Identification and characterization of glycosylphosphatidylinositol-linked Schistosoma mansoni adult worm immunogens

1990 ◽  
Vol 38 (2) ◽  
pp. 199-209 ◽  
Author(s):  
S SAUMA ◽  
M STRAND
1989 ◽  
Vol 69 (2) ◽  
pp. 249-262 ◽  
Author(s):  
Shohreh Miller ◽  
David M. Rekosh ◽  
Philip T. LoVerde

1996 ◽  
Vol 76 (1-2) ◽  
pp. 73-82 ◽  
Author(s):  
D. Kiang ◽  
N.E. El Ghazalie ◽  
A.M. Medhat ◽  
M. Abdel-Fattah ◽  
A.M. Karim ◽  
...  

Parasitology ◽  
1987 ◽  
Vol 94 (2) ◽  
pp. 255-268 ◽  
Author(s):  
D. W. Dunne ◽  
Q. D. Bickle

SUMMARYAntisera were produced by immunizing rabbits with either a trichloroacetic acid-soluble fraction, or a high molecular weight (Mr) fraction ofSchistosoma mansoniSEA (a salinesoluble fraction of homogenized egg). Both of these sera reacted monospecifically in immunoelectrophoresis against unfractionated SEA, recognizing a cathodally migrating antigen. This antigen had been identified previously as being responded to byS. mansoni-infected mouse sera, and has been designated K3(Kappa 3). The rabbit antisera were used to partially characterize antigen K3as havingMrin the range > 750 – 70 K, and being resistant to boiling, resistant to the action of proteases, but sensitive to periodate. It partially binds to Concanavalin A. In addition to SEA, the antigen was present in homogenized cercariae and schistosomula, but not adult worms, and it was also present in detergent extracts of intact cercariae and schistosomula. Using an antibody-dependent cell adherence assay, anti-K3serum was found to react with the surface of live cercariae and with the surface of schistosomula recovered from the skin of mice infected up to 48 h previously. Anti-K3serum also reacted with the surface ofS. bovis, S. haematobiumand to a lesser extentS. japonicumschistosomula.


2002 ◽  
Vol 88 (3) ◽  
pp. 505
Author(s):  
Jurgen Schmitt ◽  
Manfred Wuhrer ◽  
Joseph Hamburger ◽  
Joseph Jourdane ◽  
Reda M. R. Ramzy ◽  
...  

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