Biological and pathological factors affecting plasma gamma-glutamyl transpeptidase and alkaline phosphatase activity in the elderly

Objective: The present study aimed to assess of four liver enzymes, Alanine Aminotransferase (ALT), Aspartate Transaminase (AST), Alkaline Phosphatase (ALP) and Gamma-Glutamyl Transpeptidase (GGT). Material and Methods: Based on periodontal clinical parameters, sixty four patients with chronic periodontitis (CP) and twenty four controls were enrolled in the study. Saliva and serum samples were collected and Automated Chemistry Analyzer AU 480 was employed to assess levels of enzymes. Results: Compared to healthy controls, the levels of the four enzymes were significant increased in serum of patients, especially in the severe group while in the saliva a significant increase observed only in the level of AST. Moreover, Alanine Aminotransferase (ALT), Aspartate Transaminase (AST), Alkaline Phosphatase (ALP) and Gamma-Glutamyl Transpeptidase (GGT) the levels of these enzymes in serum were significantly higher than those in saliva. Conclusion: ALT, AST, ALP and GGT serum levels are suggested to be important indicators for disease progression as well as predict the liver health.

Download Full-text

FACTORS AFFECTING SURFACE ALKALINE PHOSPHATASE ACTIVITY IN THE BROWN ALGA FUCUS SPIRALIS AT A NORTH SEA INTERTIDAL SITE (TYNE SANDS, SCOTLAND)1

Journal of Phycology ◽

10.1111/j.0022-3646.1997.00569.x ◽

1997 ◽

Vol 33 (4) ◽

pp. 569-575 ◽

Cited By ~ 27

Author(s):

Ignacio Hernandez ◽

Martin Christmas ◽

Julia M. Yelloly ◽

Brian A. Whitton

Keyword(s):

Alkaline Phosphatase ◽

Phosphatase Activity ◽

North Sea ◽

Alkaline Phosphatase Activity ◽

Brown Alga ◽

Factors Affecting ◽

Fucus Spiralis ◽

Intertidal Site

Download Full-text

Factors Affecting Alkaline Phosphatase Activity of the Marine Cyanobacterium Lyngbya majuscula

Journal of Biological Sciences ◽

10.3923/jbs.2006.931.935 ◽

2006 ◽

Vol 6 (5) ◽

pp. 931-935 ◽

Cited By ~ 4

Author(s):

Abdulrahman M. Al-Sh .

Keyword(s):

Alkaline Phosphatase ◽

Phosphatase Activity ◽

Alkaline Phosphatase Activity ◽

Marine Cyanobacterium ◽

Lyngbya Majuscula ◽

Factors Affecting

Download Full-text

A reference method for measurement of alkaline phosphatase activity in human serum.

Clinical Chemistry ◽

10.1093/clinchem/29.5.751 ◽

1983 ◽

Vol 29 (5) ◽

pp. 751-761 ◽

Cited By ~ 142

Author(s):

N W Tietz ◽

C A Burtis ◽

P Duncan ◽

K Ervin ◽

C J Petitclerc ◽

...

Keyword(s):

Alkaline Phosphatase ◽

Human Serum ◽

Phosphatase Activity ◽

Alkaline Phosphatase Activity ◽

Zinc Sulfate ◽

Metal Ion ◽

Reference Method ◽

Reaction Conditions ◽

Factors Affecting ◽

Nitrophenyl Phosphate

Abstract We present an official AACC reference method for the measurement of alkaline phosphatase, the culmination of optimization experiments conducted by a group of independent laboratories. The details of this method and evaluation of factors affecting the measurement are described. A metal ion buffer has been incorporated that maintains optimal and constant concentrations of zinc(II) and magnesium(II) ions. Final reaction conditions are: pH (30 degrees C), 10.40 +/- 0.05; 2-amino-2-methyl-1-propanol buffer, 0.35 mol/L; 4-nitrophenyl phosphate, 16.0 mmol/L; magnesium acetate, 2.0 mmol/L; zinc sulfate, 1.0 mmol/L; and N-(2-hydroxyethyl)ethylenediaminetriacetic acid, 2.0 mmol/L.

Download Full-text