine: The Relative Role of Cytochrome P450 and P-Glycoprotein Inhibition Based on Caco-2 Monolayers versus In Situ Intestinal Perfusion in Mice

Drug Metabolism and Disposition ◽

10.1124/dmd.112.044677 ◽

2012 ◽

Vol 40 (8) ◽

pp. 1473-1477 ◽

Cited By ~ 38

Author(s):

Nico Holmstock ◽

Pieter Annaert ◽

Patrick Augustijns

Keyword(s):

Cytochrome P450 ◽

Protease Inhibitors ◽

Hiv Protease ◽

Hiv Protease Inhibitors ◽

Relative Role ◽

P Glycoprotein ◽

In Situ Intestinal Perfusion ◽

Glycoprotein Inhibition

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Effects of Curcumin on the Pharmacokinetics of Loratadine in Rats: Possible Role of CYP3A4 and P-glycoprotein Inhibition by Curcumin

Biomolecules & Therapeutics ◽

10.4062/biomolther.2011.19.3.364 ◽

2011 ◽

Vol 19 (3) ◽

pp. 364-370 ◽

Cited By ~ 2

Author(s):

Cheng Li ◽

Byung-Chul Choi ◽

Dong-Ki Kim ◽

Jun-Shik Choi

Keyword(s):

P Glycoprotein ◽

Glycoprotein Inhibition

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Effects of efonidipine on the pharmacokinetics and pharmacodynamics of repaglinide: possible role of CYP3A4 and P-glycoprotein inhibition by efonidipine

Journal of Pharmacokinetics and Pharmacodynamics ◽

10.1007/s10928-011-9234-0 ◽

2012 ◽

Vol 39 (1) ◽

pp. 99-108 ◽

Cited By ~ 7

Author(s):

Cheng Li ◽

Dong-Hyun Choi ◽

Jun-Shik Choi

Keyword(s):

Pharmacokinetics And Pharmacodynamics ◽

P Glycoprotein ◽

Glycoprotein Inhibition

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