scholarly journals 23rd Sanibel Conference on Mass Spectrometry: From Fragmentation Mechanisms to Sequencing: Tandem Mass Spectrometry Based Peptide and Protein Identification

2012 ◽  
Vol 23 (4) ◽  
pp. 575-576 ◽  
Author(s):  
Béla Paizs ◽  
Matthias Mann
Author(s):  
Haipeng Wang

Protein identification (sequencing) by tandem mass spectrometry is a fundamental technique for proteomics which studies structures and functions of proteins in large scale and acts as a complement to genomics. Analysis and interpretation of vast amounts of spectral data generated in proteomics experiments present unprecedented challenges and opportunities for data mining in areas such as data preprocessing, peptide-spectrum matching, results validation, peptide fragmentation pattern discovery and modeling, and post-translational modification (PTM) analysis. This article introduces the basic concepts and terms of protein identification and briefly reviews the state-of-the-art relevant data mining applications. It also outlines challenges and future potential hot spots in this field.


2020 ◽  
Vol 92 (17) ◽  
pp. 11895-11903
Author(s):  
Jifa Zhang ◽  
Erlu Feng ◽  
Wanru Li ◽  
Huaming Sheng ◽  
Jacob R. Milton ◽  
...  

2006 ◽  
Vol 6 (3) ◽  
pp. 527-536 ◽  
Author(s):  
Thomas S. Price ◽  
Margaret B. Lucitt ◽  
Weichen Wu ◽  
David J. Austin ◽  
Angel Pizarro ◽  
...  

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