Regulation of dopamine D2 receptors in baboons following MPTP treatment: Correlation of in vivo and in vitro dopamine D2 receptor binding with mRNA levels

1991 ◽  
Vol 29 (9) ◽  
pp. 178
1990 ◽  
Vol 183 (4) ◽  
pp. 1414
Author(s):  
N.P.L.G. Verhoeff ◽  
M. Bobeldijk ◽  
E.A. van Royen ◽  
M.G.P. Feenstra ◽  
G.J. Boer ◽  
...  

Cephalalgia ◽  
1994 ◽  
Vol 14 (3) ◽  
pp. 235-240 ◽  
Author(s):  
C Wöber ◽  
T Brücke ◽  
C Wöber-Bingöl ◽  
S Asenbaum ◽  
P Wessely ◽  
...  

We studied in vivo the influence of flunarizine on dopamine D2 receptors and investigated whether dopamine D2 receptor blockade is involved in its antimigraine action. Eleven migraine patients, treated with flunarizine, 10 mg per day, underwent single photon emission computer tomography (SPECT) using [123I] labeled iodobenzamide, a ligand with high affinity and high specificity for D2 receptors. There was a reduction of the dopamine D2 receptor binding potential in all patients compared to age-matched controls. The efficacy of flunarizine in migraine prophylaxis failed to correlate with the degree of the dopamine D2 receptor blockade. The antimigraine action of flunarizine may not involve antidopaminergic mechanisms.


2002 ◽  
Vol 17 (3) ◽  
pp. 557-562 ◽  
Author(s):  
Guy Arnold ◽  
Klaus Tatsch ◽  
Eduardo Kraft ◽  
Wolfgang H. Oertel ◽  
Johannes Schwarz

2003 ◽  
Vol 18 (6) ◽  
pp. 895-902 ◽  
Author(s):  
Lisa Bodei ◽  
Leo J. Hofland ◽  
Diego Ferone ◽  
Cornelia M. Mooy ◽  
Johan M. Kros ◽  
...  

Synapse ◽  
2000 ◽  
Vol 37 (1) ◽  
pp. 64-70 ◽  
Author(s):  
Jogeshwar Mukherjee ◽  
Tanjore K. Narayanan ◽  
Bradley T. Christian ◽  
Bingzhi Shi ◽  
Kelly A. Dunigan ◽  
...  

2001 ◽  
Vol 28 (4) ◽  
pp. 383-389 ◽  
Author(s):  
Hongfeng Li ◽  
Franz J. Gildehaus ◽  
Stefan Dresel ◽  
Jörg T. Patt ◽  
Minghua Shen ◽  
...  

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