scholarly journals A retrospective chart review study of symptom onset, diagnosis, comorbidities, and treatment in patients with binge eating disorder in Canadian clinical practice

Author(s):  
Simerpal K. Gill ◽  
Allan S. Kaplan

Abstract Purpose In the Canadian healthcare setting, there is limited understanding of the pathways to diagnosis and treatment for patients with binge eating disorder (BED). Methods This retrospective chart review examined the clinical characteristics, diagnostic pathways, and treatment history of adult patients diagnosed with BED. Results Overall, 202 charts from 57 healthcare providers (HCPs) were reviewed. Most patients were women (69%) and white (78%). Mean ± SD patient age was 37 ± 12.1 years. Comorbidities identified in > 20% of patients included obesity (50%), anxiety (49%), depression and/or major depressive disorder (46%), and dyslipidemia (26%). Discussions regarding a diagnosis of BED were typically initiated more often by HCPs than patients. Most patients (64%) received a diagnosis of BED ≥ 3 years after symptom onset. A numerically greater percentage of patients received (past or current) nonpharmacotherapy than pharmacotherapy (84% vs. 67%). The mean ± SD number of binge eating episodes/week numerically decreased from pretreatment to follow-up with lisdexamfetamine (5.4 ± 2.8 vs. 1.7 ± 1.2), off-label pharmacotherapy (4.7 ± 3.9 vs. 2.0 ± 1.13), and nonpharmacotherapy (6.3 ± 4.8 vs. 3.5 ±  6.0) Across pharmacotherapies and nonpharmacotherapies, most patients reported improvement in symptoms of BED (84–97%) and in overall well-being (80–96%). Conclusions These findings highlight the importance of timely diagnosis and treatment of BED. Although HCPs are initiating discussions about BED, earlier identification of BED symptoms is required. Furthermore, these data indicate that pharmacologic and nonpharmacologic treatment for BED is associated with decreased binge eating and improvements in overall well-being. Level of evidence IV, chart review.

2011 ◽  
Vol 39 (4) ◽  
pp. 443-456 ◽  
Author(s):  
Lisa Graham ◽  
Mark Walton

Background: Many patients who experience bulimia nervosa (BN) and binge eating disorder (BED) find it hard to access evidence-based treatments. Rates of failure to enter outpatient services following initial assessment are high, as are dropout rates from specialist outpatient eating disorders services. Aims: To offer CD-Rom CBT, a cognitive-behavioural multi-media supported self-help treatment, in a locality-based outpatient NHS Eating Disorders Service to patients who have binge eating disorder and bulimia nervosa. Method: Patients referred to a catchment-based NHS outpatient eating disorders service who were assessed and had an eating disorder with a binge-eating component were offered CD-Rom based CBT (Overcoming Bulimia) whilst on the waiting list for individual CBT. Results: Forty patients completed the 8 sessions and attended the evaluation appointment (13 had BN, 27 had BED). For both groups, there were significant improvements in well-being and functioning, as well as significant reductions in problems and risk. There was also a significant reduction on the “Bulimic Subscale” of the EDI. These results were comparable with the original study findings (Schmidt, Treasure and Williams, 2001). Dropouts from the CD-Rom reflected rates common to other EDS treatments suggesting that CD-Rom did not directly impact upon service dropout rates. Conclusions: Computer assisted CBT for Eating Disorders offers a promising, feasible and acceptable first step for patients who have bulimia nervosa or binge eating disorder and access treatment from specialist eating disorders services.


2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Federico Amianto ◽  
Luisa Ottone ◽  
Giovanni Abbate Daga ◽  
Secondo Fassino

2019 ◽  
Vol 39 (8) ◽  
pp. NP322-NP330 ◽  
Author(s):  
Nneamaka Agochukwu-Nwubah ◽  
Ashley Boustany ◽  
Margaret Wetzel ◽  
Jacob Maus ◽  
Brian Rinker

Abstract Background Direct comparison studies of outcomes and aesthetic satisfaction of anatomic implants compared to other implants are scarce in the literature. Objectives The objective of this study was to compare outcomes and aesthetic satisfaction of patients who underwent breast reconstruction with anatomic implants vs other implants (smooth round silicone). Methods A retrospective chart review was performed of patients who underwent implant-based breast reconstruction over 3 years. Outcomes including complications, number of surgeries, need for revisions, and aesthetic satisfaction of patients were tracked and compared. Results A total of 156 patients met inclusion criteria for this study. A total of 123 underwent reconstruction with a round implant, and 33 underwent reconstruction with an anatomic implant. Of the 156 patients, 38 underwent a 1-stage direct-to-implant reconstruction and the remainder underwent a 2-stage implant reconstruction. The round and anatomic implant groups did not differ with regards to number of surgeries, revisions, utilization of contralateral symmetry procedures, implant-related reoperations, complications, implant loss, infection, capsular contracture, and seroma. The Breast Q survey had a response rate of 27%. On all parameters, the round and anatomic implant groups did not significantly differ. Conclusions There were no significant differences among round and shaped implants in regards to complications, revision surgeries, and overall outcomes. Furthermore, patients showed no differences regarding satisfaction and well-being when surveyed on the Breast Q survey. The decision of implant choice in breast reconstruction should be based on surgeon comfort and the patient’s needs/body type. Level of Evidence: 4


2021 ◽  
Author(s):  
Alessio Maria Monteleone ◽  
Orna Tzischinsky ◽  
Giammarco Cascino ◽  
Sigal Alon ◽  
Francesca Pellegrino ◽  
...  

Abstract Purpose. Childhood maltreatment (CM) experiences are associated with heightened risk of Eating Disorders (EDs). The psychopathological pathways promoting this association in people with Bulimia Nervosa (BN) and in those with Binge Eating Disorder (BED) are under-investigated. Methods. One-hundred-eighty-one people with BN and 144 with BED filled in the Eating Disorder Inventory-2, to measure ED psychopathology, and the Childhood Trauma Questionnaire, to assess their early traumatic experiences. Network analysis was conducted in order to investigate the interplay between those variables. The shortest pathways function was employed to investigate the shortest out of all routes conveying the association between CM and ED core symptoms. Results. In both people with BN and with BED, all CM types were connected to the ED psychopathology through the emotional abuse node. The association between emotional abuse and ED core symptoms (bulimia and body dissatisfaction) differed in the two groups: in people with BN, it included ineffectiveness, while in people with BED it involved impulsivity. Interoceptive awareness, an indirect measure of emotion regulation, was included in these pathways in both groups.Conclusion. In the light of literature showing that emotional abuse has a connecting role between CM and ED psychopathology also in anorexia nervosa, the present findings support the idea that emotional abuse conveys such association in all the main ED diagnoses. Ineffectiveness and impulsivity may represent the specific psychopathological dimensions connected to emotional abuse and promoting the maintenance of ED core symptoms in BN and in BED, respectively. These findings are worth of attention by clinicians.Level of evidence: Level III: Evidence obtained from well-designed cohort or case-control analytic studies


2021 ◽  
Author(s):  
Carla Barbosa Nonino ◽  
Mariana Barato ◽  
Flávia Campos Ferreira ◽  
Heitor Bernardes Pereira Delfino ◽  
Natalia Yumi Noronha ◽  
...  

Abstract Objectives: Verify the frequency of polymorphisms related to obesity and Binge Eating Disorder (BED) in DRD2 and BDNF genes in patients undergoing bariatric surgery with weight regain above 10% of the weight lost. Methods: Evaluation of 177 individuals undergoing bariatric surgery with weight regain, divided into two groups: Group 1: individuals with BED; Group 2: individuals without BED. The individuals were submitted to anthropometric evaluation, analysis of the presence of BED using a validated questionnaire, and blood collection for genotyping of the polymorphisms, rs6265 (BDNF) and rs1800497 (DRD2). The Kolmogorovi-Smirnov, t-test, chi-square, Mann Whitney, Pearson correlation were used for statistical analysis. Results: CC genotypes for rs1800497 polymorphism, and GG for rs6265 polymorphism were more frequent in patients without the disorder. The presence of at least one T allele (DRD2) and at least one A allele (BDNF) was more frequent in patients with BED. The combination of AA + GA + TT + TC genotypes prevailed in patients with the disorder. Conclusions: The CC (DRD2) and GG (BDNF) genotypes suggest protection for patients against BED, while genotypes that have at least one T allele (DRD2) and one A allele (BDNF) suggest greater risk and appear to act in synergism.Level of evidence: III (evidence obtained from case-control analytic study).


2021 ◽  
Author(s):  
Heitor Bernardes Pereira Delfino ◽  
Marcela Augusta Souza Pinhel ◽  
Flávia Campos Ferreira ◽  
Carolina Ferreira Nicoletti ◽  
Sofia Teixeira Prates Oliveira ◽  
...  

Abstract ObjectivesAnalyze the influence of Binge Eating Disorder (BED) and symptoms of depression and anxiety on anthropometric and body composition changes over five years after bariatric surgery in patients with obesity.MethodsEvaluation of 118 individuals undergoing bariatric surgery, divided into two groups: Group 1: individuals with BED; Group 2: individuals without BED. The individuals were submitted to anthropometric and body composition evaluation, and analysis of the presence of BED, depression, and anxiety according to the DSM-V and using validated questionnaires. The Kolmogorovi-Smirnov, t-test, Fisher’s, chi-square, and ANOVA were used for statistical analysis.ResultsThe groups with BED (N=61, 51,7%) and without BED (N=57, 48,3%) did not differ from each other for all sociodemographic assessed variables (p>0.05) and had similar changes in waist circumference and body composition over five years after bariatric surgery (p>0.05). On the other hand, only patients with BED had severe depression (13,11%, p=0.0079) and had a higher frequency of moderate (22.95%, p=0.0022) and severe (14.75%, p=0.0022) anxiety in the preoperative period of bariatric surgery. In addition, only the group with BED had increased weight and increased BMI in the fifth year after bariatric surgery (p<0.05).ConclusionPatients with BED had more intense symptoms of depression and anxiety, and this disorder may reappear in the postoperative period of bariatric surgery and contribute to weight gain and an increase in BMI.Level of evidence: III (evidence obtained from case-control analytic study).


Author(s):  
Alessio Maria Monteleone ◽  
Orna Tzischinsky ◽  
Giammarco Cascino ◽  
Sigal Alon ◽  
Francesca Pellegrino ◽  
...  

Abstract Purpose Childhood maltreatment (CM) experiences are associated with heightened risk of Eating disorders (EDs). The psychopathological pathways promoting this association in people with Bulimia nervosa (BN) and in those with Binge eating disorder (BED) are under-investigated. Methods One hundred and eighty-one people with BN and 144 with BED filled in the Eating Disorder Inventory-2, to measure ED psychopathology, and the Childhood Trauma Questionnaire, to assess their early traumatic experiences. Network analysis was conducted to investigate the interplay between those variables. The shortest pathways function was employed to investigate the shortest out of all routes conveying the association between CM and ED-specific symptoms. Results In both people with BN and with BED, all CM types were connected to the ED psychopathology through the emotional abuse node. The association between emotional abuse and ED-specific symptoms (bulimia and body dissatisfaction) differed in the two groups: in people with BN, it included ineffectiveness, while in people with BED, it involved impulsivity. Interoceptive awareness, an indirect measure of emotion regulation, was included in these pathways in both groups. Conclusion In the light of literature showing that emotional abuse has a connecting role between CM and ED psychopathology also in anorexia nervosa, the present findings support the idea that emotional abuse conveys such association in all the main ED diagnoses. Ineffectiveness and impulsivity may represent the specific psychopathological dimensions connected to emotional abuse and promoting the maintenance of ED-specific symptoms in BN and in BED, respectively. These findings are worth of attention by clinicians. Level of evidence Level III: evidence obtained from well-designed cohort or case–control analytic studies


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