Despite current attention to ostensibly widespread sexual abuse of children less emphasis has been directed toward identifying factors which might contribute. Accountability of professionals under mandatory reporting laws in many states now requires protection of children against inadvertent or calculated varieties of abuse. The present discussion lists factors such as family dysfunction, psychopathology, substance abuse, social ineptitude, withdrawal, and isolation, history, and psychosocial stresses and crises, which may be used to estimate the likelihood of sexual abuse of children. While determination of physical and mental abuse, neglect, endangerment, and abandonment were not the focus of the present discussion, these varieties of child abuse seem correlated with the conditions under which sexual abuse occurs. Attention to these factors—applied together with clinical intuitions and other relevant sources of information—might help professionals make more accurate assessments from which possible incidents of child sexual abuse might be averted.