Medial amygdala lesions in male rats reduce aggressive behavior: interference with experience

1987 ◽  
Vol 41 (2) ◽  
pp. 99-102 ◽  
Author(s):  
J.D. Vochteloo ◽  
J.M. Koolhaas
Keyword(s):  
Aggressive Behavior ◽  
Male Rats ◽  
Medial Amygdala ◽  
Amygdala Lesions

Remodeling of the number and structure of dendritic spines in the medial amygdala: From prepubertal sexual dimorphism to puberty and effect of sexual experience in male rats

2018 ◽  
Vol 48 (2) ◽  
pp. 1851-1865 ◽  
Author(s):  
Mariana Zancan ◽  
Rick Shandler R. Cunha ◽  
Francielle Schroeder ◽  
Léder L. Xavier ◽  
Alberto A. Rasia‐Filho
Keyword(s):  
Sexual Dimorphism ◽  
Dendritic Spines ◽  
Sexual Experience ◽  
Male Rats ◽  
Medial Amygdala

Medial amygdala and aggressive behavior: Interaction between testosterone and vasopressin

1990 ◽  
Vol 16 (3-4) ◽  
pp. 223-229
Author(s):  
J. M. Koolhaas ◽  
T. H. C. Van Den Brink ◽  
B. Roozendaal ◽  
F. Boorsma
Keyword(s):  
Aggressive Behavior ◽  
Medial Amygdala

scholarly journals Ultrastructural features of neurons and synaptic contacts in the posterodorsal medial amygdala of adult male rats

2006 ◽  
Vol 208 (5) ◽  
pp. 565-575 ◽  
Author(s):  
E. E. S. Hermel ◽  
M. C. Faccioni-Heuser ◽  
S. Marcuzzo ◽  
A. A. Rasia-Filho ◽  
M. Achaval
Keyword(s):  
Adult Male ◽  
Male Rats ◽  
Medial Amygdala ◽  
Synaptic Contacts

1906 Medial amygdala lesions prevent psychogenic erections, but not reflexive erections, in rats

1993 ◽  
Vol 18 ◽  
pp. S213
Author(s):  
Yasuhiko Kondo ◽  
Yian-Cheng Liu ◽  
Benjamin D. Sachs ◽  
Korehito Yamanouchi
Keyword(s):  
Medial Amygdala ◽  
Amygdala Lesions

Genomic and non-genomic effects of glucocorticoids on aggressive behavior in male rats

2004 ◽  
Vol 29 (5) ◽  
pp. 618-635 ◽  
Author(s):  
Éva Mikics ◽  
Menno R. Kruk ◽  
József Haller
Keyword(s):  
Aggressive Behavior ◽  
Male Rats ◽  
Genomic Effects

Medial amygdala lesions differentially influence stress responsivity and sensorimotor gating in rats

2010 ◽  
Vol 99 (3) ◽  
pp. 395-401 ◽  
Author(s):  
Christiaan H. Vinkers ◽  
Elisabeth Y. Bijlsma ◽  
Lotte C. Houtepen ◽  
Koen G.C. Westphal ◽  
Jan G. Veening ◽  
...  
Keyword(s):  
Sensorimotor Gating ◽  
Medial Amygdala ◽  
Stress Responsivity ◽  
Amygdala Lesions

scholarly journals Testosterone-Estradiol Filled Polydimethylsiloxane Subdermal Implants: Effect on Fertility and Masculine Sexual and Aggressive Behavior of Male Rats

1979 ◽  
Vol 21 (4) ◽  
pp. 765-772 ◽  
Author(s):  
Larry L. Ewing ◽  
Roger A. Gorski ◽  
Robert J. Sbordone ◽  
Julia V. Tyler ◽  
Claude Desjardins ◽  
...  
Keyword(s):  
Aggressive Behavior ◽  
Male Rats ◽  
Subdermal Implants

scholarly journals Modelling sexual violence in male rats: The sexual aggression test (SxAT)

2021 ◽  
Author(s):  
Vinicius Elias de Moura Oliveira ◽  
Trynke R de Jong ◽  
Inga Neumann
Keyword(s):  
Aggressive Behavior ◽  
Sexual Aggression ◽  
Wistar Rats ◽  
Insular Cortex ◽  
Receptive Female ◽  
Male Rats ◽  
Aggression Test ◽  
Male Wistar Rats ◽  
Series Of Experiments ◽  
Social Decision Making

Sexual assault and rape are crimes that impact victims worldwide. Although the psychosocial and eco-evolutionary factors associated with this antisocial behavior have repeatedly been studied, the underlying neurobiological mechanisms are still unknown mainly due to the lack of an appropriate animal model of sexual aggression (SxA). Here, we established a novel paradigm to provoke and subsequently assess SxA in adult male Wistar rats: the sexual aggression test (SxAT). Briefly, male Wistar rats are sexually aroused by a receptive female, which is exchanged by a non-receptive female immediately after the first intromission. This protocol elicits forced mounting (FM) and aggressive behavior (AB) towards the non-receptive female to different degrees, which can be scored. In a series of experiments we can show that SxA behavior is a relatively stable trait in rats and correlates positively with sexual motivation. Rats with innate abnormal anxiety and aggressive behavior also show abnormal SxA behavior. In addition, central infusion of oxytocin moderately inhibits AB, but increases FM. Finally, we identified the agranular insular cortex to be specifically activated by SxA, and inhibition of this region mildly decreased AB during the SxAT. Altogether, the SxAT is a paradigm that can be readily implemented in behavioral laboratories as a valuable tool to find answers regarding the biological mechanisms underlying SxA in humans, as well as social decision-making in general.

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