Research design considerations for linkage studies of affective disorders using recombinant DNA markers

1987 ◽  
Vol 21 (4) ◽  
pp. 551-557 ◽  
Author(s):  
Kenneth K. Kidd
Keyword(s):  
Research Design ◽  
Dna Markers ◽  
Affective Disorders ◽  
Recombinant Dna ◽  
Linkage Studies ◽  
Design Considerations

scholarly journals Research design considerations for chronic pain prevention clinical trials

Pain ◽  
2015 ◽  
Vol 156 (7) ◽  
pp. 1184-1197 ◽  
Author(s):  
Jennifer S. Gewandter ◽  
Robert H. Dworkin ◽  
Dennis C. Turk ◽  
John T. Farrar ◽  
Roger B. Fillingim ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Clinical Trials ◽  
Research Design ◽  
Design Considerations

Qualitative Diary Research Design

2018 ◽  
Author(s):  
Lauri L. Hyers
Keyword(s):  
Research Design ◽  
Past Research ◽  
Basic Design ◽  
Design Considerations ◽  
Diary Research ◽  
Participant Selection ◽  
Diary Studies ◽  
Research Studies

This chapter discusses basic design considerations for qualitative diary studies that involve either archival or solicited diaries. After a brief overview of the unique types of data diaries can provide, a separate discussion is provided for archival and solicited diary studies. Archival diary researchers will need to locate diaries that have already been written for personal reasons or for past research studies. They will not have any say in the format of these pre-existing diaries. Solicited diary researchers, in contrast, must plan for participant selection and recruitment and the structure and timing of the diary entries. The chapter concludes with a discussion of potential supporting documents for both archival and solicited diary studies.

scholarly journals Linkage studies of major affective disorders: the impact of the extension of pedigrees

1992 ◽  
Vol 7 (3) ◽  
pp. 145-146
Author(s):  
AC Bruni ◽  
MP Montesi ◽  
R Manfredi ◽  
A Di Cello ◽  
G Gei ◽  
...  
Keyword(s):  
Affective Disorders ◽  
Linkage Studies ◽  
The Impact

Sampling strategy in linkage studies of affective disorders

1990 ◽  
Vol 20 (3) ◽  
pp. 573-579 ◽  
Author(s):  
M. Leboyer ◽  
M. C. Babron ◽  
F. Clerget-Darpoux
Keyword(s):  
Genetic Markers ◽  
Genetic Heterogeneity ◽  
Affective Disorders ◽  
Sampling Strategy ◽  
Linkage Studies ◽  
Chromosome X ◽  
Nuclear Families ◽  
Bipolar Patients ◽  
Degree Of Heterogeneity

SynopsisEvidence of linkage in families of bipolar patients has so far been identified with genetic markers on chromosome X and 11. However, replications of these data have not consistently been reported in either case, which favours the hypothesis of genetic heterogeneity. Therefore, we have tried to outline a sampling strategy for linkage replication in affective disorders. We estimated the average number of nuclear families required to replicate X or 11 linkage as a function of the degree of heterogeneity as well as the number to prove heterogeneity given that linkage exists. The results are presented and discussed.

Research design considerations for confirmatory chronic pain clinical trials: IMMPACT recommendations

Pain ◽  
2010 ◽  
Vol 149 (2) ◽  
pp. 177-193 ◽  
Author(s):  
Robert H. Dworkin ◽  
Dennis C. Turk ◽  
Sarah Peirce-Sandner ◽  
Ralf Baron ◽  
Nicholas Bellamy ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Clinical Trials ◽  
Research Design ◽  
Design Considerations

scholarly journals Research Design Considerations

2016 ◽  
Vol 8 (1) ◽  
pp. 97-98 ◽  
Author(s):  
Sarah Wright ◽  
Bridget C. O'Brien ◽  
Laura Nimmon ◽  
Marcus Law ◽  
Maria Mylopoulos
Keyword(s):  
Research Design ◽  
Design Considerations
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