PFO or UFO? The role of a patent foramen ovale in cryptogenic stroke

1991 ◽  
Vol 121 (4) ◽  
pp. 1264-1266 ◽  
Author(s):  
Rodney H. Falk
Keyword(s):  
Patent Foramen Ovale ◽  
Cryptogenic Stroke ◽  
Foramen Ovale

Stroke Prophylaxis by Percutaneous Closure of Patent Foramen Ovale and Left Atrial Appendage

2011 ◽  
Vol 6 (1) ◽  
pp. 67
Author(s):  
Antonio L Bartorelli ◽  
Claudio Tondo ◽  
◽  
Keyword(s):  
Left Atrial ◽  
Patent Foramen Ovale ◽  
Stroke Risk ◽  
Left Atrial Appendage ◽  
Cryptogenic Stroke ◽  
Atrial Appendage ◽  
Foramen Ovale ◽  
Percutaneous Procedures ◽  
Cerebrovascular Events

Innovative percutaneous procedures for stroke prevention have emerged in the last two decades. Transcatheter closure of the patent foramen ovale (PFO) is performed in patients who suffered a cryptogenic stroke or a transient ischaemic attach (TIA) in order to prevent recurrence of thromboembolic events. Percutaneous occlusion of the left atrial appendage (LAA) has been introduced to reduce stroke risk in patients with atrial fibrillation (AF). The role of PFO and LAA in the occurrence of cerebrovascular events and the interventional device-based therapies to occlude the PFO and LAA are discussed.

Patent Foramen Ovale, the Role of Antiplatelet Therapy Alone or Anticoagulant Therapy Alone Versus Device Closure for Cryptogenic Stroke: A Review of the Literature and Current Recommendations

2020 ◽  
Vol 18 (2) ◽  
pp. 135-150
Author(s):  
Harsha S. Nagarajarao ◽  
Chandra P. Ojha ◽  
Archana Kedar ◽  
Debabrata Mukherjee
Keyword(s):  
Patent Foramen Ovale ◽  
Cryptogenic Stroke ◽  
Narrow Channel ◽  
Paradoxical Embolism ◽  
Current Evidence ◽  
Foramen Ovale ◽  
The Right ◽  
The Relationship ◽  
Current Guidelines

: Cryptogenic stroke and its relation to the Patent Foramen Ovale (PFO) is a long-debated topic. Recent clinical trials have unequivocally established the relationship between cryptogenic strokes and paradoxical embolism across the PFO. This slit-like communication exists in everyone before birth, but most often closes shortly after birth. PFO may persist as a narrow channel of communication between the right and left atria in approximately 25-27% of adults. : In this review, we examine the clinical relevance of the PFO with analysis of the latest trials evaluating catheter-based closure of PFO’s for cryptogenic stroke. We also review the current evidence examining the use of antiplatelet medications versus anticoagulants for stroke prevention in those patients with PFO who do not qualify for closure per current guidelines.

scholarly journals The role of device closure of patent foramen ovale in patients with cryptogenic stroke

2020 ◽  
Vol 288 (4) ◽  
pp. 400-409
Author(s):  
M. Fukutomi ◽  
B. Wilkins ◽  
L. Søndergaard
Keyword(s):  
Patent Foramen Ovale ◽  
Cryptogenic Stroke ◽  
Foramen Ovale ◽  
Device Closure

Role of atrial fibrillation after transcatheter closure of patent foramen ovale in patients with or without cryptogenic stroke

2011 ◽  
Vol 146 (1) ◽  
pp. 17-21 ◽  
Author(s):  
Gabriele Bronzetti ◽  
Cinzia D'Angelo ◽  
Andrea Donti ◽  
Luisa Salomone ◽  
Alessandro Giardini ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Patent Foramen Ovale ◽  
Transcatheter Closure ◽  
Cryptogenic Stroke ◽  
Foramen Ovale

Cryptogenic Stroke in Children: Possible Role of Patent Foramen Ovale

2006 ◽  
Vol 37 (1) ◽  
pp. 53-56 ◽  
Author(s):  
A. Agnetti ◽  
N. Carano ◽  
E. Sani ◽  
B. Tchana ◽  
V. Allegri ◽  
...  
Keyword(s):  
Patent Foramen Ovale ◽  
Cryptogenic Stroke ◽  
Foramen Ovale

scholarly journals Patent foramen ovale and embolic cryptogenic stroke

2019 ◽  
Vol 11 (2) ◽  
pp. 4-11 ◽  
Author(s):  
A. A. Kulesh ◽  
V. V. Shestakov
Keyword(s):  
Patent Foramen Ovale ◽  
Cryptogenic Stroke ◽  
Clinical Manifestations ◽  
Diagnostic Techniques ◽  
Paradoxical Embolism ◽  
Cardiac Anomaly ◽  
Foramen Ovale ◽  
Actual Problem ◽  
Cerebral Circulation Disorders

The paper considers the actual problem of cryptogenic stroke and patent foramen ovale (PFO). It highlights the issues of pathogenesis and role of paradoxical embolism in the development of cerebral circulation disorders. The features of clinical manifestations and neuroimaging pattern of stroke in the presence of PFO are described. Ultrasound diagnostic techniques used to verify a cardiac anomaly are characterized. Approaches to establishing a cause-and-effect relationship between the presence of PFO and the development of stroke are presented. The current possibilities of secondary prevention in this category of patients, in particular the results of studies of percutaneous PFO occlusion, are discussed.

scholarly journals The Role of Patent Foramen Ovale in Cryptogenic Stroke

2016 ◽  
Vol 53 (1) ◽  
pp. 63-66 ◽  
Author(s):  
Songul Senadim ◽  
Dilek Bozkurt ◽  
Murat Cabalar ◽  
Arsida Bajrami ◽  
Vildan Yayla
Keyword(s):  
Patent Foramen Ovale ◽  
Cryptogenic Stroke ◽  
Foramen Ovale

scholarly journals A Case Series Coexistence of PFO with Other Conditions - Who’s the Culprit?

2021 ◽  
Vol 42 (3) ◽  
Author(s):  
Dessytha Nathania Hudaja ◽  
Aurea Stella Soetjipto ◽  
Queen Sugih Ariyani ◽  
Michael Soesanto ◽  
Ingrid Maria Pardede
Keyword(s):  
Atrial Fibrillation ◽  
Risk Factor ◽  
Patent Foramen Ovale ◽  
Protein C ◽  
Cryptogenic Stroke ◽  
Case Series ◽  
Review Article ◽  
Foramen Ovale ◽  
S Deficiency

Abstract.  Background: Patent foramen ovale (PFO) is a major cause of cryptogenic stroke (CS). However, it is still possible that PFO comes with those other conditions during evaluation. This paper presents a series of CS cases highly suspected due to PFO origin with each of its special presentations. Case illustration/summary of a review article: We present three cases of CS with PFO as a possible contributing factor. Case 1 showed a patient with repeated ischemic strokes that was investigated to be cryptogenic in origin. Case 2 showed CS with PFO and occult atrial fibrillation. Case 3 showed CS at a young age caused by a PFO with protein C/S deficiency. Conclusion: The role of PFO as a culprit, risk factor, or a coincidental finding in CS is still debatable and is a controversial issue. Determining PFO as a cause of CS requires a thorough consideration of clinical and PFO anatomical/morphological factors.

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