Control of mediator release from the human alveolar macrophage: Role of cyclic AMP

1990 ◽  
Vol 183 (2) ◽  
pp. 621 ◽  
Author(s):  
R.W. Fuller ◽  
R.W. Fuller
1994 ◽  
Vol 307 (6) ◽  
pp. 408-413
Author(s):  
George Thomas ◽  
Rodney P. Swartz ◽  
Henry Yeager ◽  
Peter W. Ramwell

1993 ◽  
Vol 4 (6) ◽  
pp. 204-209 ◽  
Author(s):  
Wolfgang Schmid ◽  
Doris Nitsch ◽  
Michael Boshart ◽  
Günther Schütz

1980 ◽  
Vol 59 (3) ◽  
pp. 14P-14P ◽  
Author(s):  
A. P. Greening ◽  
A. D. M. Rees ◽  
D. B. Lowrie

1992 ◽  
Vol 283 (1) ◽  
pp. 261-264 ◽  
Author(s):  
N Casals ◽  
N Roca ◽  
M Guerrero ◽  
G Gil-Gómez ◽  
J Ayté ◽  
...  

We have explored the role of mitochondrial 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase in regulating ketogenesis. We had previously cloned the cDNA for mitochondrial HMG-CoA synthase and have now studied the regulation in vivo of the expression of this gene in rat liver. The amount of processed mitochondrial HMG-CoA synthase mRNA is rapidly changed in response to cyclic AMP, insulin, dexamethasone and refeeding, and is greatly increased by starvation, fat feeding and diabetes. We conclude that one point of ketogenic control is exercised at the level of genetic expression of mitochondrial HMG-CoA synthase.


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