Schistosoma mansoni: Cell-mediated immunity evaluated by antigen-induced leukocyte adherence inhibition assay

1985 ◽  
Vol 9 (1) ◽  
pp. 39-42 ◽  
Author(s):  
J.A. Nogueira-Machado ◽  
E. Novato-Silva ◽  
M.F. Souza ◽  
G.V. Kritz
Keyword(s):  
Schistosoma Mansoni ◽  
Cell Mediated Immunity ◽  
Leukocyte Adherence ◽  
Inhibition Assay ◽  
Leukocyte Adherence Inhibition ◽  
Adherence Inhibition

The Lai Test in Specific Immune-Reactivity Studies of Fibrocystic Breast Disease

1982 ◽  
Vol 68 (4) ◽  
pp. 291-294
Author(s):  
Giorgio Cavallini ◽  
Gilberte Berti
Keyword(s):  
Skeletal Muscle ◽  
Gastric Carcinoma ◽  
Breast Disease ◽  
Immune Reactivity ◽  
Leukocyte Adherence ◽  
Inhibition Assay ◽  
Fibrocystic Disease ◽  
Fibrocystic Breast Disease ◽  
Leukocyte Adherence Inhibition ◽  
Adherence Inhibition

Sixteen cases of fibrocystic breast disease at different histopathologic stage were examined with the leukocyte adherence inhibition assay. Skeletal muscle and gastric carcinoma extracts were used as controls. The glass adherence of leukocytes from patients affected by fibrocystic breast disease was more inhibited when extracts from breasts with fibrocystic disease were used rather than control extracts. Nonadherence indexes (NAIs) were high in 8 cases, around 20 in 4 cases, a little above zero in 2 cases and below zero in 2 cases. NAIs were related to the histopathologic stage: the highest NAIs were found in 8 cases of classic fibrocystic disease, the lowest in 1 case of simple breast fibrosis.

Leukocyte Adherence Inhibition Assay in the Diagnosis and Follow-Up of Colorectal Cancer Patients

Oncology ◽  
1986 ◽  
Vol 43 (1) ◽  
pp. 23-26 ◽  
Author(s):  
Z. Weisman ◽  
A. Shani ◽  
A. Fink ◽  
A. Shindel ◽  
A. Sela ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patients ◽  
Leukocyte Adherence ◽  
Inhibition Assay ◽  
Leukocyte Adherence Inhibition ◽  
Colorectal Cancer Patients ◽  
Adherence Inhibition

Leukocyte Adherence Inhibition Test: Cell-Mediated Reactivity to Tumor Antigens in Colorectal and Lung Tumor Long Survivors

1991 ◽  
Vol 77 (6) ◽  
pp. 500-505
Author(s):  
Massimo Fazio ◽  
Felice Calabrese ◽  
Michele Camandona ◽  
Franco Correggia ◽  
Sara Giacomasso ◽  
...  
Keyword(s):  
Colorectal Adenocarcinoma ◽  
Tumor Antigens ◽  
Lung Tumor ◽  
Prognostic Significance ◽  
Lung Squamous Cell Carcinoma ◽  
Cell Mediated Immunity ◽  
Leukocyte Adherence ◽  
Leukocyte Adherence Inhibition ◽  
Blocking Factors ◽  
Adherence Inhibition

Cell-mediated Immunity versus tumor antigens (cytosols) of the same histotype and site was evaluated by means of the leukocyte adherence Inhibition (LAI) test in 44 colorectal adenocarcinoma and 17 lung squamous-cell carcinoma patients 3–10 years after surgical resection. LAI-positivity was observed in 17/44 (38.6 %) and 13/17 (76.5 %) patients, respectively, together with serum blocking factors in 7/17 (41.2%) compared to 0/13. These results indicate that a high percentage of long survivors retain an immunologic memory of the tumor antigen to which they have been exposed. The prognostic significance of serum blocking factors is less clear.

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