Bromocriptine inhibits in vivo free fatty acid oxidation and hepatic glucose output in seasonally obese hamsters (Mesocricetus auratus)

Metabolism ◽  
1995 ◽  
Vol 44 (10) ◽  
pp. 1349-1355 ◽  
Author(s):  
Anthony H. Cincotta ◽  
Albert H. Meier
Diabetes ◽  
1995 ◽  
Vol 44 (9) ◽  
pp. 1038-1045 ◽  
Author(s):  
K. Rebrin ◽  
G. M. Steil ◽  
L. Getty ◽  
R. N. Bergman

2001 ◽  
Vol 86 (4) ◽  
pp. 1638-1644
Author(s):  
E. E. Blaak ◽  
B. H. R. Wolffenbuttel ◽  
W. H. M. Saris ◽  
M. M. A. L. Pelsers ◽  
A. J. M. Wagenmakers

Diabetes ◽  
1995 ◽  
Vol 44 (9) ◽  
pp. 1038-1045 ◽  
Author(s):  
K. Rebrin ◽  
G. M. Steil ◽  
L. Getty ◽  
R. N. Bergman

Author(s):  
Giuseppe Rosano ◽  
Andrew Coats

Heart failure is associated with altered cardiac metabolism, in part, due to maladaptive mechanisms, in part secondary to comorbidities such as diabetes and ischaemic heart disease. The metabolic derangements taking place in heart failure are not limited to the cardiac myocytes, but extend to skeletal muscles and the vasculature causing changes that contribute to the worsening of exercise capacity. Modulation of cardiac metabolism with partial inhibition of free fatty acid oxidation has been shown to be beneficial in patients with heart failure. At the present, the bulk of evidence for this class of drugs comes from Trimetazidine. Newer compounds partially inhibiting free fatty acid oxidation or facilitating the electron transport on the mitochondrial cristae are in early phase of their clinical development.


1994 ◽  
Vol 87 (s1) ◽  
pp. 94-95
Author(s):  
LS Sidossis ◽  
AR Coggan ◽  
A Gastaldelli ◽  
RR Wolfe

2007 ◽  
Vol 4 (4) ◽  
pp. 236-242 ◽  
Author(s):  
Gabriele Fragasso ◽  
Roberto Spoladore ◽  
Giorgio Bassanelli ◽  
Amarild Cuko ◽  
Chiara Montano ◽  
...  

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