scholarly journals Coronavirus disease 2019 and peripheral blood eosinophil counts: a retrospective study

Infection ◽  
2021 ◽  
Author(s):  
Marjella Eijmael ◽  
Nicky Janssens ◽  
Saskia le Cessie ◽  
Yordi van Dooren ◽  
Ted Koster ◽  
...  
Keyword(s):  
Peripheral Blood ◽  
Medical Records ◽  
Clinical Severity ◽  
Blood Eosinophil ◽  
Chain Reaction ◽  
Peripheral Blood Eosinophil ◽  
Laboratory Results ◽  
The Mean ◽  
Polymerase Chain ◽  
Eosinophil Counts

Abstract Purpose Eosinopenia has been described in COVID-19. With this study, we aim to study the peripheral blood eosinophil counts in COVID-19 patients and to investigate whether there is an association between the peripheral blood eosinophil counts and disease severity of COVID-19. Methods We revised the electronical medical records of confirmed COVID-19 patients with polymerase chain reaction (PCR) assays in the Groene Hart Ziekenhuis, Gouda, The Netherlands. We divided patients in mild, moderate and severe groups based on clinical severity of COVID-19. Clinical severity was based on the therapy needed and the outcome of patients. We compared clinical characteristics, laboratory results and outcome between the three groups. Results Of the 230 patients included in this study, the mild, moderate and severe groups consisted of 16.5%, 45.7% and 37.8% of the included patients, respectively. The mean age was 68 years (IQR 57–78). 63% of patients were male. A significant decrease in the peripheral eosinophil counts was found corresponding to the increase of COVID-19 severity. In the mild, moderate and severe groups, the percentage of patients with eosinopenia was 73.7%, 86.7% and 94.3%, respectively (p value 0.002). Conclusion Eosinopenia is significantly more frequent present in patients with a severe COVID-19.

scholarly journals The role of peripheral blood eosinophil counts in COVID‐19 patients

Allergy ◽  
2020 ◽  
Author(s):  
Guogang Xie ◽  
Fengming Ding ◽  
Lei Han ◽  
Dongning Yin ◽  
Hongzhou Lu ◽  
...  
Keyword(s):  
Peripheral Blood ◽  
Blood Eosinophil ◽  
Peripheral Blood Eosinophil ◽  
Eosinophil Counts

Eosinophilia as a marker of resistance to Teladorsagia circumcincta in Scottish Blackface lambs

Parasitology ◽  
2002 ◽  
Vol 124 (5) ◽  
pp. 553-560 ◽  
Author(s):  
M. J. STEAR ◽  
N. G. HENDERSON ◽  
A. KERR ◽  
Q. A. MCKELLAR ◽  
S. MITCHELL ◽  
...  
Keyword(s):  
Peripheral Blood ◽  
Gastrointestinal Nematodes ◽  
Blood Eosinophil ◽  
Peripheral Blood Eosinophil ◽  
Teladorsagia Circumcincta ◽  
Peripheral Eosinophil ◽  
Faecal Egg Counts ◽  
Eosinophil Counts

Faecal egg counts and peripheral blood eosinophil counts were taken from Scottish Blackface lambs following natural, predominantly Teladorsagia circumcincta infection. Peripheral eosinophil concentrations were higher in animals with lower egg counts but only in lambs that were at least 3 months of age. The reduced egg counts were due to reduced fecundity of T. circumcincta; there was no association with the number of adult T. circumcincta. Associations with the number of parasites from other species of gastrointestinal nematodes appeared to be neutral or favourable. Estimated heritabilities for eosinophil concentrations in 4- and 5-month-old lambs were 0·48±0·16 and 0·43±0·17, respectively. Therefore, under defined circumstances, eosinophil concentrations may be a useful indicator of resistance to predominantly T. circumcincta infection.

scholarly journals The Relation Between Otolaryngology-Specific Symptoms and Computed Tomography Findings in Ambulatory Care COVID-19 Patients

2020 ◽  
pp. 014556132097550
Author(s):  
Hakan Avcı ◽  
Burak Karabulut
Keyword(s):  
Computed Tomography ◽  
Ambulatory Care ◽  
Medical Records ◽  
Negative Group ◽  
Chain Reaction ◽  
Positive Group ◽  
The Mean ◽  
Polymerase Chain ◽  
Specific Symptoms ◽  
Positive Groups

Objective: This study aimed to conduct a study to evaluate the relation between otolaryngology-specific symptoms and computed tomography findings in ambulatory care COVID-19 patients. Patient and Methods: The study was conducted with medical records of 987 (82%) patients with confirmed COVID-19 virus via real-time reverse transcription-polymerase chain reaction between March 11, 2020, and April 21, 2020. Patients were divided into 2 groups as computed tomography (CT)-negative and CT-positive groups considering the presence of the CT findings depicting COVID-19 disease. Results: The mean age was significantly higher in CT-positive group than CT-negative group (41.53 ± 12.82 vs 36.61 ± 11.81, P < .001). Cough and shortness of the breath were observed with a significantly higher rate in CT-positive group than that of CT-negative group (44% vs 29.9%, P = .001 and 18.4% vs 9.7%, P = .002, respectively). Conclusions: In conclusion, advanced age, cough, and shortness of breath could be related to CT scan positivity.

Decreased Peripheral Blood Eosinophil Counts in Severe Psoriatic Patients Treated with Low-Dose Cyclosporine A

Dermatology ◽  
1992 ◽  
Vol 185 (3) ◽  
pp. 202-204 ◽  
Author(s):  
J.L. Shupack ◽  
C. Kenny ◽  
L. Jondreau ◽  
I. Eckman ◽  
C. Gropper ◽  
...  
Keyword(s):  
Cyclosporine A ◽  
Peripheral Blood ◽  
Low Dose ◽  
Blood Eosinophil ◽  
Peripheral Blood Eosinophil ◽  
Eosinophil Counts

scholarly journals Prevalence and clinical implications of bronchiectasis in patients with overlapping asthma and chronic rhinosinusitis: a single-center prospective study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Haiyan Sheng ◽  
Xiujuan Yao ◽  
Xiangdong Wang ◽  
Yuhong Wang ◽  
Xiaofang Liu ◽  
...  
Keyword(s):  
Prospective Study ◽  
Chronic Rhinosinusitis ◽  
Peripheral Blood ◽  
Scoring System ◽  
Severe Disease ◽  
Airflow Obstruction ◽  
Blood Eosinophil ◽  
Severe Exacerbation ◽  
Peripheral Blood Eosinophil ◽  
Eosinophil Counts

Abstract Background As a typical “united airway” disease, asthma-chronic rhinosinusitis (CRS) overlap has recently drawn more attention. Bronchiectasis is a heterogeneous disease related to a variety of diseases. Whether bronchiectasis exists and correlates with asthma-CRS patients has not been fully elucidated. The purpose of the study was to explore the presence and characteristics of bronchiectasis in patients with overlapping asthma and CRS. Methods This report describes a prospective study with consecutive asthma-CRS patients. The diagnosis and severity of bronchiectasis were obtained by thorax high-resolution computed tomography (HRCT), the Smith radiology scale and the Bhalla scoring system. CRS severity was evaluated by paranasal sinus CT and the Lund-Mackay (LM) scoring system. The correlations between bronchiectasis and clinical data, fraction of exhaled nitric oxide, peripheral blood eosinophil counts and lung function were analyzed. Results Seventy-two (40.91%) of 176 asthma-CRS patients were diagnosed with bronchiectasis. Asthma-CRS patients with overlapping bronchiectasis had a higher incidence rate of nasal polyps (NPs) (P = 0.004), higher LM scores (P = 0.044), higher proportion of ≥ 1 severe exacerbation of asthma in the last 12 months (P = 0.003), lower postbronchodilator forced expiratory volume in one second (FEV1) % predicted (P = 0.006), and elevated peripheral blood eosinophil counts (P = 0.022). Smith and Bhalla scores were shown to correlate positively with NPs and negatively with FEV1% predicted and body mass index. Cutoff values of FEV1% predicted ≤ 71.40%, peripheral blood eosinophil counts > 0.60 × 109/L, presence of NPs, and ≥ 1 severe exacerbation of asthma in the last 12 months were shown to differentiate bronchiectasis in asthma-CRS patients. Conclusions Bronchiectasis commonly overlaps in asthma-CRS patients. The coexistence of bronchiectasis predicts a more severe disease subset in terms of asthma and CRS. We suggest that asthma-CRS patients with NPs, severe airflow obstruction, eosinophilic inflammation, and poor asthma control should receive HRCT for the early diagnosis of bronchiectasis.

scholarly journals Associations between peripheral blood eosinophil counts in patients with systemic sclerosis and disease severity

SpringerPlus ◽  
2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Katsutoshi Ando ◽  
Tamao Nakashita ◽  
Norihiro Kaneko ◽  
Kazuhisa Takahashi ◽  
Shinji Motojima
Keyword(s):  
Systemic Sclerosis ◽  
Disease Severity ◽  
Peripheral Blood ◽  
Blood Eosinophil ◽  
Peripheral Blood Eosinophil ◽  
Eosinophil Counts
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