Efficacy and Safety of Intravenously Administered Tramadol in Patients with Moderate to Severe Pain Following Bunionectomy: A Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Study

Neil K. Singla; Richard Pollak; Ira Gottlieb; David Leiman; Harold Minkowitz; John Zimmerman; Mark Harnett; Michael Ryan; Lucy Lu; Scott Reines

doi:10.1007/s40122-020-00184-2

Efficacy and Safety of Intravenously Administered Tramadol in Patients with Moderate to Severe Pain Following Bunionectomy: A Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Study

Pain and Therapy ◽

10.1007/s40122-020-00184-2 ◽

2020 ◽

Vol 9 (2) ◽

pp. 545-562

Author(s):

Neil K. Singla ◽

Richard Pollak ◽

Ira Gottlieb ◽

David Leiman ◽

Harold Minkowitz ◽

...

Keyword(s):

Severe Pain ◽

Dose Finding ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Finding Study ◽

Dose Finding Study

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A 9-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Dose-Finding Study to Evaluate the Efficacy and Safety of Modafinil as Treatment for Adults With ADHD

Journal of Attention Disorders ◽

10.1177/1087054712441969 ◽

2012 ◽

Vol 18 (2) ◽

pp. 133-144 ◽

Cited By ~ 21

Author(s):

Valerie K. Arnold ◽

David Feifel ◽

Craig Q. Earl ◽

Ronghua Yang ◽

Lenard A. Adler

Keyword(s):

Dose Finding ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Parallel Group ◽

Finding Study ◽

Dose Finding Study

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Efficacy and Safety of the Selective β3-Adrenoceptor Agonist Mirabegron in Japanese Patients with Overactive Bladder: A Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Study

LUTS Lower Urinary Tract Symptoms ◽

10.1111/luts.12053 ◽

2014 ◽

Vol 7 (2) ◽

pp. 84-92 ◽

Cited By ~ 15

Author(s):

Osamu YAMAGUCHI ◽

Eiji MARUI ◽

Yasuhiko IGAWA ◽

Masayuki TAKEDA ◽

Osamu NISHIZAWA ◽

...

Keyword(s):

Overactive Bladder ◽

Japanese Patients ◽

Dose Finding ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Adrenoceptor Agonist ◽

Finding Study ◽

Dose Finding Study

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Efficacy and safety of a crystalline lactulose preparation (SK-1202) in Japanese patients with chronic constipation: a randomized, double-blind, placebo-controlled, dose-finding study

Journal of Gastroenterology ◽

10.1007/s00535-018-01545-7 ◽

2019 ◽

Vol 54 (6) ◽

pp. 530-540 ◽

Cited By ~ 4

Author(s):

Kunio Kasugai ◽

Hisakazu Iwai ◽

Noboru Kuboyama ◽

Aya Yoshikawa ◽

Shin Fukudo

Keyword(s):

Chronic Constipation ◽

Japanese Patients ◽

Dose Finding ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Finding Study ◽

Dose Finding Study

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The efficacy and safety of S-flurbiprofen plaster in the treatment of knee osteoarthritis: a phase II, randomized, double-blind, placebo-controlled, dose-finding study

Journal of Pain Research ◽

10.2147/jpr.s131779 ◽

2017 ◽

Vol Volume 10 ◽

pp. 867-880 ◽

Cited By ~ 1

Author(s):

Ikuko Yataba ◽

Noboru Otsuka ◽

Isao Matsushita ◽

Hideo Matsumoto ◽

Yuichi Hoshino

Keyword(s):

Knee Osteoarthritis ◽

Phase Ii ◽

Dose Finding ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Finding Study ◽

Dose Finding Study

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Efficacy and safety of d-sotalol, a pure class III antiarrhythmic compound, in patients with symptomatic complex ventricular ectopy: Results of a multicenter, randomized, double-blind, placebo-controlled dose-finding study

ACC Current Journal Review ◽

10.1016/1062-1458(96)85195-6 ◽

1996 ◽

Vol 5 (1) ◽

pp. 57

Keyword(s):

Dose Finding ◽

Ventricular Ectopy ◽

Efficacy And Safety ◽

Class Iii ◽

Double Blind ◽

Double Blind Placebo ◽

Finding Study ◽

Dose Finding Study

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Efficacy and Safety of a Novel Botulinum Toxin A for Masseter Reduction: A Randomized, Double-Blind, Placebo-Controlled, Optimal Dose-Finding Study

Dermatologic Surgery ◽

10.1097/dss.0000000000002475 ◽

2021 ◽

Vol 47 (1) ◽

pp. e5-e9

Author(s):

Ji Yeon Hong ◽

Guk Jin Jeong ◽

Tae-Rin Kwon ◽

Jong Hwan Kim ◽

Kapsok Li ◽

...

Keyword(s):

Botulinum Toxin ◽

Botulinum Toxin A ◽

Optimal Dose ◽

Dose Finding ◽

Efficacy And Safety ◽

Toxin A ◽

Double Blind ◽

Double Blind Placebo ◽

Finding Study ◽

Dose Finding Study

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Efficacy and safety of bifeprunox in patients with an acute exacerbation of schizophrenia: results from a randomized, double-blind, placebo-controlled, multicenter, dose-finding study

Psychopharmacology ◽

10.1007/s00213-008-1207-7 ◽

2008 ◽

Vol 200 (3) ◽

pp. 317-331 ◽

Cited By ~ 44

Author(s):

Daniel E. Casey ◽

Earl E. Sands ◽

Jens Heisterberg ◽

Hwa-Ming Yang

Keyword(s):

Acute Exacerbation ◽

Dose Finding ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Finding Study ◽

Dose Finding Study

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Deramciclane in the treatment of patients with generalised anxiety disorder: A randomised, double-blind, placebo-controlled, dose-finding study

European Neuropsychopharmacology ◽

10.1016/s0924-977x(01)80407-7 ◽

2001 ◽

Vol 11 ◽

pp. S301-S302 ◽

Cited By ~ 3

Author(s):

H. Naukkarinen

Keyword(s):

Anxiety Disorder ◽

Dose Finding ◽

Generalised Anxiety Disorder ◽

Double Blind ◽

Double Blind Placebo ◽

Finding Study ◽

Dose Finding Study

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Low-Dose Interleukin 2 in Children with Recently Diagnosed Type 1 Diabetes: A Phase 1/2 Randomised, Double-Blind, Placebo-Controlled Dose Finding Study

SSRN Electronic Journal ◽

10.2139/ssrn.3384899 ◽

2019 ◽

Author(s):

Randa Salet ◽

Michelle Rosenzwajg ◽

Roberta Lorenzon ◽

Alexandra Roux ◽

Jean Claude Carel ◽

...

Keyword(s):

Type 1 Diabetes ◽

Low Dose ◽

Phase 1 ◽

Interleukin 2 ◽

Dose Finding ◽

Double Blind ◽

Double Blind Placebo ◽

Finding Study ◽

Dose Finding Study

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The effect on bone mass and bone markers of different doses of ibandronate — A new bisphosphonate for prevention and treatment of postmenopausal osteoporosis. A 1-year, randomized, double-blind, placebo-controlled dose-finding study

Osteoporosis International ◽

10.1007/bf02500731 ◽

1996 ◽

Vol 6 (S1) ◽

pp. 301-301 ◽

Cited By ~ 1

Author(s):

P. Ravn ◽

B. Clemmesen ◽

B. J. Riis ◽

C. Christiansen

Keyword(s):

Bone Mass ◽

Postmenopausal Osteoporosis ◽

Bone Markers ◽

Dose Finding ◽

Double Blind ◽

Double Blind Placebo ◽

Prevention And Treatment ◽

Finding Study ◽

Dose Finding Study ◽

Different Doses

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