Recent progress in hydrophobic ion-pairing and lipid-based drug delivery systems for enhanced oral delivery of biopharmaceuticals

2021 ◽  
Author(s):  
Gyubin Noh ◽  
Taekwang Keum ◽  
Santosh Bashyal ◽  
Jo-Eun Seo ◽  
Lamichhane Shrawani ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Oral Delivery ◽  
Drug Delivery Systems ◽  
Recent Progress ◽  
Ion Pairing ◽  
Delivery Systems ◽  
Hydrophobic Ion Pairing

Hydrophobic ion pairing: Key to highly payloaded self-emulsifying peptide drug delivery systems

2017 ◽  
Vol 520 (1-2) ◽  
pp. 267-274 ◽  
Author(s):  
Janine Griesser ◽  
Gergely Hetényi ◽  
Michael Moser ◽  
Frédéric Demarne ◽  
Vincent Jannin ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Ion Pairing ◽  
Delivery Systems ◽  
Peptide Drug ◽  
Hydrophobic Ion Pairing

Recent progress of macrophage vesicle-based drug delivery systems

2022 ◽  
Author(s):  
Wen-Jie Xu ◽  
Jia-Xin Cai ◽  
Yong-Jiang Li ◽  
Jun-Yong Wu ◽  
Daxiong Xiang
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Recent Progress ◽  
Delivery Systems

Nanoparticles with surface features of dendritic oligopeptides as potential oral drug delivery systems

2020 ◽  
Vol 8 (13) ◽  
pp. 2636-2649
Author(s):  
Yuli Bai ◽  
Rui Zhou ◽  
Lei Wu ◽  
Yaxian Zheng ◽  
Xi Liu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Specific Surface ◽  
Oral Delivery ◽  
Drug Delivery Systems ◽  
Oral Drug Delivery ◽  
Delivery Systems ◽  
Oral Drug ◽  
Protein Drugs ◽  
Surface Features ◽  
Oral Drug Delivery Systems

Endowing the NPs with specific surface features of dendritic oligopeptides holds great potential for the oral delivery of peptide/protein drugs.

Paliperidone-Loaded Self-Emulsifying Drug Delivery Systems (SEDDS) for Improved Oral Delivery

2012 ◽  
Vol 33 (4) ◽  
pp. 506-515 ◽  
Author(s):  
Swetha Kanuganti ◽  
Raju Jukanti ◽  
Prabhakar R. Veerareddy ◽  
Suresh Bandari
Keyword(s):  
Drug Delivery ◽  
Oral Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems

A prodrug strategy for the oral delivery of a poorly soluble HCV NS5B thumb pocket 1 polymerase inhibitor using self-emulsifying drug delivery systems (SEDDS)

2015 ◽  
Vol 25 (2) ◽  
pp. 210-215 ◽  
Author(s):  
Pierre L. Beaulieu ◽  
Josie De Marte ◽  
Michel Garneau ◽  
Laibin Luo ◽  
Timothy Stammers ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Oral Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Poorly Soluble ◽  
Polymerase Inhibitor ◽  
Hcv Ns5b

scholarly journals Inflammatory Bowel Disease: The Emergence of New Trends in Lifestyle and Nanomedicine as the Modern Tool for Pharmacotherapy

Nanomaterials ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 2460
Author(s):  
Eden Mariam Jacob ◽  
Ankita Borah ◽  
Sindhu C Pillai ◽  
D. Sakthi Kumar
Keyword(s):  
Drug Delivery ◽  
Inflammatory Bowel Disease ◽  
Immune System ◽  
Bowel Disease ◽  
Oral Delivery ◽  
Drug Delivery Systems ◽  
Genetic Defect ◽  
Delivery Systems ◽  
Conventional Drug ◽  
Inflammatory Bowel

The human intestine, which harbors trillions of symbiotic microorganisms, may enter into dysbiosis when exposed to a genetic defect or environmental stress. The naissance of chronic inflammation due to the battle of the immune system with the trespassing gut bacteria leads to the rise of inflammatory bowel disease (IBD). Though the genes behind the scenes and their link to the disease are still unclear, the onset of IBD occurs in young adults and has expanded from the Western world into the newly industrialized countries. Conventional drug deliveries depend on a daily heavy dosage of immune suppressants or anti-inflammatory drugs targeted for the treatment of two types of IBD, ulcerative colitis (UC) and Crohn’s disease (CD), which are often associated with systemic side effects and adverse toxicities. Advances in oral delivery through nanotechnology seek remedies to overcome the drawbacks of these conventional drug delivery systems through improved drug encapsulation and targeted delivery. In this review, we discuss the association of genetic factors, the immune system, the gut microbiome, and environmental factors like diet in the pathogenesis of IBD. We also review the various physiological concerns required for oral delivery to the gastrointestinal tract (GIT) and new strategies in nanotechnology-derived, colon-targeting drug delivery systems.

scholarly journals Recent progress on nanoparticle-based drug delivery systems for cancer therapy

2017 ◽  
Vol 14 (3) ◽  
pp. 228 ◽  
Author(s):  
Yanru Xin ◽  
Mingming Yin ◽  
Liyuan Zhao ◽  
Fanling Meng ◽  
Liang Luo
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery Systems ◽  
Recent Progress ◽  
Delivery Systems
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