A new approach for skin tumor treatment: from delivery system characterization to in vivo evaluation

2011 ◽  
Vol 1 (1) ◽  
pp. 53-65 ◽  
Author(s):  
Denize Ainbinder ◽  
Elka Touitou
Keyword(s):  
Delivery System ◽  
Skin Tumor ◽  
Tumor Treatment ◽  
In Vivo Evaluation ◽  
New Approach ◽  
System Characterization

A Novel Intravaginal Delivery System for Itraconazole: In Vitro and In Vivo Evaluation

2009 ◽  
Vol 6 (2) ◽  
pp. 151-158 ◽  
Author(s):  
N. Dobaria ◽  
R. Mashru ◽  
A. Badhan ◽  
A. Thakkar
Keyword(s):  
Delivery System ◽  
In Vivo Evaluation ◽  
Intravaginal Delivery

Formulation, Characterization and In Vivo Evaluation of Self-Nanoemulsifying Drug Delivery System for Oral Delivery of Valsartan

2014 ◽  
Vol 10 (2) ◽  
pp. 263-270 ◽  
Author(s):  
Maulick Chopra ◽  
Usha Y. Nayak ◽  
Aravind Kumar Gurram ◽  
M. Sreenivasa Reddy ◽  
K.B. Koteshwara
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Oral Delivery ◽  
In Vivo Evaluation

Design of 99mTc radiolabeled gemcitabine polymeric nanoparticles as drug delivery system and in vivo evaluation

2021 ◽  
Vol 263 ◽  
pp. 124380
Author(s):  
Çiğdem İçhedef ◽  
Serap Teksöz ◽  
Oğuz Çetin ◽  
Burcu Aydın ◽  
İbrahim Sarıkavak ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Polymeric Nanoparticles ◽  
In Vivo Evaluation

scholarly journals Development of Triamcinolone Acetonide-Loaded Microemulsion as a Prospective Ophthalmic Delivery System for Treatment of Uveitis: In Vitro and In Vivo Evaluation

Pharmaceutics ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 444
Author(s):  
Alaa Mahran ◽  
Sayed Ismail ◽  
Ayat A. Allam
Keyword(s):  
Triamcinolone Acetonide ◽  
Delivery System ◽  
Histopathological Examination ◽  
Rabbit Model ◽  
Subconjunctival Injection ◽  
In Vivo Evaluation ◽  
Ternary Phase Diagrams ◽  
Ophthalmic Delivery

Treatment of uveitis (i.e., inflammation of the uvea) is challenging due to lack of convenient ophthalmic dosage forms. This work is aimed to determine the efficiency of triamcinolone acetonide (TA)-loaded microemulsion as an ophthalmic delivery system for the treatment of uveitis. Water titration method was used to construct different pseudo-ternary phase diagrams. Twelve microemulsion formulations were prepared using oleic acid, Cremophor EL, and propylene glycol. Among all tested formulations, Formulation F3, composed of oil: surfactant-co-surfactant (1:1): water (15:35:50% w/w, respectively), was found to be stable and showed acceptable pH, viscosity, conductivity, droplet size (211 ± 1.4 nm), and zeta potential (−25 ± 1.7 mV) and almost complete in vitro drug release within 24 h. The in vivo performance of the optimized formulation was evaluated in experimentally uveitis-induced rabbit model and compared with a commercial TA suspension (i.e., Kenacort®-A) either topically or by subconjunctival injection. Ocular inflammation was evaluated by clinical examination, white blood cell count, protein content measurement, and histopathological examination. The developed TA-loaded microemulsion showed superior therapeutic efficiency in the treatment of uveitis with high patient compliance compared to commercial suspension. Hence, it could be considered as a potential ocular treatment option in controlling of uveitis.

scholarly journals In vivo evaluation of a novel pH- and time-based multiunit colonic drug delivery system

2004 ◽  
Vol 20 (3) ◽  
pp. 347-353 ◽  
Author(s):  
C. Bott ◽  
M. W. Rudolph ◽  
A. R. J. Schneider ◽  
S. Schirrmacher ◽  
B. Skalsky ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
In Vivo Evaluation ◽  
Colonic Drug Delivery

In vivo evaluation of risperidone-SAIB in situ system as a sustained release delivery system in rats

2008 ◽  
Vol 68 (2) ◽  
pp. 422-429 ◽  
Author(s):  
Yaxin Lu ◽  
Xing Tang ◽  
Yue Cui ◽  
Yu Zhang ◽  
Feng Qin ◽  
...  
Keyword(s):  
Sustained Release ◽  
Delivery System ◽  
In Vivo Evaluation

scholarly journals In-vitro and in-vivo evaluation of a new amphotericin B emulsion-based delivery system

1996 ◽  
Vol 38 (3) ◽  
pp. 485-497 ◽  
Author(s):  
Eryvaldo Sόcrates Tabosa Do Egito ◽  
Martine Appel ◽  
Hatem Fessi ◽  
Gillian Barrett ◽  
Francis Puisieux ◽  
...  
Keyword(s):  
Amphotericin B ◽  
Delivery System ◽  
In Vivo Evaluation

In Vivo Evaluation of a Nasal Insulin Delivery System Based on Thiolated Chitosan

2006 ◽  
Vol 95 (11) ◽  
pp. 2463-2472 ◽  
Author(s):  
Alexander H. Krauland ◽  
Verena M. Leitner ◽  
Vjera Grabovac ◽  
Andreas Bernkop-Schnürch
Keyword(s):  
Delivery System ◽  
Insulin Delivery ◽  
In Vivo Evaluation ◽  
Thiolated Chitosan ◽  
Insulin Delivery System
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