Visual acuity as a reinforcement in learning to control pupil size

1962 ◽  
Vol 5 (5) ◽  
pp. 428-433 ◽  
Author(s):  
Clark J. Bailey ◽  
Lloyd Guth
Keyword(s):  
2007 ◽  
Vol 104 (1) ◽  
pp. 267-272 ◽  
Author(s):  
Tetsuo Ueda ◽  
Yoshiaki Nawa ◽  
Masahiro Okamoto ◽  
Yoshiaki Hara

1979 ◽  
Vol 56 (5) ◽  
pp. 315-323 ◽  
Author(s):  
DAVID A. ATCHISON ◽  
GEORGE SMITH ◽  
NATHAN EFRON
Keyword(s):  

2004 ◽  
Author(s):  
Silvia A. Comastri ◽  
Rodolfo M. Echarri ◽  
T. Pfortner
Keyword(s):  

2011 ◽  
Vol 96 (2) ◽  
pp. 267-270 ◽  
Author(s):  
Kazutaka Kamiya ◽  
Hidenaga Kobashi ◽  
Kimiya Shimizu ◽  
Takushi Kawamorita ◽  
Hiroshi Uozato

2018 ◽  
Vol 41 ◽  
pp. S23
Author(s):  
Kathy Dumbleton ◽  
Michel Guillon ◽  
Panagiotis Theodoratos ◽  
C. Benjamin Wooley ◽  
Kurt Moody

2014 ◽  
Vol 30 (7) ◽  
pp. 448-453 ◽  
Author(s):  
Minoru Tomita ◽  
Tomomi Kanamori ◽  
George O. Waring ◽  
Tukezban Huseynova

2010 ◽  
Vol 26 (5) ◽  
pp. 378-380 ◽  
Author(s):  
Takushi Kawamorita ◽  
Hiroshi Uozato ◽  
Tomoya Handa ◽  
Misae Ito ◽  
Kimiya Shimizu

2020 ◽  
Vol 185 (Supplement_1) ◽  
pp. 435-442 ◽  
Author(s):  
Micah Kinney ◽  
Andrew D Johnson ◽  
Michael Reddix ◽  
Mary B McCann

ABSTRACT Introduction First responders and those who work with organophosphate (OP) compounds can experience ocular symptoms similar to those caused by exposure to low levels of nerve agents. This study was designed to examine the efficacy of a safe, clinically available, simulant that reproduces ocular symptoms associated with low-level OP exposure. Among these ocular symptoms are a constriction of the pupils (miosis), decreased visual acuity, and changes in accommodation. Materials and Methods Volunteers aged 18–40 were assigned to groups receiving either a two-drop or three-drop dose of FDA approved 2% pilocarpine ophthalmic solution. Baseline visual performance measurements were taken before eye drop instillation and a timer was started following the first drop of pilocarpine. Once eye drops were administered, visual performance including distant and near vision, pupil size, and accommodation were measured every 5 minutes for 2 hours. Results Both groups experienced significant miosis in excess of 90 minutes. Visual acuity was significantly reduced because of accommodative changes. The three-drop group experienced longer lasting combined effects when compared to the two-drop group. Conclusions 2% pilocarpine ophthalmic solution can safely simulate major ocular symptoms of OP exposure for behavioral research studies for at least 60 minutes.


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