Selective removal of plasma low density lipoprotein with the HELP system: biweekly versus weekly therapy

1995 ◽  
Vol 114 (2) ◽  
pp. 203-211 ◽  
Author(s):  
Daniel M. Lane ◽  
Walter J. McConathy ◽  
L.O. Laughlin ◽  
Philip C. Comp ◽  
Beat von Albertini ◽  
...  
Keyword(s):  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Selective Removal ◽  
Low Density ◽  
Weekly Therapy ◽  
Help System

scholarly journals SP414A NOVEL ADSORBENTS FOR SELECTIVE REMOVAL OF LOW DENSITY LIPOPROTEIN

2016 ◽  
Vol 31 (suppl_1) ◽  
pp. i229-i229
Author(s):  
Liu Qiang ◽  
Sun Si ◽  
Yang Tingting ◽  
Han Mei ◽  
Lin Liping ◽  
...  
Keyword(s):  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Selective Removal ◽  
Low Density

Chitosan Adsorbents Carrying Amino Acids for Selective Removal of Low Density Lipoprotein

2004 ◽  
Vol 32 (2) ◽  
pp. 303-313 ◽  
Author(s):  
Guoqi Fu ◽  
Haofeng Yu ◽  
Zhi Yuan ◽  
Bin Liu ◽  
Bin Shen ◽  
...  
Keyword(s):  
Amino Acids ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Selective Removal ◽  
Low Density

Intralysosomal Accumulation of Colloidal Gold-Low Density Lipoprotein Conjugates in Chloroquine-Treated Fibroblasts

1985 ◽  
Vol 43 ◽  
pp. 546-547 ◽  
Author(s):  
Dean A. Handley ◽  
Cynthia M. Arbeeny ◽  
Larry D. Witte
Keyword(s):  
Colloidal Gold ◽  
Cultured Cells ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Coated Vesicle ◽  
Low Density ◽  
Cholesterol Esters ◽  
Cultured Fibroblasts ◽  
Surface Receptors ◽  
Ldl Particles

Low density lipoproteins (LDL) are the major cholesterol carrying particles in the blood. Using cultured cells, it has been shown that LDL particles interact with specific surface receptors and are internalized via a coated pit-coated vesicle pathway for lysosomal catabolism. This (Pathway has been visualized using LDL labeled to ferritin or colloidal gold. It is now recognized that certain lysomotropic agents, such as chloroquine, inhibit lysosomal enzymes that degrade protein and cholesterol esters. By interrupting cholesterol ester hydrolysis, chloroquine treatment results in lysosomal accumulation of cholesterol esters from internalized LDL. Using LDL conjugated to colloidal gold, we have examined the ultrastructural effects of chloroquine on lipoprotein uptake by normal cultured fibroblasts.

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