Total deposition of aerosol particles in the human respiratory tract for nose and mouth breathing

The deposition of aerosol in the human respiratory tract was calculated as a function of the particle size and particle density of the aerosol, the manner of breathing, and various parameters which control the degree of mixing of inspired air with the dead space air and with the lung air. The computations were performed on an electronic computer, which allowed a full analysis of the effects of the various parameters. Agreement between the computed total deposition curves, and published experimental data was very satisfactory. The computed curves exhibited the minimum in total deposition previously established experimentally, in the region of 0.3 μ. The maximum in the alveolar deposition curve was about 1 μ for particles of unit density, confirming the results of Brown, Cook, Ney, and Hatch for nose breathing. Its position was a function of the density of the aerosol particles, but was relatively insensitive to the tidal volume and other breathing parameters. The opposite held in regard to the value of the maximum, which was totally uninfluenced by the particle density, but was affected by the breathing parameters.

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Total deposition of aerosol particles in the respiratory tract of children during spontaneous and controlled mouth breathing

Journal of Aerosol Science ◽

10.1016/0021-8502(92)90448-5 ◽

1992 ◽

Vol 23 ◽

pp. 457-460 ◽

Cited By ~ 26

Author(s):

Ch.F. Schiller-Scotland ◽

R. Hlawa ◽

J. Gebhart ◽

R. Wönne ◽

J. Heyder

Keyword(s):

Respiratory Tract ◽

Aerosol Particles ◽

Mouth Breathing ◽

Total Deposition

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Factors influencing total deposition of ultrafine aerosol particles in the human respiratory tract

Journal of Aerosol Science ◽

10.1016/0021-8502(86)90098-4 ◽

1986 ◽

Vol 17 (3) ◽

pp. 328-332 ◽

Cited By ~ 28

Author(s):

Ch.F. Schiller ◽

J. Gebhart ◽

J. Heyder ◽

G. Rudolf ◽

W. Stahlhofen

Keyword(s):

Respiratory Tract ◽

Aerosol Particles ◽

Human Respiratory Tract ◽

Total Deposition ◽

Factors Influencing ◽

Ultrafine Aerosol

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Prediction of Aerosol Deposition in the Human Respiratory Tract via Computational Models: A Review with Recent Updates

Atmosphere ◽

10.3390/atmos11020137 ◽

2020 ◽

Vol 11 (2) ◽

pp. 137 ◽

Cited By ~ 3

Author(s):

Vu Khac Hoang Bui ◽

Ju-Young Moon ◽

Minhe Chae ◽

Duckshin Park ◽

Young-Chul Lee

Keyword(s):

Respiratory Tract ◽

Particle Deposition ◽

Computational Models ◽

Aerosol Particles ◽

Three Dimensional ◽

Aerosol Deposition ◽

Research Area ◽

Human Respiratory Tract

The measurement of deposited aerosol particles in the respiratory tract via in vivo and in vitro approaches is difficult due to those approaches’ many limitations. In order to overcome these obstacles, different computational models have been developed to predict the deposition of aerosol particles inside the lung. Recently, some remarkable models have been developed based on conventional semi-empirical models, one-dimensional whole-lung models, three-dimensional computational fluid dynamics models, and artificial neural networks for the prediction of aerosol-particle deposition with a high accuracy relative to experimental data. However, these models still have some disadvantages that should be overcome shortly. In this paper, we take a closer look at the current research trends as well as the future directions of this research area.

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