Instrumentation for complex fluid flows

1988 ◽  
Vol 9 (2) ◽  
pp. 258
Author(s):  
R.J. Adrian
Keyword(s):  
1985 ◽  
Vol 113 (1) ◽  
pp. 32-37 ◽  
Author(s):  
Leonid Shtilman ◽  
Evgeny Levich ◽  
Steven A. Orszag ◽  
Richard B. Pelz ◽  
Arkady Tsinober
Keyword(s):  

2020 ◽  
Author(s):  
Cynthia Hajal ◽  
Lina Ibrahim ◽  
Jean Carlos Serrano ◽  
Giovanni S. Offeddu ◽  
Roger D. Kamm

ABSTRACTThroughout the process of metastatic dissemination, tumor cells are continuously subjected to mechanical forces resulting from complex fluid flows due to changes in pressures in their local microenvironments. While these forces have been associated with invasive phenotypes in 3D matrices, their role in key steps of the metastatic cascade, namely extravasation and subsequent interstitial migration, remains poorly understood. In this study, an in vitro model of the human microvasculature was employed to subject tumor cells to physiological luminal, trans-endothelial, and interstitial flows to evaluate their effects on those key steps of metastasis. Luminal flow promoted the extravasation potential of tumor cells, possibly as a result of their increased intravascular migration speed. Trans-endothelial flow increased the speed with which tumor cells transmigrated across the endothelium as well as their migration speed in the matrix following extravasation. In addition, tumor cells possessed a greater propensity to migrate in close proximity to the endothelium when subjected to physiological flows, which may promote the successful formation of metastatic foci. These results show important roles of fluid flow during extravasation and invasion, which could determine the local metastatic potential of tumor cells.


2017 ◽  
Vol 814 ◽  
pp. 1-4 ◽  
Author(s):  
J. Nathan Kutz

It was only a matter of time before deep neural networks (DNNs) – deep learning – made their mark in turbulence modelling, or more broadly, in the general area of high-dimensional, complex dynamical systems. In the last decade, DNNs have become a dominant data mining tool for big data applications. Although neural networks have been applied previously to complex fluid flows, the article featured here (Ling et al., J. Fluid Mech., vol. 807, 2016, pp. 155–166) is the first to apply a true DNN architecture, specifically to Reynolds averaged Navier Stokes turbulence models. As one often expects with modern DNNs, performance gains are achieved over competing state-of-the-art methods, suggesting that DNNs may play a critically enabling role in the future of modelling complex flows.


Author(s):  
Hugues Digonnet ◽  
Olivier Basset ◽  
Luisa Silva ◽  
Thierry Coupez

In this paper we present numerical simulations of complex fluid flows performed on a PC cluster. These simulations were possible thanks to a parallelization strategy that is transparent and efficient: each developer does not need to know a parallel programming library and its specific language. Instead, he uses purely SPMD tools to build their applications. Two examples are shown, as well as the computational results obtained for problems that need the resolution of linear Systems of over 7 million of unknowns.


Author(s):  
Dragan Mandić ◽  
◽  
◽  

The object of this paper is to model the complex fluid motion that is caused by the rotational motion of rotary disks. In doing so, the rotary disk occupied a normal or parallel position with respect to the fluid flow axis. Various designs of rotary bodies were also applied, with the introduction of fluid through the central opening inside the impeller of the rotating bodies and with the introduction of fluid on the outer surfaces of these impellers (surfaces limited by the largest diameters of the rotary discs). During the modeling, different initial conditions for different structures and positions of rotating bodies were adopted. For each individual stream, flow diagrams are given through a cylindrical fluid stream whose translational motion is complicated by the rotational motion of the friction disks in its flow. The results obtained give a clear picture of the disturbances and changes in the front of the fluid motion wave which can be used as a necessary experience in the design of circulating technological systems.


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