The extracellular matrix of rat spinal cord: A comparative study on the localization of hyaluronic acid, glial hyaluronate-binding protein, and chondroitin sulfate proteoglycan

1992 ◽  
Vol 117 (1) ◽  
pp. 90-93 ◽  
Author(s):  
A. Bignami ◽  
R. Asher ◽  
G. Perides
Keyword(s):  
Spinal Cord ◽  
Extracellular Matrix ◽  
Hyaluronic Acid ◽  
Comparative Study ◽  
Chondroitin Sulfate ◽  
Binding Protein ◽  
Chondroitin Sulfate Proteoglycan ◽  
Sulfate Proteoglycan ◽  
Rat Spinal Cord

Detection of chondroitin sulfates and decorin in developing fetal and neonatal rat lung

2002 ◽  
Vol 282 (3) ◽  
pp. L484-L490 ◽  
Author(s):  
Yiqiong Wang ◽  
Kaori Sakamoto ◽  
Jody Khosla ◽  
Philip L. Sannes
Keyword(s):  
Extracellular Matrix ◽  
Chondroitin Sulfate ◽  
Wide Distribution ◽  
Neonatal Rat ◽  
Chondroitin Sulfate Proteoglycan ◽  
Sulfate Proteoglycan ◽  
Rat Lung ◽  
Adult Rats ◽  
Chondroitin Sulfates ◽  
Monospecific Antibodies

Chondroitin sulfates and their related proteoglycans are components of extracellular matrix that act as key determinants of growth and differentiation characteristics of developing lungs. Changes in their immunohistochemical distribution during progressive organ maturation were examined with monospecific antibodies to chondroitin sulfate, a nonbasement membrane chondroitin sulfate proteoglycan, and the specific chondroitin sulfate-containing proteoglycan decorin in whole fetuses and lungs from newborn and adult rats. Alveolar and airway extracellular matrix immunostained heavily in the prenatal rat for both chondroitin sulfate and chondroitin sulfate proteoglycan, whereas decorin was confined to developing airways and vessels. These sites retained their respective levels of reactivity with all antibodies through 1–10 days postnatal but thereafter became progressively more diminished and focal in alveolar regions. The heavy staining seen early in development was interpreted to reflect a significant and wide distribution of chondroitin sulfates, chondroitin sulfate proteoglycans, and decorin in rapidly growing tissues, whereas the reduced and more focal reactivity observed at later time points coincided with known focal patterns of localization of fibrillar elements of the extracellular matrix and a more differentiated state.

Interferon-γ Decreases Chondroitin Sulfate Proteoglycan Expression and Enhances Hindlimb Function after Spinal Cord Injury in Mice

2010 ◽  
Vol 27 (12) ◽  
pp. 2283-2294 ◽  
Author(s):  
Takayuki Fujiyoshi ◽  
Takekazu Kubo ◽  
Carmen C.M. Chan ◽  
Masao Koda ◽  
Akihiko Okawa ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Chondroitin Sulfate ◽  
Interferon Γ ◽  
Chondroitin Sulfate Proteoglycan ◽  
Sulfate Proteoglycan ◽  
Cord Injury

Chondroitin sulfate proteoglycan-based extracellular matrix in chicken (Gallus domesticus) brain

2009 ◽  
Vol 1275 ◽  
pp. 10-23 ◽  
Author(s):  
Markus Morawski ◽  
Alán Alpár ◽  
Gert Brückner ◽  
Anja Fiedler ◽  
Carsten Jäger ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Chondroitin Sulfate ◽  
Gallus Domesticus ◽  
Chondroitin Sulfate Proteoglycan ◽  
Sulfate Proteoglycan
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