scholarly journals The University of California San Diego performance-based skills assessment: a useful tool to detect mild everyday functioning difficulties in HIV-infected patients with very good immunological condition

2020 ◽  
Vol 26 (6) ◽  
pp. 899-907
Author(s):  
Valentina Delle Donne ◽  
Nicoletta Ciccarelli ◽  
Valentina Massaroni ◽  
Alberto Borghetti ◽  
Alex Dusina ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
San Diego ◽  
University Of California ◽  
Cognitive Domain ◽  
Skills Assessment ◽  
People Living With Hiv ◽  
Neurocognitive Performance ◽  
Everyday Functioning ◽  
The University ◽  
Immunological Condition

AbstractEveryday functioning (EF) impairment is frequent in people living with HIV (PLWH). Our aim was to better explore EF and its association with PLWH cognition, by administering both the IADL scale, the most common functional scale, and a new and ecologic multi-domain (communication and financial skills) tool to measure EF as the University of California San Diego (UCSD) Performance-Based Skills Assessment-Brief Version (UPSA-B). Eighty-five PLWH on cART with very good immunological condition and 23 age- and education-matched healthy controls (HC) were enrolled. PLWH underwent a standardized neuropsychological battery plus IADL, and cognitive impairment was defined according to Frascati criteria. Both groups underwent the UPSA-B. Only 6 subjects (7%) were affected by cognitive impairment (asymptomatic profile). While IADL score was at ceiling for all patients, the UPSA-B total score was significantly worse in PLWH when compared with HC [mean 82.1 (SD 9.3) vs 89.2 (SD 6.2); p < 0.001]. At communication subtest, PLWH group and HC were significantly different (p = 0.002), while no difference emerged at financial skills (p = 0.096). Higher score at UPSA-B was independently associated with better global cognitive performance (composite Z-score) (β 7.79; p < 0.001). Also considering each single cognitive domain, UPSA-B performance (both total and at subtests) confirmed the association with neurocognitive performance. In conclusion, UPSA-B seems to better discriminate EF impairment than IADL in PLWH, and it was associated with cognitive functions, also in the absence of symptomatic cognitive impairment. Thus, it appears a promising tool in the context of HIV infection to avoid misdiagnosis and to better detect also mild EF.

Developing clinical cut-off scores for the university of California San Diego performance-based skills assessment in patients with schizophrenia

2020 ◽  
Vol 47 ◽  
pp. 101844
Author(s):  
Sung-Young Park ◽  
Do-Un Jung ◽  
Sung-Jin Kim ◽  
Joo-Cheol Shim ◽  
Jung-Joon Moon ◽  
...  
Keyword(s):  
San Diego ◽  
University Of California ◽  
Skills Assessment ◽  
The University

scholarly journals The Korean Version of the University of California San Diego Performance-based Skills Assessment: Reliability and Validity

2017 ◽  
Vol 15 (3) ◽  
pp. 261-268 ◽  
Author(s):  
Sung-Jin Kim ◽  
Jung-Min Kim ◽  
Joo-Cheol Shim ◽  
Beom-Joo Seo ◽  
Sung-Soo Jung ◽  
...  
Keyword(s):  
San Diego ◽  
Reliability And Validity ◽  
University Of California ◽  
Skills Assessment ◽  
Korean Version ◽  
The University

University of California San Diego Performance-based Skills Assessment--Korean Version

2017 ◽  
Author(s):  
Sung-Jin Kim ◽  
Jung-Min Kim ◽  
Joo-Cheol Shim ◽  
Beom-Joo Seo ◽  
Sung-Soo Jung ◽  
...  
Keyword(s):  
San Diego ◽  
University Of California ◽  
Skills Assessment ◽  
Korean Version

Appraising Newness: Whiteness, Neoliberalism & the Building of the Archive for New Poetry

2017 ◽  
Vol 1 (2) ◽  
Author(s):  
Eunsong Kim
Keyword(s):  
San Diego ◽  
University Of California ◽  
Collection Development ◽  
Literary Scholarship ◽  
Avant Garde ◽  
Archival Practice ◽  
Small Press ◽  
The University

The Archive for New Poetry (ANP) at the University of California San Diego was founded with the specific intention of collecting alternative, small press publications and acquiring the manuscripts of contemporary new poets. The ANP’s stated collection development priority was to acquire alternative, non-mainstream, emerging, “experimental” poets as they were writing and alive, and to provide a space in which their papers could live, along with recordings of their poetry readings. In this article, I argue that through racialized understandings of innovation and new, whiteness positions the ANP’s collection development priority. I interrogate two main points in this article: 1) How does whiteness—though visible and open—remain unquestioned as an archival practice? and 2) How are white archives financed and managed? Utilizing the ANP’s financial proposals, internal administrative correspondences, and its manuscript appraisals and collections, I argue that the ANP’s collection development priority is racialized, and this prioritization is institutionally processed by literary scholarship that linked innovation to whiteness. Until very recently, US Experimental and “avant-garde” poetry has been indexed to whiteness. The indexing of whiteness to experimentation, or the “new” can be witnessed in the ANP’s collection development priorities, appraisals, and acquisitions. I argue that the structure of the manuscripts acquired by the ANP reflect literary scholarship that theorized new poetry as being written solely by white poets and conclude by examining the absences in the Archive for New Poetry.

HIV-Associated Neurocognitive Disorders

2019 ◽  
pp. 27-60
Author(s):  
Jennifer E.  Iudicello ◽  
Erin E. Morgan ◽  
Mariam A. Hussain ◽  
Caitlin Wei-Ming Watson ◽  
Robert K. Heaton
Keyword(s):  
Differential Diagnosis ◽  
Neurocognitive Impairment ◽  
Hiv Treatment ◽  
People Living With Hiv ◽  
Neurocognitive Disorder ◽  
Diagnostic Systems ◽  
Neurocognitive Performance ◽  
Everyday Functioning ◽  
Asymptomatic Neurocognitive Impairment ◽  
Age Related

Human immunodeficiency virus enters the central nervous system (CNS) early after systemic infection, and may cause neural injury and associated neurocognitive impairment through multiple direct and indirect mechanisms. An international conference of multidisciplinary neuroAIDS experts convened in 2005 to propose operationalized research criteria for HIV-related cognitive and everyday functioning impairments. The resulting classification system, known as the Frascati criteria, defined three types of HIV-associated neurocognitive disorder (HAND): asymptomatic neurocognitive impairment, mild neurocognitive disorder, and HIV-associated dementia (HAD). Consideration of comorbid conditions that can influence neurocognitive performance, such as developmental disabilities, non-HIV forms of CNS compromise (neurological and systemic), severe psychiatric conditions, and substance use disorders, is essential to differential diagnosis. Since the introduction of combination antiretroviral therapy (ART), rates of severe HAND (i.e., HAD) have greatly declined, although the milder forms of HAND remain quite prevalent, even in virally suppressed people living with HIV (PLWH). Beyond ART, clinical management of HAND includes behavioral interventions focused on neurocognitive and functional improvements. This chapter covers a range of HAND-related topics, such as the neuropathological mechanisms of HIV-related CNS injury, assessment and diagnostic systems for neurocognitive and everyday functioning impairment in HIV, treatment and protective factors, aging with HIV, HAND in international settings, and ongoing challenges and controversies in the field. Future needs for progress with HAND include advances in early detection of mild cognitive deficits and associated functional impairment in PLWH; biomarkers that may be sensitive to its underlying pathogenesis; and differential diagnosis of HAND versus age-related, non-HIV-associated disorders.

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