Clinical utility of long latency ‘cognitive’ event-related potentials (P3): the cons

1990 ◽  
Vol 76 (1) ◽  
pp. 6-12 ◽  
Author(s):  
Adolf Pfefferbaum ◽  
Judith M. Ford ◽  
Helena C. Kraemer
2021 ◽  
Vol 11 (7) ◽  
pp. 835
Author(s):  
Alexander Rokos ◽  
Richard Mah ◽  
Rober Boshra ◽  
Amabilis Harrison ◽  
Tsee Leng Choy ◽  
...  

A consistent limitation when designing event-related potential paradigms and interpreting results is a lack of consideration of the multivariate factors that affect their elicitation and detection in behaviorally unresponsive individuals. This paper provides a retrospective commentary on three factors that influence the presence and morphology of long-latency event-related potentials—the P3b and N400. We analyze event-related potentials derived from electroencephalographic (EEG) data collected from small groups of healthy youth and healthy elderly to illustrate the effect of paradigm strength and subject age; we analyze ERPs collected from an individual with severe traumatic brain injury to illustrate the effect of stimulus presentation speed. Based on these critical factors, we support that: (1) the strongest paradigms should be used to elicit event-related potentials in unresponsive populations; (2) interpretation of event-related potential results should account for participant age; and (3) speed of stimulus presentation should be slower in unresponsive individuals. The application of these practices when eliciting and recording event-related potentials in unresponsive individuals will help to minimize result interpretation ambiguity, increase confidence in conclusions, and advance the understanding of the relationship between long-latency event-related potentials and states of consciousness.


2016 ◽  
Vol 10 ◽  
pp. 192-197 ◽  
Author(s):  
Vasilios K. Kimiskidis ◽  
Vasileios Papaliagkas ◽  
Kyriaki Sotirakoglou ◽  
Zoi K. Kouvatsou ◽  
Victoria K. Kapina ◽  
...  

Author(s):  
Tatsuomi Fukushima ◽  
Eiichiro Uyama ◽  
Makoto Uchino ◽  
Hiroaki Okabe ◽  
Ikuko Kondo ◽  
...  

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