Short-term control of the pentose phosphate cycle by insulin could be modulated by the NADPHNADP ratio in rat adipocytes and hepatocytes

1987 ◽  
Vol 146 (2) ◽  
pp. 920-925 ◽  
Author(s):  
Isabel Fabregat ◽  
Elisa Revilla ◽  
Alberto Machado
1975 ◽  
Vol 14 (4) ◽  
pp. 384-390 ◽  
Author(s):  
David W. McCandless ◽  
Carol E. Cassidy ◽  
Alison D. Curley

1980 ◽  
Vol 188 (3) ◽  
pp. 859-865 ◽  
Author(s):  
J P Longenecker ◽  
J F Williams

1. Investigations of the mechanism of the non-oxidative segment of the pentose phosphate cycle in isolatd hepatocytes by prediction-labelling studies following the metabolism of [2-14C]-, [5-14C]- and [4,5,6-14C]glucose are reported. The 14C distribution patterns in glucose 6-phosphate show that the reactions of the L-type pentose pathway in hepatocytes. 2. Estimates of the quantitative contribution of the L-type pentose cycle are the exclusive form of the pentose cycle to glucose metabolism have been made. The contribution of the L-type pentose cycle to the metabolism of glucose lies between 22 and 30% in isolated hepatocytes. 3. The distribution of 14C in the carbon atoms of glucose 6-phosphate following the metabolism of [4,5,6-14C]- and [2-14C]glucose indicate that gluconeogenesis from triose phosphate and non-oxidative formation of pentose 5-phosphate do not contribute significantly to randomization of 14C in isolated hepatocytes. The transaldolase exchange reaction between fructose 6-phosphate and glyceraldehyde 3-phosphate is very active in these cells.


Microbiology ◽  
1999 ◽  
Vol 145 (7) ◽  
pp. 1743-1748 ◽  
Author(s):  
Ruslan N. Ivanovsky ◽  
Yuri I. Fal ◽  
Ivan A. Berg ◽  
Natalya V. Ugolkova ◽  
Elena N. Krasilnikova ◽  
...  

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