A Novel Once-Daily Fixed-Dose Combination of Memantine Extended Release and Donepezil for the Treatment of Moderate to Severe Alzheimer’s Disease: Two Phase I Studies in Healthy Volunteers

Ramesh Boinpally; Laishun Chen; Stephen R. Zukin; Natalie McClure; Robert K. Hofbauer; Antonia Periclou

doi:10.1007/s40261-015-0296-4

A Novel Once-Daily Fixed-Dose Combination of Memantine Extended Release and Donepezil for the Treatment of Moderate to Severe Alzheimer’s Disease: Two Phase I Studies in Healthy Volunteers

Clinical Drug Investigation ◽

10.1007/s40261-015-0296-4 ◽

2015 ◽

Vol 35 (7) ◽

pp. 427-435 ◽

Cited By ~ 9

Author(s):

Ramesh Boinpally ◽

Laishun Chen ◽

Stephen R. Zukin ◽

Natalie McClure ◽

Robert K. Hofbauer ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Phase I ◽

Healthy Volunteers ◽

Extended Release ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Two Phase ◽

Once Daily ◽

Phase I Studies ◽

Dose Combination

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P3-391: PHARMACOKINETICS OF MEMANTINE AND DONEPEZIL AFTER A SINGLE DOSE OF A ONCE-DAILY FIXED-DOSE COMBINATION CAPSULE OF MEMANTINE EXTENDED RELEASE AND DONEPEZIL IN TWO PHASE I TRIALS

Alzheimer s & Dementia ◽

10.1016/j.jalz.2014.05.1485 ◽

2014 ◽

Vol 10 ◽

pp. P772-P773

Author(s):

Ramesh Boinpally ◽

Robert Hofbauer ◽

Laishun Chen ◽

Stephen Zukin ◽

Antonia Periclou

Keyword(s):

Single Dose ◽

Phase I ◽

Extended Release ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Phase I Trials ◽

Two Phase ◽

Once Daily ◽

Dose Combination

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Skin Irritation and Sensitization Potential of Fixed-Dose Combination of Diclofenac 1% and Menthol 3% Topical Gel: Results of Two Phase I Patch Studies

Drug Research ◽

10.1055/s-0042-118861 ◽

2016 ◽

Vol 67 (02) ◽

pp. 119-126

Author(s):

Dongzhou Liu ◽

Agron Collaku ◽

Jonathan Dosik

Keyword(s):

Phase I ◽

Skin Irritation ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Two Phase ◽

Topical Gel ◽

Dose Combination

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A randomized Phase I bioequivalence clinical trial of a pediatric fixed-dose combination antiretroviral reconstitutable suspension in healthy adult volunteers

Antiviral Therapy ◽

10.3851/imp2310 ◽

2012 ◽

Vol 18 (2) ◽

pp. 205-212 ◽

Cited By ~ 6

Author(s):

Fredrick Esseku ◽

Anjali Joshi ◽

Yemisi Oyegbile ◽

Grace Edowhorhu ◽

Daniel Gbadero ◽

...

Keyword(s):

Clinical Trial ◽

Phase I ◽

Healthy Adult ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Dose Combination ◽

Adult Volunteers

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Different daily glycemic profiles after switching from once-daily alogliptin plus twice-daily metformin to their once-daily fixed-dose combination in Japanese type 2 diabetic patients

Endocrine Journal ◽

10.1507/endocrj.ej18-0313 ◽

2019 ◽

Vol 66 (1) ◽

pp. 11-17

Author(s):

Mitsuyoshi Takahara ◽

Toshihiko Shiraiwa ◽

Naoto Katakami ◽

Yoshifumi Maeno ◽

Kaoru Yamamoto ◽

...

Keyword(s):

Fixed Dose Combination ◽

Fixed Dose ◽

Diabetic Patients ◽

Type 2 Diabetic Patients ◽

Once Daily ◽

Dose Combination ◽

Type 2 Diabetic

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Pharmacokinetic Bioequivalence Studies of a Fixed-Dose Combination of Tamsulosin and Dutasteride in Healthy Volunteers

Clinical Drug Investigation ◽

10.1007/s40261-014-0179-0 ◽

2014 ◽

Vol 34 (5) ◽

pp. 335-349 ◽

Cited By ~ 4

Author(s):

Michael J. Fossler ◽

David A. Collins ◽

Meg M. Thompson ◽

Antonio Nino ◽

Joseph J. Bianco ◽

...

Keyword(s):

Healthy Volunteers ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Dose Combination

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P1156 DACLATASVIR, ASUNAPREVIR, AND BMS-791325 IN A FIXED-DOSE COMBINATION: A PHASE 1 BIOAVAILABILITY STUDY IN HEALTHY VOLUNTEERS

Journal of Hepatology ◽

10.1016/s0168-8278(14)61316-7 ◽

2014 ◽

Vol 60 (1) ◽

pp. S468-S469 ◽

Cited By ~ 1

Author(s):

R. Adamczyk ◽

K. Sims ◽

I. Chang ◽

D. Filoramo ◽

J. Pursley ◽

...

Keyword(s):

Healthy Volunteers ◽

Phase 1 ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Bioavailability Study ◽

Dose Combination

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Spray Drying as a Fast and Simple Technique for the Preparation of Extended Release Dipyridamole (DYP) Microparticles in a Fixed Dose Combination (FDC) Product with Aspirin

Drug Research ◽

10.1055/s-0033-1361119 ◽

2013 ◽

Vol 64 (02) ◽

pp. e1-e1

Author(s):

H. Hamishehkar ◽

H. Valizadeh ◽

P. Alasty ◽

F. Monajjemzadeh

Keyword(s):

Spray Drying ◽

Extended Release ◽

Simple Technique ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Dose Combination

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882 PHASE I EVALUATION OF THVD-201, A FIXED-DOSE COMBINATION OF TOLTERODINE AND PILOCARPINE, TO ELIMINATE THE DRY MOUTH SIDE EFFECT OF ANTI-MUSCARINIC THERAPY FOR OVERACTIVE BLADDER

European Urology Supplements ◽

10.1016/s1569-9056(11)60866-x ◽

2011 ◽

Vol 10 (2) ◽

pp. 277 ◽

Cited By ~ 1

Author(s):

M. Paborji ◽

R. Flugel

Keyword(s):

Overactive Bladder ◽

Phase I ◽

Side Effect ◽

Fixed Dose Combination ◽

Dry Mouth ◽

Fixed Dose ◽

Dose Combination

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Bioequivalence, Food Effect, and Steady‐State Assessment of Dapagliflozin/Metformin Extended‐release Fixed‐dose Combination Tablets Relative to Single‐component Dapagliflozin and Metformin Extended‐release Tablets in Healthy Subjects

Clinical Therapeutics ◽

10.1016/j.clinthera.2015.05.004 ◽

2015 ◽

Vol 37 (7) ◽

pp. 1517-1528 ◽

Cited By ~ 9

Author(s):

Ming Chang ◽

Xiaoni Liu ◽

Dapeng Cui ◽

Dan Liang ◽

Frank LaCreta ◽

...

Keyword(s):

Steady State ◽

Healthy Subjects ◽

Extended Release ◽

Food Effect ◽

State Assessment ◽

Single Component ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Dose Combination

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Bioequivalence Study of a Fixed Dose Combination of Nitazoxanide and Ofloxacin in Indian Healthy Volunteers

Arzneimittelforschung ◽

10.1055/s-0031-1296667 ◽

2011 ◽

Vol 57 (10) ◽

pp. 679-683

Author(s):

Sangita Agarwal ◽

W. Solomon ◽

K. Gowda ◽

P. Selvan ◽

Debotri Ghosh ◽

...

Keyword(s):

Healthy Volunteers ◽

Bioequivalence Study ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Dose Combination

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