Electrical stimulation of the midbrain central gray facilitates lateral vestibulospinal activation of back muscle EMG in the rat

1987 ◽  
Vol 421 (1-2) ◽  
pp. 397-400 ◽  
Author(s):  
Sandra L. Cottingham ◽  
Donald W. Pfaff
Keyword(s):  
Electrical Stimulation ◽  
Back Muscle ◽  
Central Gray ◽  
Stimulation Of

Facilitation of female reproductive behavior from mesensephalic central gray in the rat

1979 ◽  
Vol 237 (5) ◽  
pp. R278-R284 ◽  
Author(s):  
Y. Sakuma ◽  
D. W. Pfaff
Keyword(s):  
Electrical Stimulation ◽  
Mesencephalic Reticular Formation ◽  
Female Rats ◽  
Motor Systems ◽  
Functional Link ◽  
Implanted Electrodes ◽  
Unilateral Stimulation ◽  
Postural Changes ◽  
Central Gray ◽  
Stimulation Of

Electrical stimulation in the mesencephalic central gray (CG) and adjacent subtectum through chronically implanted electrodes in free-moving estrogen-primed ovariectomized female rats elicited a rapid and large facilitation of the lordosis reflex in response to either male mounts or manula cutaneous stimuli. Unilateral stimulation was sufficient for this effect. The facilitation increased in a graded manner to increased stimulus intensity, and was optimally evoked by stimuli delivered at 50--150 Hz. Facilitation disappeared rapidly following the end ot electrical stimulation, and within 15 min, reflex performance returned to the prestimulation level. Lordosis facilitation appeared when no aversive responses occurred; stimulation with comparable parameters at the lateral edge of CG or in the mesencephalic reticular formation often resulted in postural changes or aversive responses but was not able to facilitate lordosis. Lordosis refelx facilitation was probably mediated by projections descending from neurons in and around the CG, and represents stimulation of a functional link between ascending somatosensory and descending motor systems for the control of lordosis behavior.

Electrical stimulation of the midbrain central gray facilitates reticulospinal activation of axial muscle EMG

1987 ◽  
Vol 97 (3) ◽  
pp. 704-724 ◽  
Author(s):  
Sandra L. Cottingham ◽  
Philip A. Femano ◽  
Donald W. Pfaff
Keyword(s):  
Electrical Stimulation ◽  
Axial Muscle ◽  
Central Gray ◽  
Stimulation Of

scholarly journals Effects of the Electrical Stimulation of the Central Gray Stratum of the Midbrain on the Blood and Myocardial Catecholamine

1966 ◽  
Vol 7 (3) ◽  
pp. 277-288 ◽  
Author(s):  
Hideo UEDA ◽  
Tetsuji IIZUKA ◽  
Hisakazu YASUDA ◽  
Yutaka TAKABATAKE ◽  
Masahiko IIZUKA ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Central Gray ◽  
Stimulation Of

Mesencephalic mechanisms for integration of female reproductive behavior in the rat

1979 ◽  
Vol 237 (5) ◽  
pp. R285-R290 ◽  
Author(s):  
Y. Sakuma ◽  
D. W. Pfaff
Keyword(s):  
Electrical Stimulation ◽  
Mesencephalic Reticular Formation ◽  
Female Rats ◽  
Motor Systems ◽  
Cuneiform Nucleus ◽  
Electrolytic Lesions ◽  
The Difference ◽  
Central Gray ◽  
Bilateral Lesions ◽  
Stimulation Of

Placement of bilateral electrolytic lesions in the mesencephalic central gray (CG) of estrogen-primed ovariectomized female rats produced an immediate decline in performance of the lordosis reflex. Lesions that destroyed the dorsal half of the CG and the adjacent subtectal region were effective. The decrease in individual animals in terms of the lordosis reflex score ranged from 20 to 100% of the prelesion performance. Such lesions abolished the facilitation of lordosis by electrical stimulation of the ventromedial nucleus of the hypothalamus. Similar abrupt losses of lordosis followed bilateral lesions of either a) the area between CG and the cuneiform nucleus of the mesencephalic reticular formation (NCf); or b) the ventrolateral quadrant of the NCf. The difference between these two lesions was that the effect of the latter could be overridden by electrical stimulation of the CG, whereas that of the former could not. We conclude that the CG is an important supraspinal component of the circuit for lordosis behavior, constituting a link between ascending somatosensory and descending motor systems for lordosis. It probably facilitates lordosis when activated by behaviorally relevant peripheral somatosensory and/or ventromedial hypothalamic inputs.

Midbrain central gray: influence on medullary sympathoexcitatory neurons and the baroreflex in rats

1992 ◽  
Vol 263 (1) ◽  
pp. R24-R33 ◽  
Author(s):  
A. J. Verberne ◽  
P. G. Guyenet
Keyword(s):  
Electrical Stimulation ◽  
Sympathetic Nerves ◽  
Ventrolateral Medulla ◽  
Arterial Blood ◽  
Pressor Responses ◽  
Central Gray ◽  
Train Stimulation ◽  
Pulse Stimulation ◽  
Site Of Stimulation ◽  
Stimulation Of

The influence of the central gray (CG) of the midbrain on the activity of 19 barosensitive sympathoexcitatory neurons of the rostral ventrolateral medulla (RVLM) and on the sympathetic vasomotor baroreflex was studied in halothane-anesthetized rats. Eighteen RVLM barosensitive units were readily activated by train stimulation of the CG, although twin-pulse stimulation was less effective (10 of 19 neurons responded). Inhibition of neurons within the RVLM by bilateral microinjection of the GABA-mimetic drug muscimol abolished the pressor responses to CG stimulation, while the accompanying lumbar nerve sympathoexcitation was converted to sympathoinhibition. In baroreceptor-denervated vagotomized animals, unilateral microinjection of muscimol into the RVLM ipsilateral or contralateral to the site of CG stimulation resulted in approximately equal attenuation of the CG sympathoexcitatory and pressor responses. In contrast, the sympathoexcitatory response to electrical stimulation of the sciatic nerve was reduced more effectively by inhibition of the RVLM contralateral to the site of stimulation. Electrical stimulation of the CG lateral and ventrolateral to the aqueduct produced sympathoexcitation [increased discharge of the greater splanchnic and lumbar sympathetic nerves (SSN and LSN)] with an increase in mean arterial blood pressure. Activation of the SSN by CG stimulation was greater than that observed for the LSN (n = 5 rats). This differential influence of the CG on the sympathetic outflow was not a result of a differential influence of the baroreflex. Electrical stimulation of the CG produced elevations of the gain and the cut-off pressure of the baroreflex for both the SSN and LSN.(ABSTRACT TRUNCATED AT 250 WORDS)

Autopsy analysis of the safety, efficacy and cartography of electrical stimulation of the central gray in humans

1986 ◽  
Vol 371 (2) ◽  
pp. 231-236 ◽  
Author(s):  
David S. Baskin ◽  
William R. Mehler ◽  
Yoshio Hosobuchi ◽  
Donald E. Richardson ◽  
John E. Adams ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Central Gray ◽  
Stimulation Of
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